iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054297

UUCD1 version

UUC-LoA-00351

Ensembl Protein ID

ENSLAFP00000008622.3

UniProt Accession

G3T5B8; G3T5B8_LOXAF

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010286.3	ENSLAFT00000010294.3	ENSLAFP00000008622.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.10e-87	294.1	974	1216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 69   ynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslve 155
             ++W+ freql++ +++f      y+             +++w+++i+ed ++rll+l+ +l++ +R+++++++r+l++ +++   
   Q: 974  KPTFWPLFREQLCRRTSLF------YTIW-----------AQAWSRDIAED-RRRLLQLCPRLNKVLRHEQNFADRFLPDEEAA--- 1039
           5689***************......7666...........9**********.********************************... PP
   S: 156  LslnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhleslla 241
                +a++k+++Ea++++ +q++++++++ +++  + +d+Yl+++e++  + +++a+++++++++++Ll +ve+   +       +
   Q: 1040 -----QALGKTCWEALVSPLVQNITSPDAEGVSSLgWLLDQYLEQRENSRSPLSRAASFASRVRRLCHLLIHVEPPPGP-------S 1114
           .....9*************************************************************************.......* PP
   S: 242  elvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFl 326
           + ++    +k+++  + +   s vl+  +l+++++++ s+++eq++++l+a++++ d   +V+r++el+++lq++ se+F+++a+F+
   Q: 1115 PEPSPRPFSKNSKGWDRSPGPSAVLPssSLKNITQCWLSVVQEQVSRFLAAAWRASD---FVPRYCELYERLQRA-SELFGPRAAFT 1197
           *************************999*****************************...*************97.68********* PP
   S: 327  kaldkafetfvnknsvlka 345
            al+++f+ +++++s+ ++
   Q: 1198 LALRSGFSGALLQQSFPHR 1216
           **************98665 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MVGERCTRDL MVPLGPRLQA FPEELLRQRP GHDGCPEYLI RWSVLKCGEV GRVGVGSEEK 60
AEHILMWLSA PEVYANCPML LGERVLSKGP QHEPAGGSGS FPRDPGGLDE VAMGEMEADV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGGGG AACGGTGCAC CAGGGACCTC ATGGTGCCCT TGGGGCCTCG ACTGCAGGCA 60
TTTCCTGAAG AACTCCTTCG ACAGCGGCCT GGGCACGATG GGTGTCCTGA ATACCTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021097--CPH_domain
IPR031222--CUL9
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM01337--APC10
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0000226--P:microtubule cytoskeleton organization
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003458	Anas platyrhynchos	56.06	4.00e-99	357.00
IUUC-Cfa-020119	Canis familiaris	92.14	0.00e+00	1062.00
IUUC-Cho-024879	Choloepus hoffmanni	84.17	5.00e-135	476.00
IUUC-Dno-028904	Dasypus novemcinctus	92.96	0.00e+00	1038.00
IUUC-Ete-032516	Echinops telfairi	82.86	0.00e+00	810.00
IUUC-Gmo-038795	Gadus morhua	49.73	0.00e+00	949.00
IUUC-Gga-040154	Gallus gallus	52.10	6.00e-101	363.00
IUUC-Meu-056198	Macropus eugenii	64.70	0.00e+00	1385.00
IUUC-Mga-059683	Meleagris gallopavo	52.72	6.00e-101	360.00
IUUC-Mdo-062018	Monodelphis domestica	68.08	0.00e+00	1507.00
IUUC-Mlu-067473	Myotis lucifugus	89.35	0.00e+00	974.00
IUUC-Nle-069292	Nomascus leucogenys	92.96	0.00e+00	1047.00
IUUC-Pfo-096773	Poecilia formosa	46.88	3.00e-137	484.00
IUUC-Pca-100539	Procavia capensis	87.67	0.00e+00	1029.00
IUUC-Sha-106896	Sarcophilus harrisii	78.82	0.00e+00	639.00
IUUC-Sar-113132	Sorex araneus	83.89	0.00e+00	719.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence