iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011849.2	ENSSSCT00000012961.2	ENSSSCP00000012620.2
ENSSSCG00000011849.2	ENSSSCT00000024458.1	ENSSSCP00000023403.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	94.24	0.00e+00	1667.00	IUUC-Hsa-046670

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKAAC KRRSWMSKVF SGKRLEAEFP PHHSQSTFRK TSPTPGGPAG EGSLQSLTCL 120

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Nucleotide Sequence
(Fasta)

AGGCTGGGGA GCAGCAGCAT GCAGCCGGAG GAGGGCACAG GCTGGCTGCT GGAGCTGCTG 60
TCCGAGGTGC AGCTGCAACA GTATTTCCTG CGGCTCCGTG ACGACCTCAA CGTTACCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0042127--P:regulation of cell proliferation
GO:2000369--P:regulation of clathrin-dependent endocytosis
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	92.05	0.00e+00	1674.00
IUUC-Aca-004315	Anolis carolinensis	88.97	9.00e-74	268.00
IUUC-Ame-011350	Astyanax mexicanus	54.33	0.00e+00	1032.00
IUUC-Bta-012325	Bos taurus	95.96	0.00e+00	1773.00
IUUC-Cel-018130	Caenorhabditis elegans	36.51	6.00e-90	325.00
IUUC-Cja-019545	Callithrix jacchus	87.77	0.00e+00	1559.00
IUUC-Cfa-020706	Canis familiaris	95.01	0.00e+00	1759.00
IUUC-Cpo-022032	Cavia porcellus	87.38	0.00e+00	1646.00
IUUC-Csa-023936	Chlorocebus sabaeus	93.56	0.00e+00	1703.00
IUUC-Csv-026328	Ciona savignyi	58.52	7.00e-172	596.00
IUUC-Dre-028714	Danio rerio	63.11	0.00e+00	1220.00
IUUC-Dno-029525	Dasypus novemcinctus	94.15	0.00e+00	1734.00
IUUC-Dme-031778	Drosophila melanogaster	55.33	4.00e-143	502.00
IUUC-Ete-032225	Echinops telfairi	90.43	0.00e+00	858.00
IUUC-Fca-035664	Felis catus	95.59	0.00e+00	1815.00
IUUC-Gmo-039543	Gadus morhua	59.19	0.00e+00	944.00
IUUC-Gga-040241	Gallus gallus	69.37	0.00e+00	1318.00
IUUC-Gac-041457	Gasterosteus aculeatus	61.22	0.00e+00	1125.00
IUUC-Ggo-045333	Gorilla gorilla	91.00	0.00e+00	1678.00
IUUC-Hsa-046670	Homo sapiens	94.24	0.00e+00	1674.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	92.42	0.00e+00	1734.00
IUUC-Lch-049670	Latimeria chalumnae	62.43	0.00e+00	1212.00
IUUC-Loc-052870	Lepisosteus oculatus	62.65	0.00e+00	1272.00
IUUC-Laf-053782	Loxodonta africana	90.90	0.00e+00	1678.00
IUUC-Mcc-055874	Macaca mulatta	93.65	0.00e+00	1695.00
IUUC-Mga-059717	Meleagris gallopavo	70.84	0.00e+00	1365.00
IUUC-Mdo-062270	Monodelphis domestica	84.60	0.00e+00	1605.00
IUUC-Mmu-063861	Mus musculus	92.14	0.00e+00	1763.00
IUUC-Mpu-066127	Mustela putorius furo	94.42	0.00e+00	1357.00
IUUC-Mlu-067937	Myotis lucifugus	84.76	0.00e+00	1649.00
IUUC-Nle-069298	Nomascus leucogenys	93.48	0.00e+00	1389.00
IUUC-Ont-072437	Oreochromis niloticus	59.73	0.00e+00	1214.00
IUUC-Oan-073708	Ornithorhynchus anatinus	70.37	3.00e-113	402.00
IUUC-Ola-087023	Oryzias latipes	62.01	0.00e+00	1147.00
IUUC-Pan-091857	Papio anubis	94.25	1.00e-93	335.00
IUUC-Psi-093401	Pelodiscus sinensis	54.84	1.00e-147	516.00
IUUC-Pfo-097455	Poecilia formosa	59.19	0.00e+00	1194.00
IUUC-Rno-105586	Rattus norvegicus	91.86	0.00e+00	1734.00
IUUC-Sha-106868	Sarcophilus harrisii	84.11	0.00e+00	1602.00
IUUC-Tgu-116592	Taeniopygia guttata	69.54	0.00e+00	1317.00
IUUC-Tru-117852	Takifugu rubripes	70.04	3.00e-180	625.00
IUUC-Tsy-119087	Tarsius syrichta	98.14	1.00e-158	553.00
IUUC-Tni-120826	Tetraodon nigroviridis	62.60	0.00e+00	1222.00
IUUC-Xtr-132069	Xenopus tropicalis	64.33	0.00e+00	1169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence