iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089606

Ensembl Protein ID

ENSOARP00000010983.1

UniProt Accession

W5PKL0; W5PKL0_SHEEP

Genbank Protein ID

ENSOARP00000010983

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01017347

Gene Name

RNF43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010239.1	ENSOART00000011141.1	ENSOARP00000010983.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.50e-07	32.0	272	312

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiCle+f++g  ++v +C H fh++C+  w        ++ +CPlC
   Q: 272  CAICLEEFSEGqeLRVISCLHEFHRTCVDPW------LHQHRTCPLC 312
           ********55444******************......********** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSGGHQLQLA ALWPWLLMAT LQAGFGRTGL VLAAAVESER SAEQKAIIRV IPLKMDPTGK 60
LNLTLEGVFA GVAEITPAEG KLMQSHPLYL CNASDDDNLE PGFISIVKLE SPQRAPRPCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTGGGTTT AGTGGCTCGA GGACTTGTTG CATATGGAAG ACCAGCACCA GGTGATCTGA 60
CATAATAAAG ATTCGGGATG TGACATTCAA CCTCAAGCAG CACTGAGAAT TCCCAAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0072089--P:stem cell proliferation
GO:0038018--P:Wnt receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001826	Ailuropoda melanoleuca	89.86	0.00e+00	736.00
IUUC-Apl-003222	Anas platyrhynchos	66.24	6.00e-125	441.00
IUUC-Aca-004606	Anolis carolinensis	59.12	9.00e-23	100.00
IUUC-Aly-005399	Arabidopsis lyrata	43.14	1.00e-09	55.10
IUUC-Acl-008182	Aspergillus clavatus	51.16	8.00e-10	56.20
IUUC-Ame-011450	Astyanax mexicanus	47.95	4.00e-51	196.00
IUUC-Bta-012714	Bos taurus	87.36	0.00e+00	1125.00
IUUC-Cel-018318	Caenorhabditis elegans	60.00	2.00e-15	77.00
IUUC-Cja-018949	Callithrix jacchus	90.19	1.00e-104	371.00
IUUC-Cfa-021169	Canis familiaris	73.02	0.00e+00	925.00
IUUC-Cpo-022010	Cavia porcellus	95.58	1.00e-170	593.00
IUUC-Csa-023712	Chlorocebus sabaeus	72.87	0.00e+00	733.00
IUUC-Csv-025869	Ciona savignyi	35.19	8.00e-41	161.00
IUUC-Dno-029646	Dasypus novemcinctus	70.16	0.00e+00	798.00
IUUC-Dor-030965	Dipodomys ordii	76.48	0.00e+00	657.00
IUUC-Ete-033153	Echinops telfairi	70.64	0.00e+00	822.00
IUUC-Eca-034222	Equus caballus	80.59	0.00e+00	974.00
IUUC-Eeu-035320	Erinaceus europaeus	78.26	1.00e-88	320.00
IUUC-Fca-036163	Felis catus	78.21	0.00e+00	993.00
IUUC-Fal-037463	Ficedula albicollis	65.89	3.00e-102	365.00
IUUC-Gmo-039022	Gadus morhua	49.25	1.00e-41	162.00
IUUC-Gga-040209	Gallus gallus	65.62	4.00e-109	389.00
IUUC-Ggo-045644	Gorilla gorilla	82.35	0.00e+00	755.00
IUUC-Hsa-045983	Homo sapiens	82.35	0.00e+00	756.00
IUUC-Itr-049074	Ictidomys tridecemlineatus	77.14	0.00e+00	996.00
IUUC-Loc-052503	Lepisosteus oculatus	50.00	1.00e-50	194.00
IUUC-Laf-054039	Loxodonta africana	77.07	0.00e+00	983.00
IUUC-Mcc-054760	Macaca mulatta	76.88	0.00e+00	952.00
IUUC-Meu-055948	Macropus eugenii	57.16	9.00e-167	580.00
IUUC-Mga-060022	Meleagris gallopavo	62.38	6.00e-81	295.00
IUUC-Mmr-061100	Microcebus murinus	78.42	0.00e+00	1002.00
IUUC-Mdo-062909	Monodelphis domestica	63.35	0.00e+00	772.00
IUUC-Mmu-063835	Mus musculus	70.90	0.00e+00	970.00
IUUC-Mpu-066916	Mustela putorius furo	90.06	0.00e+00	750.00
IUUC-Mlu-067234	Myotis lucifugus	87.89	0.00e+00	714.00
IUUC-Nle-069493	Nomascus leucogenys	78.16	0.00e+00	961.00
IUUC-Oan-073037	Ornithorhynchus anatinus	84.39	1.00e-102	367.00
IUUC-Ocu-074655	Oryctolagus cuniculus	77.14	0.00e+00	964.00
IUUC-Obr-076466	Oryza brachyantha	50.88	3.00e-13	67.80
IUUC-Olo-080549	Oryza longistaminata	50.88	1.00e-12	66.60
IUUC-Ola-087097	Oryzias latipes	39.54	2.00e-44	173.00
IUUC-Oga-088134	Otolemur garnettii	88.41	0.00e+00	792.00
IUUC-Ptr-090726	Pan troglodytes	82.17	0.00e+00	754.00
IUUC-Pan-091958	Papio anubis	77.27	0.00e+00	959.00
IUUC-Psi-093208	Pelodiscus sinensis	65.75	5.00e-119	421.00
IUUC-Pfo-096209	Poecilia formosa	53.06	2.00e-44	173.00
IUUC-Pab-097950	Pongo abelii	90.20	0.00e+00	765.00
IUUC-Pca-100229	Procavia capensis	70.88	0.00e+00	917.00
IUUC-Pva-102480	Pteropus vampyrus	74.33	0.00e+00	929.00
IUUC-Rno-104862	Rattus norvegicus	71.34	0.00e+00	955.00
IUUC-Sha-107577	Sarcophilus harrisii	65.52	0.00e+00	811.00
IUUC-Sar-113693	Sorex araneus	65.95	0.00e+00	776.00
IUUC-Tgu-116568	Taeniopygia guttata	64.77	1.00e-97	350.00
IUUC-Tru-118126	Takifugu rubripes	51.02	4.00e-40	159.00
IUUC-Tni-120241	Tetraodon nigroviridis	38.22	1.00e-31	130.00
IUUC-Tbe-128106	Tupaia belangeri	93.28	5.00e-138	484.00
IUUC-Ttr-128832	Tursiops truncatus	86.75	0.00e+00	763.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence