iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074331

Ensembl Protein ID

ENSOCUP00000004355.3

UniProt Accession

G1SN22; G1SN22_RABIT

Genbank Protein ID

ENSOCUP00000004355

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02018115

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000005026.3	ENSOCUT00000005027.3	ENSOCUP00000004355.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-67	223.6	269	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deLt+k+G+++++i+ke+ + gW+kg  el+gk+G+fP+nF ++++
   Q: 269  AKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGETGWWKG--ELNGKEGVFPDNFAVQIS 328
           689***************************************..9*************9986 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE 60
AESKDDNLPI KRERHGNVAS LVQRISTYGL PAGGIQPHPQ TKNIKKKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCAGGGG CCTGCTTCGA TCAGAAAAGT AACACAGCGT CACTGCTGCG AAAAGTGGGG 60
CACCCCAAGC TCACTCTGCC TATCGGCAAA AACCTTTTCC CGTACATCCG AGGCGGCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	89.72	0.00e+00	948.00
IUUC-Apl-003573	Anas platyrhynchos	62.65	2.00e-157	548.00
IUUC-Aca-005118	Anolis carolinensis	62.81	2.00e-162	565.00
IUUC-Ame-010657	Astyanax mexicanus	53.28	2.00e-92	333.00
IUUC-Bta-012577	Bos taurus	86.31	0.00e+00	843.00
IUUC-Cja-020010	Callithrix jacchus	89.56	0.00e+00	920.00
IUUC-Cfa-020040	Canis familiaris	90.17	0.00e+00	941.00
IUUC-Cpo-021906	Cavia porcellus	82.52	0.00e+00	803.00
IUUC-Csa-024008	Chlorocebus sabaeus	91.12	0.00e+00	895.00
IUUC-Cho-024359	Choloepus hoffmanni	95.20	1.00e-57	217.00
IUUC-Csv-026228	Ciona savignyi	40.37	1.00e-25	108.00
IUUC-Dre-027661	Danio rerio	56.07	2.00e-95	343.00
IUUC-Dno-029568	Dasypus novemcinctus	85.09	0.00e+00	839.00
IUUC-Dor-030286	Dipodomys ordii	76.21	0.00e+00	718.00
IUUC-Ete-032576	Echinops telfairi	85.37	2.00e-111	395.00
IUUC-Eca-033438	Equus caballus	89.41	0.00e+00	941.00
IUUC-Eeu-034588	Erinaceus europaeus	73.37	1.00e-149	522.00
IUUC-Fca-036597	Felis catus	90.97	0.00e+00	968.00
IUUC-Fal-037305	Ficedula albicollis	63.54	4.00e-163	568.00
IUUC-Gmo-039516	Gadus morhua	45.59	4.00e-67	249.00
IUUC-Gga-040979	Gallus gallus	65.34	3.00e-178	618.00
IUUC-Gac-041945	Gasterosteus aculeatus	52.00	6.00e-81	295.00
IUUC-Ggo-044488	Gorilla gorilla	91.74	0.00e+00	927.00
IUUC-Hsa-045909	Homo sapiens	91.28	0.00e+00	924.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	92.93	9.00e-126	442.00
IUUC-Lch-049481	Latimeria chalumnae	56.20	3.00e-155	541.00
IUUC-Loc-052715	Lepisosteus oculatus	52.40	1.00e-140	493.00
IUUC-Laf-053444	Loxodonta africana	86.65	0.00e+00	901.00
IUUC-Mcc-054844	Macaca mulatta	91.28	0.00e+00	896.00
IUUC-Meu-056491	Macropus eugenii	65.33	2.00e-178	619.00
IUUC-Mga-060154	Meleagris gallopavo	65.18	4.00e-173	601.00
IUUC-Mmr-061099	Microcebus murinus	89.10	0.00e+00	912.00
IUUC-Mdo-062769	Monodelphis domestica	71.47	0.00e+00	759.00
IUUC-Mmu-063136	Mus musculus	86.56	0.00e+00	804.00
IUUC-Mpu-066509	Mustela putorius furo	89.23	0.00e+00	865.00
IUUC-Mlu-067174	Myotis lucifugus	86.29	0.00e+00	885.00
IUUC-Nle-070147	Nomascus leucogenys	91.43	0.00e+00	931.00
IUUC-Opr-070752	Ochotona princeps	85.19	3.00e-171	595.00
IUUC-Ont-071810	Oreochromis niloticus	56.69	3.00e-102	365.00
IUUC-Oan-072731	Ornithorhynchus anatinus	73.44	2.00e-168	585.00
IUUC-Ola-086404	Oryzias latipes	46.54	1.00e-91	330.00
IUUC-Oga-088200	Otolemur garnettii	90.34	0.00e+00	977.00
IUUC-Oar-090423	Ovis aries	84.45	0.00e+00	807.00
IUUC-Ptr-091230	Pan troglodytes	91.90	0.00e+00	931.00
IUUC-Pan-091823	Papio anubis	91.12	0.00e+00	894.00
IUUC-Psi-093127	Pelodiscus sinensis	64.07	3.00e-165	575.00
IUUC-Pfo-096539	Poecilia formosa	50.29	6.00e-89	322.00
IUUC-Pab-097666	Pongo abelii	91.90	0.00e+00	921.00
IUUC-Pca-100812	Procavia capensis	80.38	7.00e-130	457.00
IUUC-Pva-102260	Pteropus vampyrus	82.96	0.00e+00	743.00
IUUC-Rno-106038	Rattus norvegicus	84.84	0.00e+00	821.00
IUUC-Sha-106975	Sarcophilus harrisii	72.47	0.00e+00	724.00
IUUC-Sar-113386	Sorex araneus	86.59	1.00e-106	380.00
IUUC-Ssc-115569	Sus scrofa	93.52	3.00e-117	414.00
IUUC-Tgu-117104	Taeniopygia guttata	64.68	5.00e-177	614.00
IUUC-Tru-117649	Takifugu rubripes	54.47	5.00e-99	355.00
IUUC-Tsy-119258	Tarsius syrichta	82.06	0.00e+00	820.00
IUUC-Tni-120755	Tetraodon nigroviridis	46.19	9.00e-129	454.00
IUUC-Tbe-127842	Tupaia belangeri	71.41	0.00e+00	659.00
IUUC-Ttr-129205	Tursiops truncatus	88.07	0.00e+00	779.00
IUUC-Vpa-130434	Vicugna pacos	85.18	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence