iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074358

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02060529

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007636.2	ENSOCUT00000007636.2	ENSOCUP00000006605.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	2.90e-11	42.7	191	217
ULD/UDP/UBQ/UBQ_Other	1.80e-06	27.8	61	121

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 191  VGWQCPGCTFINKPTRPGCEMCCRARP 217
           68************************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++
   Q: 61   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPVLQQWVI-GQRLaRDQETLHSHGVR 121
           5666665577777889****************************.55555*********996 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MDEKTKKAEE MALSLARAVA GGDEQAAVKC ATWLAEQRVP LRMQLKPEAS PTKDIRWLWV 60
SVEDAQMHTV TIWLTVRPDM TVASLKDMVF LDYGFPPVLQ QWVIGQRLAR DQETLHSHGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAGA AGACCAAGAA AGGTGGGCGC GGCGTGGGGC CTCGGGCGGG ACCCTGCCTT 60
GCCTACGCAG AAGGGCCTGG AGACGGGGCT CCCGCCCGCC CTCGGCCCAC CTGCCCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	81.19	0.00e+00	751.00
IUUC-Apl-003627	Anas platyrhynchos	62.16	2.00e-18	82.80
IUUC-Aca-004507	Anolis carolinensis	56.37	2.00e-133	468.00
IUUC-Ame-011008	Astyanax mexicanus	46.42	1.00e-120	426.00
IUUC-Bta-013247	Bos taurus	81.77	0.00e+00	772.00
IUUC-Cja-018880	Callithrix jacchus	83.08	0.00e+00	795.00
IUUC-Cfa-020477	Canis familiaris	81.38	0.00e+00	778.00
IUUC-Cpo-021558	Cavia porcellus	81.96	0.00e+00	764.00
IUUC-Csa-024129	Chlorocebus sabaeus	83.08	0.00e+00	764.00
IUUC-Cin-025630	Ciona intestinalis	35.80	9.00e-69	254.00
IUUC-Csv-026069	Ciona savignyi	41.54	6.00e-58	217.00
IUUC-Dre-027591	Danio rerio	45.87	1.00e-119	423.00
IUUC-Dno-029015	Dasypus novemcinctus	80.42	0.00e+00	758.00
IUUC-Dor-030313	Dipodomys ordii	73.87	0.00e+00	652.00
IUUC-Ete-032908	Echinops telfairi	77.71	0.00e+00	729.00
IUUC-Eca-034295	Equus caballus	68.57	0.00e+00	635.00
IUUC-Eeu-034454	Erinaceus europaeus	81.08	1.00e-107	383.00
IUUC-Fca-036380	Felis catus	83.49	0.00e+00	785.00
IUUC-Fal-037440	Ficedula albicollis	58.62	1.00e-15	73.90
IUUC-Gmo-038561	Gadus morhua	46.52	3.00e-93	335.00
IUUC-Gga-040198	Gallus gallus	41.29	3.00e-31	129.00
IUUC-Gac-041319	Gasterosteus aculeatus	46.33	2.00e-110	392.00
IUUC-Ggo-044456	Gorilla gorilla	55.14	3.00e-121	428.00
IUUC-Hsa-045738	Homo sapiens	83.27	0.00e+00	761.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	83.46	0.00e+00	765.00
IUUC-Lch-050269	Latimeria chalumnae	42.65	4.00e-113	402.00
IUUC-Loc-052776	Lepisosteus oculatus	52.62	2.00e-81	296.00
IUUC-Laf-054269	Loxodonta africana	80.04	0.00e+00	757.00
IUUC-Mcc-055669	Macaca mulatta	83.46	0.00e+00	768.00
IUUC-Meu-055912	Macropus eugenii	46.51	2.00e-20	93.20
IUUC-Mga-059615	Meleagris gallopavo	54.69	3.00e-17	79.00
IUUC-Mmr-061562	Microcebus murinus	83.12	0.00e+00	681.00
IUUC-Mdo-062263	Monodelphis domestica	69.83	0.00e+00	673.00
IUUC-Mmu-064325	Mus musculus	82.66	0.00e+00	756.00
IUUC-Mpu-066385	Mustela putorius furo	82.73	0.00e+00	781.00
IUUC-Mlu-067000	Myotis lucifugus	81.54	0.00e+00	756.00
IUUC-Nle-069812	Nomascus leucogenys	82.89	0.00e+00	759.00
IUUC-Opr-070575	Ochotona princeps	78.04	3.00e-84	305.00
IUUC-Ont-072405	Oreochromis niloticus	44.31	1.00e-114	406.00
IUUC-Ola-086403	Oryzias latipes	47.14	5.00e-120	424.00
IUUC-Oga-087986	Otolemur garnettii	81.96	0.00e+00	748.00
IUUC-Oar-089600	Ovis aries	79.65	0.00e+00	773.00
IUUC-Ptr-091224	Pan troglodytes	83.08	0.00e+00	760.00
IUUC-Pan-092739	Papio anubis	83.46	0.00e+00	768.00
IUUC-Pma-094407	Petromyzon marinus	41.68	3.00e-104	372.00
IUUC-Pfo-097161	Poecilia formosa	43.94	2.00e-109	389.00
IUUC-Pab-098627	Pongo abelii	83.08	0.00e+00	754.00
IUUC-Pca-100641	Procavia capensis	80.61	0.00e+00	706.00
IUUC-Pva-102670	Pteropus vampyrus	81.96	0.00e+00	761.00
IUUC-Rno-105504	Rattus norvegicus	82.82	0.00e+00	754.00
IUUC-Sha-107342	Sarcophilus harrisii	69.26	0.00e+00	692.00
IUUC-Sar-113425	Sorex araneus	91.06	1.00e-96	346.00
IUUC-Ssc-115904	Sus scrofa	68.85	3.00e-68	250.00
IUUC-Tru-117607	Takifugu rubripes	44.86	3.00e-110	392.00
IUUC-Tni-119873	Tetraodon nigroviridis	43.87	2.00e-116	412.00
IUUC-Tvi-122402	Trichoderma virens	28.17	6.00e-03	35.00
IUUC-Tbe-127578	Tupaia belangeri	83.41	0.00e+00	625.00
IUUC-Ttr-129107	Tursiops truncatus	81.57	0.00e+00	739.00
IUUC-Vpa-130353	Vicugna pacos	91.09	1.00e-115	409.00
IUUC-Xtr-132168	Xenopus tropicalis	42.35	1.00e-66	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence