iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117001

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01019734

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001194.1	ENSTGUT00000001251.1	ENSTGUP00000001239.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.60e-22	77.0	36	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.10e-10	39.7	135	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v + +e +ah++vLaa+S++F a+f+++++esk  +++eikdv+ + +r l++++Yt +++ +
   Q: 36   CDVVIVAESVEMEAHRVVLAACSPYFCAMFTGDMSESK-AKKIEIKDVDGQTLRKLIDYIYTAEIEVT 102
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd + c++L ++a+ ++++hF+
   Q: 135  PTNCLGIRAFADVHACSELLQQANAYAEQHFP 166
           78*****************************6 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

EAAEDEKDQR TVTVNPSHMR KAFKVMNELR SKRLLCDVVI VAESVEMEAH RVVLAACSPY 60
FCAMFTGDMS ESKAKKIEIK DVDGQTLRKL IDYIYTAEIE VTEENVQVLL PAASLLQLMD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCAGCTG AAGATGAAAA GGACCAGCGT ACAGTGACAG TCAATCCCTC TCACATGAGA 60
AAGGCTTTCA AGGTCATGAA TGAATTACGG AGGTACACTT TTGACTTACT GGGTACCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	95.41	0.00e+00	1109.00
IUUC-Apl-003965	Anas platyrhynchos	99.29	0.00e+00	1122.00
IUUC-Aca-004912	Anolis carolinensis	95.56	0.00e+00	1076.00
IUUC-Ame-010670	Astyanax mexicanus	80.53	0.00e+00	932.00
IUUC-Bta-013354	Bos taurus	95.24	0.00e+00	1108.00
IUUC-Bol-016582	Brassica oleracea	30.28	2.00e-13	70.90
IUUC-Bra-017771	Brassica rapa	30.73	1.00e-13	71.60
IUUC-Cel-018136	Caenorhabditis elegans	42.25	4.00e-129	454.00
IUUC-Cja-019183	Callithrix jacchus	91.06	0.00e+00	985.00
IUUC-Cfa-020465	Canis familiaris	95.05	0.00e+00	1103.00
IUUC-Cpo-022115	Cavia porcellus	95.04	0.00e+00	1111.00
IUUC-Csa-024219	Chlorocebus sabaeus	95.58	0.00e+00	1115.00
IUUC-Csv-026032	Ciona savignyi	60.88	0.00e+00	706.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	30.42	2.00e-24	105.00
IUUC-Dre-028524	Danio rerio	75.53	0.00e+00	946.00
IUUC-Dno-029075	Dasypus novemcinctus	96.39	0.00e+00	1100.00
IUUC-Dor-030156	Dipodomys ordii	79.29	0.00e+00	897.00
IUUC-Ete-033064	Echinops telfairi	80.81	0.00e+00	818.00
IUUC-Eca-033887	Equus caballus	95.58	0.00e+00	1110.00
IUUC-Eeu-035244	Erinaceus europaeus	75.22	0.00e+00	861.00
IUUC-Fca-035375	Felis catus	94.71	0.00e+00	1101.00
IUUC-Fal-037119	Ficedula albicollis	99.27	0.00e+00	1085.00
IUUC-Gga-041094	Gallus gallus	99.11	0.00e+00	1118.00
IUUC-Gac-042585	Gasterosteus aculeatus	77.88	0.00e+00	901.00
IUUC-Ggo-045485	Gorilla gorilla	95.07	0.00e+00	1105.00
IUUC-Hsa-046717	Homo sapiens	95.58	0.00e+00	1115.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	95.93	0.00e+00	1116.00
IUUC-Lch-050246	Latimeria chalumnae	88.03	0.00e+00	994.00
IUUC-Laf-053700	Loxodonta africana	95.24	0.00e+00	1108.00
IUUC-Mcc-054732	Macaca mulatta	97.18	0.00e+00	990.00
IUUC-Mga-059994	Meleagris gallopavo	99.42	0.00e+00	1024.00
IUUC-Mdo-062923	Monodelphis domestica	95.40	0.00e+00	1111.00
IUUC-Mmu-063842	Mus musculus	95.22	0.00e+00	1103.00
IUUC-Mpu-066380	Mustela putorius furo	95.22	0.00e+00	1106.00
IUUC-Mlu-067922	Myotis lucifugus	95.41	0.00e+00	1110.00
IUUC-Nle-069761	Nomascus leucogenys	95.40	0.00e+00	1112.00
IUUC-Opr-070287	Ochotona princeps	87.39	0.00e+00	989.00
IUUC-Ont-071654	Oreochromis niloticus	80.00	0.00e+00	949.00
IUUC-Ocu-074957	Oryctolagus cuniculus	94.89	0.00e+00	1098.00
IUUC-Ola-086853	Oryzias latipes	79.12	0.00e+00	900.00
IUUC-Oga-088559	Otolemur garnettii	94.71	0.00e+00	1102.00
IUUC-Oar-089925	Ovis aries	95.41	0.00e+00	1108.00
IUUC-Ptr-091487	Pan troglodytes	95.58	0.00e+00	1115.00
IUUC-Pan-091705	Papio anubis	95.58	0.00e+00	1115.00
IUUC-Psi-093478	Pelodiscus sinensis	93.13	0.00e+00	1051.00
IUUC-Pfo-097450	Poecilia formosa	80.00	0.00e+00	886.00
IUUC-Pab-097618	Pongo abelii	95.40	0.00e+00	1112.00
IUUC-Sha-106935	Sarcophilus harrisii	97.55	0.00e+00	730.00
IUUC-Ssc-115599	Sus scrofa	95.58	0.00e+00	1112.00
IUUC-Tru-118078	Takifugu rubripes	78.76	0.00e+00	936.00
IUUC-Tsy-119161	Tarsius syrichta	83.33	0.00e+00	860.00
IUUC-Tni-120888	Tetraodon nigroviridis	76.68	0.00e+00	879.00
IUUC-Tre-122227	Trichoderma reesei	30.93	9.00e-07	46.20
IUUC-Tbe-127285	Tupaia belangeri	80.61	0.00e+00	644.00
IUUC-Ttr-128884	Tursiops truncatus	79.14	7.00e-143	500.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence