iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068237

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02045470

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000008753.2	ENSMLUT00000008745.2	ENSMLUP00000007968.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.00e-20	71.0	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-09	36.3	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es+  ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESR-DDTVNFQDnLHPEVLELLLDFAYSSRIVLNE 114
           7*************************************.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L++ a +++l hF+
   Q: 146  PSNCLGMMLLSDAHQCRRLHELAWRMCLAHFE 177
           89*****************************5 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MSVSVHETRK SRSSTGSMNI TLFHKASHPD CVLAHLNTLR KHCMFTDVTL WAGDRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESRDDTVNFQ DNLHPEVLEL LLDFAYSSRI VLNEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTCA GCGTCCACGA GACCCGCAAG TCGCGGAGCA GCACGGGCTC CATGAACATC 60
ACGCTCTTCC ACAAGGCGTC GCACCCCGAC TGCGTGCTGG CCCACCTCAA CACGCTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	93.89	0.00e+00	1169.00
IUUC-Apl-003543	Anas platyrhynchos	87.97	0.00e+00	1070.00
IUUC-Aca-004729	Anolis carolinensis	85.57	0.00e+00	1057.00
IUUC-Ame-011020	Astyanax mexicanus	83.87	0.00e+00	1023.00
IUUC-Bta-012955	Bos taurus	93.21	0.00e+00	1158.00
IUUC-Cja-018839	Callithrix jacchus	93.55	0.00e+00	1165.00
IUUC-Cfa-020224	Canis familiaris	93.89	0.00e+00	1166.00
IUUC-Cpo-021593	Cavia porcellus	92.53	0.00e+00	1106.00
IUUC-Csa-023276	Chlorocebus sabaeus	94.06	0.00e+00	1170.00
IUUC-Dre-028053	Danio rerio	84.21	0.00e+00	992.00
IUUC-Dno-029287	Dasypus novemcinctus	93.89	0.00e+00	1157.00
IUUC-Dor-030908	Dipodomys ordii	85.40	0.00e+00	1036.00
IUUC-Fca-035897	Felis catus	93.72	0.00e+00	1166.00
IUUC-Fal-037036	Ficedula albicollis	88.12	0.00e+00	1077.00
IUUC-Gmo-039345	Gadus morhua	84.38	0.00e+00	992.00
IUUC-Gga-040404	Gallus gallus	87.78	0.00e+00	1075.00
IUUC-Gac-042447	Gasterosteus aculeatus	84.04	0.00e+00	1008.00
IUUC-Ggo-045060	Gorilla gorilla	93.89	0.00e+00	1169.00
IUUC-Hsa-046494	Homo sapiens	93.89	0.00e+00	1169.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	93.89	0.00e+00	1164.00
IUUC-Lch-050211	Latimeria chalumnae	84.35	0.00e+00	1027.00
IUUC-Loc-052578	Lepisosteus oculatus	83.87	0.00e+00	1029.00
IUUC-Lma-053168	Leptosphaeria maculans	29.79	7.00e-05	41.60
IUUC-Laf-053498	Loxodonta africana	93.21	0.00e+00	1112.00
IUUC-Mcc-055033	Macaca mulatta	94.23	0.00e+00	1171.00
IUUC-Meu-056893	Macropus eugenii	89.98	0.00e+00	1124.00
IUUC-Mga-060025	Meleagris gallopavo	87.95	0.00e+00	1077.00
IUUC-Mmr-060658	Microcebus murinus	93.89	0.00e+00	1172.00
IUUC-Mdo-062667	Monodelphis domestica	89.98	0.00e+00	1123.00
IUUC-Mmu-063125	Mus musculus	91.17	0.00e+00	1106.00
IUUC-Mpu-066209	Mustela putorius furo	94.06	0.00e+00	1170.00
IUUC-Nle-069454	Nomascus leucogenys	93.83	0.00e+00	1154.00
IUUC-Ont-072138	Oreochromis niloticus	83.70	0.00e+00	994.00
IUUC-Oan-073320	Ornithorhynchus anatinus	84.72	0.00e+00	1052.00
IUUC-Ocu-073765	Oryctolagus cuniculus	89.81	0.00e+00	1090.00
IUUC-Oga-088002	Otolemur garnettii	93.21	0.00e+00	1153.00
IUUC-Oar-089481	Ovis aries	93.04	0.00e+00	1158.00
IUUC-Ptr-091200	Pan troglodytes	93.89	0.00e+00	1168.00
IUUC-Psi-093884	Pelodiscus sinensis	86.93	0.00e+00	1064.00
IUUC-Pno-095143	Phaeosphaeria nodorum	27.64	5.00e-15	75.10
IUUC-Pva-102321	Pteropus vampyrus	93.55	0.00e+00	1163.00
IUUC-Rno-104835	Rattus norvegicus	90.66	0.00e+00	1103.00
IUUC-Sha-107528	Sarcophilus harrisii	89.30	0.00e+00	1118.00
IUUC-Ssc-116161	Sus scrofa	94.40	0.00e+00	1171.00
IUUC-Tgu-116569	Taeniopygia guttata	87.95	0.00e+00	1072.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.30	0.00e+00	864.00
IUUC-Ttr-129297	Tursiops truncatus	94.57	0.00e+00	1170.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence