iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074572

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02011046

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007658.2	ENSOCUT00000007656.2	ENSOCUP00000006623.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.10e-09	37.3	24	93
E3 activity/RING/RING	4.40e-06	27.2	29	69

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawcee 71
            ee+lC++ ++++rd v+l +G+ + r ++ ++ + + + tcPv++ + ++ dl  n+tl +l+++ + e
   Q: 24   KEELLCAVCYDPFRDAVTLHCGHNFCRGCVSRCWEVQVTpTCPVCKDRASPADLRTNHTLNNLVEKLLRE 93
           689*******************************888888***********************9987765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l CgH f++ C+  +w     + + + +CP+C+
   Q: 29   CAVCYDPFRD-AVTLHCGHNFCRGCVsRCW-----EVQVTPTCPVCK 69
           ********99.999************9999.....799999*****6 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

ALKAAARAME PGPAVSPGPS RSFKEELLCA VCYDPFRDAV TLHCGHNFCR GCVSRCWEVQ 60
VTPTCPVCKD RASPADLRTN HTLNNLVEKL LREEAEGARW TGHRSPRLCR LHRGQFSLFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTGAAGG CGGCGGCTCG TGCCATGGAG CCTGGCCCTG CCGTGTCCCC TGGGCCTTCC 60
CGCTCCTTCA AGGAGGAGCT GCTCTGCGCC GTCTGCTACG ACCCCTTCCG CGACGCCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	91.87	0.00e+00	951.00
IUUC-Apl-003958	Anas platyrhynchos	54.38	6.00e-134	470.00
IUUC-Aca-005199	Anolis carolinensis	46.53	5.00e-125	441.00
IUUC-Ame-011964	Astyanax mexicanus	36.53	1.00e-74	273.00
IUUC-Bta-013359	Bos taurus	89.17	0.00e+00	905.00
IUUC-Cja-018900	Callithrix jacchus	80.16	0.00e+00	814.00
IUUC-Cfa-020685	Canis familiaris	91.67	0.00e+00	948.00
IUUC-Cpo-022253	Cavia porcellus	81.30	0.00e+00	806.00
IUUC-Csa-023777	Chlorocebus sabaeus	93.90	0.00e+00	965.00
IUUC-Dre-028185	Danio rerio	36.36	1.00e-58	220.00
IUUC-Dno-029065	Dasypus novemcinctus	85.74	0.00e+00	899.00
IUUC-Dor-030248	Dipodomys ordii	65.78	2.00e-102	365.00
IUUC-Ete-033183	Echinops telfairi	75.00	0.00e+00	740.00
IUUC-Eca-033263	Equus caballus	89.60	0.00e+00	817.00
IUUC-Eeu-034699	Erinaceus europaeus	80.25	7.00e-116	410.00
IUUC-Fca-036366	Felis catus	90.65	0.00e+00	939.00
IUUC-Fal-037257	Ficedula albicollis	58.04	5.00e-159	553.00
IUUC-Gmo-038512	Gadus morhua	35.15	5.00e-69	254.00
IUUC-Gga-041125	Gallus gallus	55.69	6.00e-108	383.00
IUUC-Gac-042136	Gasterosteus aculeatus	35.71	5.00e-70	258.00
IUUC-Ggo-045233	Gorilla gorilla	94.92	3.00e-180	623.00
IUUC-Hsa-046042	Homo sapiens	93.90	0.00e+00	966.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	91.46	0.00e+00	922.00
IUUC-Lch-049548	Latimeria chalumnae	35.51	6.00e-82	297.00
IUUC-Loc-051729	Lepisosteus oculatus	35.12	1.00e-81	296.00
IUUC-Laf-054322	Loxodonta africana	90.38	0.00e+00	915.00
IUUC-Mcc-055555	Macaca mulatta	91.77	0.00e+00	946.00
IUUC-Meu-055900	Macropus eugenii	79.20	0.00e+00	796.00
IUUC-Mga-059380	Meleagris gallopavo	57.36	4.00e-107	380.00
IUUC-Mmr-061296	Microcebus murinus	90.24	0.00e+00	922.00
IUUC-Mdo-062811	Monodelphis domestica	79.02	0.00e+00	805.00
IUUC-Mmu-063718	Mus musculus	79.84	0.00e+00	813.00
IUUC-Mpu-066219	Mustela putorius furo	91.04	0.00e+00	916.00
IUUC-Mlu-067033	Myotis lucifugus	84.55	0.00e+00	884.00
IUUC-Nle-069806	Nomascus leucogenys	93.71	0.00e+00	902.00
IUUC-Opr-070248	Ochotona princeps	83.20	0.00e+00	806.00
IUUC-Ont-072083	Oreochromis niloticus	32.79	2.00e-70	259.00
IUUC-Oan-073364	Ornithorhynchus anatinus	70.85	1.00e-100	359.00
IUUC-Ola-086686	Oryzias latipes	32.29	7.00e-60	224.00
IUUC-Oga-088378	Otolemur garnettii	89.63	0.00e+00	904.00
IUUC-Oar-089516	Ovis aries	88.31	0.00e+00	891.00
IUUC-Ptr-091313	Pan troglodytes	93.90	0.00e+00	966.00
IUUC-Pan-092877	Papio anubis	94.11	0.00e+00	966.00
IUUC-Psi-093928	Pelodiscus sinensis	59.38	4.00e-165	574.00
IUUC-Pfo-096831	Poecilia formosa	32.93	1.00e-65	243.00
IUUC-Pab-098624	Pongo abelii	93.70	0.00e+00	959.00
IUUC-Pca-100469	Procavia capensis	83.09	0.00e+00	842.00
IUUC-Pva-103227	Pteropus vampyrus	90.45	0.00e+00	939.00
IUUC-Rno-105778	Rattus norvegicus	79.63	0.00e+00	814.00
IUUC-Sha-107392	Sarcophilus harrisii	69.01	0.00e+00	681.00
IUUC-Sar-113297	Sorex araneus	70.54	4.00e-52	197.00
IUUC-Ssc-115739	Sus scrofa	89.79	0.00e+00	907.00
IUUC-Tru-117718	Takifugu rubripes	32.00	1.00e-62	233.00
IUUC-Tni-120490	Tetraodon nigroviridis	34.43	2.00e-69	256.00
IUUC-Tbe-127926	Tupaia belangeri	86.07	1.00e-138	486.00
IUUC-Ttr-129293	Tursiops truncatus	90.65	0.00e+00	932.00
IUUC-Vpa-130379	Vicugna pacos	89.93	1.00e-157	548.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence