iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098414

Ensembl Protein ID

ENSPPYP00000009095.2

UniProt Accession

H2NT28; H2NT28_PONAB

Genbank Protein ID

ENSPPYP00000009095

Protein Name

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

Genbank Nucleotide ID

ABGA01048692

Gene Name

TNFAIP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000008088.2	ENSPPYT00000009465.2	ENSPPYP00000009095.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.80e-07	31.5	29	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmele.esksklmveikdvqpevfrallkFlYtgklde 67
            v+l+vgg+ + ++   L+++  +++a+f++ +e  +++++ + i+ +  ++f ++l++l+ +++++
   Q: 29   YVQLNVGGSLYYTTVRALTRHDTMLKAMFSGRMEvLTDKEGWILID-RCGKHFGTILNYLRDDTITL 94
           599********************************9999******9.**************999876 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSGDTCLCPA SGAKPKLSGF KGGGLGNKYV QLNVGGSLYY TTVRALTRHD TMLKAMFSGR 60
MEVLTDKEGW ILIDRCGKHF GTILNYLRDD TITLPQNRQE IKELMAEAKY YLIQGLVNMC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTATGCG TGCAGGGACT TGTAGTCTCA GACTCCCCAG CCGGCTGGGC TGGGCCGCAC 60
TCCGGGCGGA GTCGGCGAGC GCAGGATGTG AGCTCACAGC TTGGGACTGC TGGTGGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR003131--T1-type_BTB

PROSITE

PS50097--BTB

Pfam

PF02214--BTB_2

SMART

SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005768--C:endosome
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0016477--P:cell migration
GO:0009790--P:embryo development
GO:0006955--P:immune response
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization
GO:0043149--P:stress fiber assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001724	Ailuropoda melanoleuca	95.89	0.00e+00	627.00
IUUC-Apl-003702	Anas platyrhynchos	89.52	9.00e-165	572.00
IUUC-Aca-004408	Anolis carolinensis	81.01	3.00e-143	500.00
IUUC-Afl-008662	Aspergillus flavus	33.90	5.80e-02	31.60
IUUC-Afu-008834	Aspergillus fumigatus	32.50	1.00e+00	27.30
IUUC-Ang-009546	Aspergillus niger	32.20	4.80e-02	31.20
IUUC-Ame-010738	Astyanax mexicanus	75.35	5.00e-119	420.00
IUUC-Bta-013551	Bos taurus	96.52	3.00e-170	590.00
IUUC-Cja-019122	Callithrix jacchus	98.10	0.00e+00	640.00
IUUC-Cfa-020193	Canis familiaris	97.78	0.00e+00	639.00
IUUC-Cpo-022024	Cavia porcellus	96.20	0.00e+00	631.00
IUUC-Csa-024138	Chlorocebus sabaeus	98.42	0.00e+00	642.00
IUUC-Dno-029163	Dasypus novemcinctus	96.20	0.00e+00	633.00
IUUC-Dor-030970	Dipodomys ordii	97.15	0.00e+00	635.00
IUUC-Eca-034114	Equus caballus	97.15	0.00e+00	636.00
IUUC-Eeu-034709	Erinaceus europaeus	95.89	2.00e-180	624.00
IUUC-Fca-036397	Felis catus	96.84	4.00e-171	593.00
IUUC-Fal-037588	Ficedula albicollis	89.81	6.00e-166	576.00
IUUC-Gga-040445	Gallus gallus	89.17	3.00e-164	570.00
IUUC-Ggo-045312	Gorilla gorilla	98.42	0.00e+00	642.00
IUUC-Hsa-046091	Homo sapiens	98.42	0.00e+00	642.00
IUUC-Itr-048608	Ictidomys tridecemlineatus	96.52	0.00e+00	633.00
IUUC-Lch-049970	Latimeria chalumnae	87.46	2.00e-164	571.00
IUUC-Laf-054286	Loxodonta africana	96.20	0.00e+00	631.00
IUUC-Meu-056850	Macropus eugenii	87.15	1.00e-151	528.00
IUUC-Mga-060119	Meleagris gallopavo	91.74	2.00e-129	454.00
IUUC-Mdo-061847	Monodelphis domestica	93.10	5.00e-165	573.00
IUUC-Mmu-063130	Mus musculus	95.57	0.00e+00	628.00
IUUC-Mpu-066060	Mustela putorius furo	97.15	0.00e+00	636.00
IUUC-Mlu-067951	Myotis lucifugus	97.78	0.00e+00	639.00
IUUC-Nle-069523	Nomascus leucogenys	98.42	0.00e+00	642.00
IUUC-Opr-070426	Ochotona princeps	96.20	0.00e+00	631.00
IUUC-Ont-072156	Oreochromis niloticus	68.29	3.00e-126	444.00
IUUC-Oan-073164	Ornithorhynchus anatinus	82.42	1.00e-68	251.00
IUUC-Ocu-074319	Oryctolagus cuniculus	97.15	0.00e+00	637.00
IUUC-Oga-088279	Otolemur garnettii	96.52	0.00e+00	636.00
IUUC-Oar-089368	Ovis aries	96.84	0.00e+00	635.00
IUUC-Ptr-091204	Pan troglodytes	98.10	2.00e-174	604.00
IUUC-Pan-092880	Papio anubis	98.41	0.00e+00	640.00
IUUC-Psi-093768	Pelodiscus sinensis	88.82	2.00e-164	571.00
IUUC-Pca-100380	Procavia capensis	91.46	2.00e-170	591.00
IUUC-Pva-102366	Pteropus vampyrus	96.84	0.00e+00	634.00
IUUC-Pgr-103695	Puccinia graminis	24.86	3.00e-03	38.10
IUUC-Rno-104902	Rattus norvegicus	94.62	0.00e+00	625.00
IUUC-Sha-106996	Sarcophilus harrisii	92.48	7.00e-165	572.00
IUUC-Ssc-116300	Sus scrofa	97.15	0.00e+00	636.00
IUUC-Tgu-116738	Taeniopygia guttata	89.17	6.00e-165	572.00
IUUC-Tru-117840	Takifugu rubripes	71.66	2.00e-112	398.00
IUUC-Tsy-119370	Tarsius syrichta	78.95	3.00e-107	381.00
IUUC-Tni-119857	Tetraodon nigroviridis	69.94	6.00e-126	443.00
IUUC-Tbe-127709	Tupaia belangeri	96.52	0.00e+00	630.00
IUUC-Ttr-129110	Tursiops truncatus	96.52	0.00e+00	635.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence