iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106607

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01103982

Gene Name

TTC3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013708.1	ENSSHAT00000016233.1	ENSSHAP00000016100.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-07	30.4	1444	1484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf.kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e++ +++++ ++CgH+fh+ C+++w       + + +CP+Cr
   Q: 1444 CIICYEELnQEHVCEMDCGHQFHKWCIEQW------LKEQSTCPTCR 1484
           ********7555999***************......**********8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

GHNPKFKDSS LQLNLQIDLQ SLLDKQFSKS SRAVQQDFAI LIKMLQSLIE EGCTALMDQH 60
CRSAAKAFSR LLSDLDPNKL KQLNLALINY VLVIYGYAIS LLGIGMPEEL SEAEYQFKRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCATAATC CTAAATTTAA AGGAAAATCA AAGAATAAAA GCGATGATGT AGGAAAACCA 60
AGGTATGAAT TTTTCTGATG TGTTAAGGAA TCAAATTATA AATTATTATG TTTCTTTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR011990--TPR-like_helical_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00619--CARD
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0070936--P:protein K48-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003622	Anas platyrhynchos	46.91	0.00e+00	1179.00
IUUC-Aca-004579	Anolis carolinensis	39.45	1.00e-79	290.00
IUUC-Ame-011167	Astyanax mexicanus	40.64	5.00e-138	486.00
IUUC-Bta-012916	Bos taurus	61.06	0.00e+00	860.00
IUUC-Cja-019100	Callithrix jacchus	61.32	0.00e+00	847.00
IUUC-Cfa-020974	Canis familiaris	60.30	0.00e+00	865.00
IUUC-Cpo-022435	Cavia porcellus	43.74	0.00e+00	800.00
IUUC-Csa-023245	Chlorocebus sabaeus	61.61	0.00e+00	877.00
IUUC-Cho-024822	Choloepus hoffmanni	56.63	0.00e+00	697.00
IUUC-Dre-027805	Danio rerio	39.65	2.00e-123	437.00
IUUC-Dno-029413	Dasypus novemcinctus	57.49	0.00e+00	763.00
IUUC-Dor-030670	Dipodomys ordii	60.84	0.00e+00	763.00
IUUC-Ete-032367	Echinops telfairi	40.06	6.00e-59	223.00
IUUC-Eca-033891	Equus caballus	61.84	0.00e+00	870.00
IUUC-Fca-035889	Felis catus	49.05	0.00e+00	1215.00
IUUC-Fal-037399	Ficedula albicollis	43.46	0.00e+00	1056.00
IUUC-Gmo-039198	Gadus morhua	35.04	3.00e-16	75.90
IUUC-Gga-040490	Gallus gallus	55.12	0.00e+00	789.00
IUUC-Gac-042289	Gasterosteus aculeatus	36.91	6.00e-23	99.40
IUUC-Ggo-045441	Gorilla gorilla	61.87	0.00e+00	897.00
IUUC-Hsa-045811	Homo sapiens	61.87	0.00e+00	895.00
IUUC-Itr-048367	Ictidomys tridecemlineatus	49.46	2.00e-58	220.00
IUUC-Lch-049809	Latimeria chalumnae	47.83	1.00e-154	540.00
IUUC-Loc-052533	Lepisosteus oculatus	44.17	5.00e-160	559.00
IUUC-Laf-053785	Loxodonta africana	50.82	0.00e+00	676.00
IUUC-Mcc-054801	Macaca mulatta	61.32	0.00e+00	890.00
IUUC-Mga-059963	Meleagris gallopavo	49.05	0.00e+00	897.00
IUUC-Mmr-060707	Microcebus murinus	61.53	0.00e+00	867.00
IUUC-Mdo-062718	Monodelphis domestica	78.06	0.00e+00	2103.00
IUUC-Mmu-064257	Mus musculus	60.76	0.00e+00	841.00
IUUC-Mpu-066020	Mustela putorius furo	61.52	0.00e+00	859.00
IUUC-Mlu-067023	Myotis lucifugus	61.42	0.00e+00	841.00
IUUC-Nle-069965	Nomascus leucogenys	61.79	0.00e+00	897.00
IUUC-Opr-070629	Ochotona princeps	47.53	3.00e-124	440.00
IUUC-Ont-072604	Oreochromis niloticus	40.62	1.00e-124	442.00
IUUC-Oan-072830	Ornithorhynchus anatinus	56.67	0.00e+00	1352.00
IUUC-Ocu-073774	Oryctolagus cuniculus	60.91	0.00e+00	887.00
IUUC-Ola-086847	Oryzias latipes	38.60	2.00e-120	426.00
IUUC-Oga-088372	Otolemur garnettii	59.35	0.00e+00	831.00
IUUC-Oar-090039	Ovis aries	58.47	0.00e+00	818.00
IUUC-Ptr-091171	Pan troglodytes	61.87	0.00e+00	892.00
IUUC-Pan-091926	Papio anubis	59.95	0.00e+00	887.00
IUUC-Psi-093680	Pelodiscus sinensis	52.10	0.00e+00	1189.00
IUUC-Pab-098120	Pongo abelii	61.74	0.00e+00	895.00
IUUC-Ppe-101935	Prunus persica	44.64	2.00e-09	54.30
IUUC-Pva-102424	Pteropus vampyrus	54.84	8.00e-120	426.00
IUUC-Pgr-103393	Puccinia graminis	40.62	4.00e-08	51.60
IUUC-Pyt-104680	Pyrenophora triticirepentis	39.68	3.00e-09	55.80
IUUC-Rno-105101	Rattus norvegicus	60.94	0.00e+00	867.00
IUUC-Sar-113589	Sorex araneus	57.09	0.00e+00	766.00
IUUC-Ssc-115530	Sus scrofa	62.23	0.00e+00	892.00
IUUC-Tgu-116671	Taeniopygia guttata	51.27	0.00e+00	645.00
IUUC-Tru-118283	Takifugu rubripes	36.13	1.00e-109	391.00
IUUC-Tsy-118872	Tarsius syrichta	56.53	0.00e+00	832.00
IUUC-Tme-126989	Tuber melanosporum	47.46	2.00e-10	61.20
IUUC-Tbe-127996	Tupaia belangeri	56.01	7.00e-171	595.00
IUUC-Ttr-128379	Tursiops truncatus	60.16	0.00e+00	825.00
IUUC-Vpa-130372	Vicugna pacos	57.76	0.00e+00	813.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence