iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.80e-10	39.8	73	135

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D ++  + + f +hk+v+a++S++Fy+ ++++ + +    +v+++d+ p  + +++ + Ytgkl++
   Q: 73   CDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTK----RVDLNDIAPLGLATVIAYAYTGKLTL 135
           566666679*********************9988765....6**********************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAPKKKTLKK NKPEINEMTI IVEDSPLNKL NALNGLLGGE NSLSCVSSEL TDTSYGPNLL 60
EGLSKMRQES FLCDLVIGTK TKSFDVHKSV MASCSEYFYN ILKNDPSTKR VDLNDIAPLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAAAGAG AAGCTGGGAC CGCAACTACC AACTGCCGCC TGGATCCTAG GGTGTGTATG 60
GCTGTGTGGG TGGGAGATAG TGGGGGTGTC TGAACGTTGG TGCCAGTAGA GCTATTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030604--KLHL31
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016021--C:integral component of membrane
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007519--P:skeletal muscle tissue development

KEGG

rno:315833

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001763	Ailuropoda melanoleuca	91.07	0.00e+00	1150.00
IUUC-Apl-003259	Anas platyrhynchos	81.52	0.00e+00	1041.00
IUUC-Aca-004983	Anolis carolinensis	80.71	0.00e+00	1005.00
IUUC-Bta-013005	Bos taurus	89.97	0.00e+00	1137.00
IUUC-Cja-019238	Callithrix jacchus	90.91	0.00e+00	1146.00
IUUC-Cfa-020072	Canis familiaris	89.77	0.00e+00	1123.00
IUUC-Cpo-021329	Cavia porcellus	88.22	0.00e+00	1057.00
IUUC-Csa-023691	Chlorocebus sabaeus	91.91	0.00e+00	1157.00
IUUC-Cho-024922	Choloepus hoffmanni	92.31	0.00e+00	706.00
IUUC-Dre-028661	Danio rerio	73.75	0.00e+00	934.00
IUUC-Dno-029076	Dasypus novemcinctus	90.45	0.00e+00	1152.00
IUUC-Dor-031088	Dipodomys ordii	77.02	0.00e+00	914.00
IUUC-Ete-032920	Echinops telfairi	89.67	5.00e-163	567.00
IUUC-Eca-034024	Equus caballus	92.05	0.00e+00	1159.00
IUUC-Eeu-035306	Erinaceus europaeus	85.46	3.00e-119	422.00
IUUC-Fca-036158	Felis catus	91.40	0.00e+00	1148.00
IUUC-Fal-037022	Ficedula albicollis	80.23	0.00e+00	1036.00
IUUC-Fso-038326	Fusarium solani	33.85	6.00e-04	38.10
IUUC-Gga-040196	Gallus gallus	81.46	0.00e+00	1036.00
IUUC-Gac-041632	Gasterosteus aculeatus	70.76	0.00e+00	930.00
IUUC-Ggo-045013	Gorilla gorilla	90.56	0.00e+00	1134.00
IUUC-Hsa-046095	Homo sapiens	91.42	0.00e+00	1152.00
IUUC-Itr-048718	Ictidomys tridecemlineatus	92.37	0.00e+00	1155.00
IUUC-Lch-049472	Latimeria chalumnae	75.00	0.00e+00	942.00
IUUC-Loc-052506	Lepisosteus oculatus	74.03	0.00e+00	962.00
IUUC-Laf-053923	Loxodonta africana	91.72	0.00e+00	1150.00
IUUC-Mcc-054899	Macaca mulatta	91.75	0.00e+00	1156.00
IUUC-Meu-056196	Macropus eugenii	87.12	0.00e+00	895.00
IUUC-Mga-059467	Meleagris gallopavo	81.46	0.00e+00	1038.00
IUUC-Mmr-061561	Microcebus murinus	91.91	0.00e+00	1157.00
IUUC-Mdo-063046	Monodelphis domestica	84.79	0.00e+00	1109.00
IUUC-Mmu-064137	Mus musculus	97.08	0.00e+00	1209.00
IUUC-Mpu-066493	Mustela putorius furo	90.58	0.00e+00	1146.00
IUUC-Mlu-067496	Myotis lucifugus	89.97	0.00e+00	1167.00
IUUC-Nle-069165	Nomascus leucogenys	91.10	0.00e+00	1152.00
IUUC-Opr-071189	Ochotona princeps	90.58	0.00e+00	1152.00
IUUC-Ont-072402	Oreochromis niloticus	71.76	0.00e+00	945.00
IUUC-Oan-073016	Ornithorhynchus anatinus	83.41	0.00e+00	1058.00
IUUC-Ocu-074754	Oryctolagus cuniculus	91.07	0.00e+00	1145.00
IUUC-Oga-088554	Otolemur garnettii	91.88	0.00e+00	1155.00
IUUC-Oar-089224	Ovis aries	89.79	0.00e+00	1109.00
IUUC-Ptr-091386	Pan troglodytes	91.42	0.00e+00	1152.00
IUUC-Pan-091805	Papio anubis	91.91	0.00e+00	1156.00
IUUC-Psi-093677	Pelodiscus sinensis	81.36	0.00e+00	1058.00
IUUC-Pma-094418	Petromyzon marinus	64.90	0.00e+00	836.00
IUUC-Pab-098736	Pongo abelii	91.42	0.00e+00	1150.00
IUUC-Pca-100924	Procavia capensis	89.00	0.00e+00	1133.00
IUUC-Pva-102855	Pteropus vampyrus	90.78	0.00e+00	1177.00
IUUC-Sha-106994	Sarcophilus harrisii	84.14	0.00e+00	1103.00
IUUC-Ssc-115520	Sus scrofa	91.59	0.00e+00	1158.00
IUUC-Tgu-116543	Taeniopygia guttata	80.06	0.00e+00	1026.00
IUUC-Tni-120722	Tetraodon nigroviridis	72.39	0.00e+00	889.00
IUUC-Tvi-122419	Trichoderma virens	31.40	7.00e-06	44.30
IUUC-Tbe-127534	Tupaia belangeri	91.56	0.00e+00	1149.00
IUUC-Ttr-128994	Tursiops truncatus	91.75	0.00e+00	1159.00
IUUC-Vpa-130695	Vicugna pacos	93.08	0.00e+00	723.00
IUUC-Xtr-132249	Xenopus tropicalis	77.41	0.00e+00	972.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence