iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069806

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01074175

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016281.2	ENSNLET00000020747.2	ENSNLEP00000019753.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.40e-07	30.3	21	61
E3 activity/RING/U-box	2.30e-09	37.2	16	85

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + + + +CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRGCVsRCW-----EVQVSPTCPVCK 61
           ********99.999************9999.....799999*****6 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC++ ++++rd v+l +G+ + r ++ ++ + + + tcPv++ + ++ dl  n+tl +l+++ + e
   Q: 16   KEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSpTCPVCKDRASPADLRTNHTLNNLVEKLLRE 85
           689******************************97766669**********************9987765 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MERSPDVSPG PSRSFKEELL CAVCYDPFRD AVTLRCGHNF CRGCVSRCWE VQVSPTCPVC 60
KDRASPADLR TNHTLNNLVE KLLREEAEGA RWTSYRFSRV CRLHRGQLSL FCLEDKELLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGGA GCCCCGACGT GTCCCCCGGG CCTTCCCGCT CCTTCAAGGA GGAGTTGCTC 60
TGCGCAGTCT GCTACGACCC CTTCCGCGAC GCAGTGACTC TGCGCTGCGG CCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	90.15	0.00e+00	878.00
IUUC-Apl-003958	Anas platyrhynchos	54.59	5.00e-126	444.00
IUUC-Aca-005199	Anolis carolinensis	47.68	4.00e-118	418.00
IUUC-Ame-011964	Astyanax mexicanus	35.89	1.00e-72	267.00
IUUC-Bta-013359	Bos taurus	88.13	0.00e+00	841.00
IUUC-Cja-018900	Callithrix jacchus	80.80	0.00e+00	773.00
IUUC-Cfa-020685	Canis familiaris	90.15	0.00e+00	878.00
IUUC-Cpo-022253	Cavia porcellus	80.73	0.00e+00	755.00
IUUC-Csa-023777	Chlorocebus sabaeus	98.07	0.00e+00	948.00
IUUC-Dre-028185	Danio rerio	36.62	1.00e-59	223.00
IUUC-Dno-029065	Dasypus novemcinctus	84.23	0.00e+00	836.00
IUUC-Dor-030248	Dipodomys ordii	65.40	9.00e-103	365.00
IUUC-Ete-033183	Echinops telfairi	73.13	0.00e+00	678.00
IUUC-Eca-033263	Equus caballus	88.76	0.00e+00	754.00
IUUC-Eeu-034699	Erinaceus europaeus	79.34	1.00e-100	360.00
IUUC-Fca-036366	Felis catus	88.49	0.00e+00	867.00
IUUC-Fal-037257	Ficedula albicollis	57.21	3.00e-147	514.00
IUUC-Gmo-038512	Gadus morhua	35.62	3.00e-69	255.00
IUUC-Gga-041125	Gallus gallus	55.34	4.00e-97	347.00
IUUC-Gac-042136	Gasterosteus aculeatus	34.89	1.00e-69	256.00
IUUC-Ggo-045233	Gorilla gorilla	97.24	1.00e-167	581.00
IUUC-Hsa-046042	Homo sapiens	98.29	0.00e+00	949.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	90.55	0.00e+00	859.00
IUUC-Loc-051729	Lepisosteus oculatus	36.14	1.00e-80	293.00
IUUC-Laf-054322	Loxodonta africana	89.67	0.00e+00	855.00
IUUC-Mcc-055555	Macaca mulatta	95.77	0.00e+00	928.00
IUUC-Meu-055900	Macropus eugenii	79.25	0.00e+00	753.00
IUUC-Mga-059380	Meleagris gallopavo	55.93	4.00e-105	374.00
IUUC-Mmr-061296	Microcebus murinus	90.58	0.00e+00	871.00
IUUC-Mdo-062811	Monodelphis domestica	79.47	0.00e+00	754.00
IUUC-Mmu-063718	Mus musculus	78.52	0.00e+00	751.00
IUUC-Mpu-066219	Mustela putorius furo	89.67	0.00e+00	850.00
IUUC-Mlu-067033	Myotis lucifugus	84.37	0.00e+00	825.00
IUUC-Opr-070248	Ochotona princeps	80.96	0.00e+00	735.00
IUUC-Ont-072083	Oreochromis niloticus	32.97	1.00e-67	250.00
IUUC-Oan-073364	Ornithorhynchus anatinus	68.70	3.00e-94	337.00
IUUC-Ocu-074572	Oryctolagus cuniculus	92.93	0.00e+00	905.00
IUUC-Oga-088378	Otolemur garnettii	88.49	0.00e+00	847.00
IUUC-Oar-089516	Ovis aries	87.44	0.00e+00	829.00
IUUC-Ptr-091313	Pan troglodytes	98.29	0.00e+00	949.00
IUUC-Pan-092877	Papio anubis	98.29	0.00e+00	949.00
IUUC-Psi-093928	Pelodiscus sinensis	58.61	3.00e-153	535.00
IUUC-Pfo-096690	Poecilia formosa	35.12	1.00e-66	247.00
IUUC-Pab-098624	Pongo abelii	97.86	0.00e+00	942.00
IUUC-Pca-100469	Procavia capensis	83.48	0.00e+00	790.00
IUUC-Pva-103227	Pteropus vampyrus	89.29	0.00e+00	869.00
IUUC-Rno-105778	Rattus norvegicus	78.31	0.00e+00	751.00
IUUC-Sha-107392	Sarcophilus harrisii	68.29	0.00e+00	637.00
IUUC-Sar-113297	Sorex araneus	72.09	3.00e-53	201.00
IUUC-Ssc-115739	Sus scrofa	88.35	0.00e+00	838.00
IUUC-Tru-117718	Takifugu rubripes	31.55	4.00e-61	228.00
IUUC-Tni-120490	Tetraodon nigroviridis	34.59	7.00e-65	241.00
IUUC-Tbe-127926	Tupaia belangeri	85.10	3.00e-121	428.00
IUUC-Ttr-129293	Tursiops truncatus	89.51	0.00e+00	863.00
IUUC-Vpa-130379	Vicugna pacos	90.60	6.00e-159	553.00
IUUC-Xma-134222	Xiphophorus maculatus	33.55	1.00e-60	226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence