iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088808

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03165220

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000013692.2	ENSOGAT00000013694.2	ENSOGAP00000012263.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.60e-08	34.3	10	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +      f+CP+Cr
   Q: 10   CPICCSLFDD-PRVLPCSHNFCKKCLEGIfegnVRNSLWRPSPFKCPTCR 58
           ********99.**************966667666666679999******8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MELLEEDLTC PICCSLFDDP RVLPCSHNFC KKCLEGIFEG NVRNSLWRPS PFKCPTCRKE 60
TSATGVNSLQ VNYSLKGIVE KYNKIKVSPK MPVCKGHLGQ PLNIFCLTDM QLICGVCATC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCTGC TTGAAGAAGA TCTCACTTGC CCAATTTGCT GCAGCCTGTT TGATGATCCC 60
CGAGTTTTGC CTTGCTCCCA CAACTTCTGC AAAAAATGTT TAGAAGGTAT CTTCGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	93.86	0.00e+00	741.00
IUUC-Apl-004168	Anas platyrhynchos	76.72	0.00e+00	633.00
IUUC-Aca-004395	Anolis carolinensis	69.85	5.00e-165	573.00
IUUC-Ame-011325	Astyanax mexicanus	46.13	3.00e-67	249.00
IUUC-Bta-012613	Bos taurus	93.12	0.00e+00	738.00
IUUC-Cja-018856	Callithrix jacchus	93.86	0.00e+00	769.00
IUUC-Cfa-021019	Canis familiaris	94.35	0.00e+00	735.00
IUUC-Cpo-021845	Cavia porcellus	91.65	0.00e+00	728.00
IUUC-Csa-023380	Chlorocebus sabaeus	93.61	0.00e+00	743.00
IUUC-Cho-024733	Choloepus hoffmanni	83.71	2.00e-91	328.00
IUUC-Dre-028675	Danio rerio	60.20	2.00e-109	389.00
IUUC-Dno-030018	Dasypus novemcinctus	91.42	0.00e+00	724.00
IUUC-Dor-030599	Dipodomys ordii	90.26	7.00e-127	446.00
IUUC-Dse-031522	Dothistroma septosporum	32.89	1.00e-05	43.90
IUUC-Ete-033134	Echinops telfairi	88.24	0.00e+00	725.00
IUUC-Eca-033931	Equus caballus	95.09	0.00e+00	743.00
IUUC-Eeu-034903	Erinaceus europaeus	91.65	0.00e+00	727.00
IUUC-Fca-035642	Felis catus	93.86	0.00e+00	730.00
IUUC-Fal-037108	Ficedula albicollis	77.21	0.00e+00	635.00
IUUC-Gga-040903	Gallus gallus	76.00	5.00e-177	613.00
IUUC-Ggo-044635	Gorilla gorilla	93.37	0.00e+00	745.00
IUUC-Hsa-046345	Homo sapiens	93.37	0.00e+00	744.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	91.71	0.00e+00	711.00
IUUC-Lch-050599	Latimeria chalumnae	60.70	8.00e-137	479.00
IUUC-Loc-052378	Lepisosteus oculatus	63.40	5.00e-118	416.00
IUUC-Laf-053332	Loxodonta africana	91.67	0.00e+00	732.00
IUUC-Mcc-054705	Macaca mulatta	92.87	0.00e+00	741.00
IUUC-Meu-056825	Macropus eugenii	84.80	0.00e+00	691.00
IUUC-Mga-059528	Meleagris gallopavo	75.00	1.00e-180	625.00
IUUC-Mmr-060688	Microcebus murinus	97.30	0.00e+00	762.00
IUUC-Mdo-061882	Monodelphis domestica	84.07	0.00e+00	695.00
IUUC-Mmu-064352	Mus musculus	88.70	0.00e+00	737.00
IUUC-Mpu-066712	Mustela putorius furo	93.14	0.00e+00	680.00
IUUC-Mlu-068093	Myotis lucifugus	92.14	0.00e+00	722.00
IUUC-Nle-069310	Nomascus leucogenys	93.37	0.00e+00	741.00
IUUC-Ont-071759	Oreochromis niloticus	59.28	1.00e-110	393.00
IUUC-Oan-073673	Ornithorhynchus anatinus	80.39	0.00e+00	667.00
IUUC-Ocu-074192	Oryctolagus cuniculus	93.12	0.00e+00	739.00
IUUC-Ola-087424	Oryzias latipes	58.96	2.00e-109	388.00
IUUC-Oar-089553	Ovis aries	92.63	0.00e+00	736.00
IUUC-Ptr-090518	Pan troglodytes	94.10	0.00e+00	753.00
IUUC-Pan-092781	Papio anubis	92.63	0.00e+00	740.00
IUUC-Psi-093914	Pelodiscus sinensis	75.55	6.00e-180	623.00
IUUC-Pma-094162	Petromyzon marinus	34.06	7.00e-44	170.00
IUUC-Pfo-096346	Poecilia formosa	56.92	3.00e-108	384.00
IUUC-Pca-100914	Procavia capensis	90.44	0.00e+00	741.00
IUUC-Pva-102728	Pteropus vampyrus	93.12	0.00e+00	735.00
IUUC-Rno-105922	Rattus norvegicus	88.70	0.00e+00	684.00
IUUC-Sha-107124	Sarcophilus harrisii	84.56	0.00e+00	704.00
IUUC-Sar-113607	Sorex araneus	89.68	0.00e+00	698.00
IUUC-Ssc-116355	Sus scrofa	94.10	0.00e+00	745.00
IUUC-Tgu-116476	Taeniopygia guttata	76.96	0.00e+00	633.00
IUUC-Tru-118737	Takifugu rubripes	59.28	8.00e-112	396.00
IUUC-Tsy-118908	Tarsius syrichta	94.84	0.00e+00	746.00
IUUC-Tni-119737	Tetraodon nigroviridis	33.55	2.00e-49	189.00
IUUC-Tbe-127258	Tupaia belangeri	96.31	0.00e+00	758.00
IUUC-Ttr-128921	Tursiops truncatus	33.66	3.00e-51	196.00
IUUC-Vpa-130138	Vicugna pacos	94.84	0.00e+00	745.00
IUUC-Xtr-132100	Xenopus tropicalis	59.31	5.00e-137	480.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence