iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014955.1	ENSAMET00000016449.1	ENSAMEP00000015794.1
ENSAMEG00000014955.1	ENSAMET00000016457.1	ENSAMEP00000015802.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-11	43.6	430	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++lydy+++ +de ++   d+++ i  e  degW++g    +g  GlfP+n+v+ l
   Q: 430  IALYDYQGEGSDEISFDPDDIITDI--EMVDEGWWRG--RCHGHFGLFPANYVKLL 481
           79**********************9..9*********..8*************977 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MWKSVVGHDV SVTVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRTE HINIHQLRNK 60
VSEEHDSLKK KEMESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVEKH SSQTDAAKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGT CTGTAGTAGG GCATGATGTA TCTGTTACCG TGGAGACCCA GGGTGATGAC 60
TGGGACACAG ACCCTGACTT TGTGGTGAGT TTGGGAGTAG CTTTGCTTGG AAAATCAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012591	Bos taurus	86.53	0.00e+00	691.00
IUUC-Cja-019982	Callithrix jacchus	84.16	0.00e+00	686.00
IUUC-Cfa-020262	Canis familiaris	88.46	0.00e+00	706.00
IUUC-Cpo-021362	Cavia porcellus	81.33	0.00e+00	640.00
IUUC-Csa-023911	Chlorocebus sabaeus	85.09	0.00e+00	691.00
IUUC-Dor-030437	Dipodomys ordii	75.31	6.00e-172	597.00
IUUC-Ete-033160	Echinops telfairi	72.71	5.00e-153	533.00
IUUC-Eca-033269	Equus caballus	85.89	0.00e+00	740.00
IUUC-Eeu-035032	Erinaceus europaeus	71.69	4.00e-127	447.00
IUUC-Fca-035999	Felis catus	87.90	0.00e+00	800.00
IUUC-Gga-040335	Gallus gallus	67.14	7.00e-105	374.00
IUUC-Ggo-044505	Gorilla gorilla	83.95	0.00e+00	686.00
IUUC-Hsa-046728	Homo sapiens	89.55	6.00e-169	587.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	67.21	4.00e-165	574.00
IUUC-Laf-054202	Loxodonta africana	80.93	0.00e+00	663.00
IUUC-Mcc-055824	Macaca mulatta	84.89	0.00e+00	694.00
IUUC-Mmr-061281	Microcebus murinus	73.25	2.00e-167	581.00
IUUC-Mdo-062515	Monodelphis domestica	67.48	2.00e-149	522.00
IUUC-Mmu-064341	Mus musculus	80.61	0.00e+00	674.00
IUUC-Mpu-066565	Mustela putorius furo	91.29	0.00e+00	754.00
IUUC-Mlu-066942	Myotis lucifugus	81.58	0.00e+00	684.00
IUUC-Nle-069436	Nomascus leucogenys	85.27	0.00e+00	691.00
IUUC-Opr-070288	Ochotona princeps	76.45	7.00e-169	586.00
IUUC-Ocu-074686	Oryctolagus cuniculus	79.88	3.00e-178	618.00
IUUC-Ola-086894	Oryzias latipes	59.79	7.00e-94	337.00
IUUC-Oga-088585	Otolemur garnettii	77.28	0.00e+00	664.00
IUUC-Oar-089686	Ovis aries	87.04	0.00e+00	742.00
IUUC-Ptr-090461	Pan troglodytes	90.40	1.00e-170	592.00
IUUC-Pan-091887	Papio anubis	84.65	0.00e+00	693.00
IUUC-Psi-093785	Pelodiscus sinensis	51.65	3.00e-139	488.00
IUUC-Pab-098222	Pongo abelii	85.30	0.00e+00	692.00
IUUC-Pca-100668	Procavia capensis	82.85	0.00e+00	682.00
IUUC-Pva-102767	Pteropus vampyrus	73.66	3.00e-170	591.00
IUUC-Rno-106001	Rattus norvegicus	82.89	0.00e+00	679.00
IUUC-Sar-113338	Sorex araneus	76.41	6.00e-175	606.00
IUUC-Ssc-116027	Sus scrofa	84.34	0.00e+00	733.00
IUUC-Tgu-117472	Taeniopygia guttata	56.51	3.00e-147	514.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence