iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027521

UUCD1 version

UUC-DaR-01295

Ensembl Protein ID

ENSDARP00000017859.8

UniProt Accession

Q7ZTX2; Q7ZTX2_DANRE

Genbank Protein ID

AAH52124.1; AAH66729.1

Protein Name

WD repeat domain 5; Wdr5 protein

Genbank Nucleotide ID

FP102053; BC066729

Gene Name

wdr5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000016903.9	ENSDART00000019750.8	ENSDARP00000017859.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-58	193.0	127	166
UBD/Beta-Prp	3.60e-88	296.5	40	332

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH++ v+c++f +  +l+vsGs D ++++WD++tg++lk+
   Q: 127  GHSNYVFCCNFnPQsNLIVSGSFDESVRIWDVKTGKCLKT 166
           8***********666**********************986 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           tl gh k+v + vkfsp++++la++s+d+ ik+w + +gk+ +++sgh+ ++++v +s+d+++lv++s+D+t+k+wd+s+gkc+ tlkg
   Q: 40   TLAGHTKAVSS-VKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKG 127
           67777776666.***************************************************************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h+++v +++f+p+++ +vsGs d+ +r+wd++tg+cl+ tl  h++ v+ v+++ dg+l+vs+s+D+ +r+Wd ++g++l+tl  ++++
   Q: 128  HSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK-TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNP 215
           **************************************.********************************************999*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs...pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +v  ++f++ngk+++++ ld+t+klwd+++g+c++t++gh++  +++ +      ++++vsgs+D+ ++iW+l++++++++lq+h + v
   Q: 216  PVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANfsvTGGKWIVSGSEDNMVYIWNLQTKEIVQKLQGHTDVV 304
           **********************************************98887899*********************************** PP
   S: 268  isvavlsfgdnvlvlgse..dskvniwkl 294
           is a+ ++++n++++++   d+++++wk 
   Q: 305  ISTAC-HPTENIIASAALenDKTIKLWKS 332
           *****.*******9998888*******96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MATEEKKPDT EATKTQPASA ASASQSKSAP VKPNYTLKFT LAGHTKAVSS VKFSPSGEWL 60
ASSSADKLIK IWGAYDGKFE KTISGHKLGI SDVAWSSDSN LLVSASDDKT LKIWDVSSGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCACATTA AGATGGCGCG CAGCTAACAG AGTTAGCATC CACGCTTAGC GTTTCTGCAC 60
CTTCTCGAGC CTCTTTTTAT TGACTCGCGT CAATCTATCA TACACAGAGA TACGCTGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0060271--P:cilium assembly

KEGG

dre:406372

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000502	Aegilops tauschii	53.02	1.00e-89	323.00
IUUC-Aml-002420	Ailuropoda melanoleuca	92.73	4.00e-179	620.00
IUUC-Atr-002439	Amborella trichopoda	70.10	2.00e-129	455.00
IUUC-Apl-003436	Anas platyrhynchos	88.92	1.00e-166	578.00
IUUC-Aca-004259	Anolis carolinensis	95.51	0.00e+00	631.00
IUUC-Aly-005723	Arabidopsis lyrata	64.45	2.00e-116	412.00
IUUC-Ath-007308	Arabidopsis thaliana	65.45	1.00e-116	412.00
IUUC-Ago-007915	Ashbya gossypii	37.58	3.00e-45	175.00
IUUC-Acl-008045	Aspergillus clavatus	45.95	3.00e-83	302.00
IUUC-Afl-008596	Aspergillus flavus	44.66	3.00e-80	292.00
IUUC-Afu-009074	Aspergillus fumigatus	46.75	5.00e-83	301.00
IUUC-Ani-009318	Aspergillus nidulans	50.00	1.00e-82	300.00
IUUC-Ang-009775	Aspergillus niger	45.63	1.00e-82	300.00
IUUC-Aor-010222	Aspergillus oryzae	44.66	2.00e-80	293.00
IUUC-Ate-010583	Aspergillus terreus	48.75	2.00e-80	293.00
IUUC-Ame-011349	Astyanax mexicanus	100.00	2.00e-180	624.00
IUUC-Bgr-011968	Blumeria graminis	50.33	2.00e-84	306.00
IUUC-Bta-013016	Bos taurus	98.05	5.00e-179	619.00
IUUC-Bci-013948	Botrytis cinerea	50.82	1.00e-84	307.00
IUUC-Bdi-014263	Brachypodium distachyon	62.13	1.00e-119	422.00
IUUC-Bol-015900	Brassica oleracea	62.50	3.00e-113	401.00
IUUC-Bra-017143	Brassica rapa	62.17	3.00e-114	404.00
IUUC-Cel-018355	Caenorhabditis elegans	72.24	4.00e-132	464.00
IUUC-Cja-019936	Callithrix jacchus	92.73	4.00e-179	620.00
IUUC-Cfa-020596	Canis familiaris	92.73	4.00e-179	620.00
IUUC-Cpo-021318	Cavia porcellus	92.73	4.00e-179	620.00
IUUC-Cre-022935	Chlamydomonas reinhardtii	49.63	1.00e-79	290.00
IUUC-Csa-023053	Chlorocebus sabaeus	92.73	4.00e-179	620.00
IUUC-Cho-024642	Choloepus hoffmanni	81.68	4.00e-151	527.00
IUUC-Cin-025495	Ciona intestinalis	87.58	3.00e-167	581.00
IUUC-Csv-025988	Ciona savignyi	92.20	9.00e-164	569.00
IUUC-Cgl-026771	Colletotrichum gloeosporioides	33.12	2.00e-45	178.00
IUUC-Cne-027025	Cryptococcus neoformans	32.13	5.00e-53	201.00
IUUC-Cme-027119	Cyanidioschyzon merolae	53.44	5.00e-104	370.00
IUUC-Dno-029739	Dasypus novemcinctus	99.01	4.00e-178	617.00
IUUC-Dor-030966	Dipodomys ordii	99.02	7.00e-179	619.00
IUUC-Dse-031189	Dothistroma septosporum	48.91	1.00e-85	310.00
IUUC-Dme-031613	Drosophila melanogaster	95.05	5.00e-172	596.00
IUUC-Ete-033098	Echinops telfairi	82.78	2.00e-152	531.00
IUUC-Eca-033790	Equus caballus	92.73	4.00e-179	620.00
IUUC-Eeu-034805	Erinaceus europaeus	86.14	2.00e-149	521.00
IUUC-Fca-035901	Felis catus	92.73	4.00e-179	620.00
IUUC-Fal-037413	Ficedula albicollis	96.11	0.00e+00	633.00
IUUC-Fox-037876	Fusarium oxysporum	46.45	4.00e-58	218.00
IUUC-Gmo-039131	Gadus morhua	93.11	3.00e-177	613.00
IUUC-Ggr-040071	Gaeumannomyces graminis	40.48	2.00e-63	237.00
IUUC-Gga-040789	Gallus gallus	96.11	0.00e+00	633.00
IUUC-Gac-042634	Gasterosteus aculeatus	95.51	4.00e-177	613.00
IUUC-Gma-043692	Glycine max	66.34	6.00e-127	447.00
IUUC-Ggo-044443	Gorilla gorilla	92.73	4.00e-179	620.00
IUUC-Hsa-046290	Homo sapiens	92.73	4.00e-179	620.00
IUUC-Hvu-047077	Hordeum vulgare	58.49	3.00e-78	284.00
IUUC-Itr-048954	Ictidomys tridecemlineatus	92.73	4.00e-179	620.00
IUUC-Kpa-049404	Komagataella pastoris	45.42	2.00e-65	243.00
IUUC-Lch-049539	Latimeria chalumnae	92.73	2.00e-179	620.00
IUUC-Lpe-051082	Leersia perrieri	61.33	1.00e-118	419.00
IUUC-Loc-051743	Lepisosteus oculatus	100.00	2.00e-180	624.00
IUUC-Lma-053188	Leptosphaeria maculans	46.73	3.00e-85	309.00
IUUC-Laf-054432	Loxodonta africana	92.24	5.00e-176	610.00
IUUC-Mcc-055603	Macaca mulatta	92.73	4.00e-179	620.00
IUUC-Meu-056440	Macropus eugenii	91.80	2.00e-155	541.00
IUUC-Mor-056965	Magnaporthe oryzae	36.83	8.00e-67	248.00
IUUC-Mpo-057333	Magnaporthe poae	41.16	8.00e-61	228.00
IUUC-Mtr-057951	Medicago truncatula	65.58	3.00e-122	431.00
IUUC-Mla-058896	Melampsora laricipopulina	43.29	3.00e-72	265.00
IUUC-Mga-060046	Meleagris gallopavo	95.81	0.00e+00	632.00
IUUC-Mvi-060453	Microbotryum violaceum	48.90	6.00e-88	318.00
IUUC-Mmr-061020	Microcebus murinus	85.80	1.00e-168	585.00
IUUC-Mdo-062204	Monodelphis domestica	96.07	6.00e-175	606.00
IUUC-Mmu-063917	Mus musculus	92.73	4.00e-179	620.00
IUUC-Mac-065310	Musa acuminata	66.22	4.00e-122	431.00
IUUC-Mpu-066072	Mustela putorius furo	92.73	4.00e-179	620.00
IUUC-Mlu-068209	Myotis lucifugus	92.73	4.00e-179	620.00
IUUC-Nfi-068538	Neosartorya fischeri	46.43	2.00e-82	300.00
IUUC-Ncr-068651	Neurospora crassa	41.96	3.00e-72	266.00
IUUC-Nle-069383	Nomascus leucogenys	87.50	3.00e-152	531.00
IUUC-Opr-070937	Ochotona princeps	83.28	1.00e-141	495.00
IUUC-Ont-071458	Oreochromis niloticus	96.71	5.00e-179	620.00
IUUC-Oan-073597	Ornithorhynchus anatinus	99.02	1.00e-179	622.00
IUUC-Oba-075292	Oryza barthii	56.42	3.00e-99	354.00
IUUC-Obr-076723	Oryza brachyantha	54.90	1.00e-96	346.00
IUUC-Ogl-077251	Oryza glaberrima	60.06	3.00e-116	411.00
IUUC-Ogu-078882	Oryza glumaepatula	49.58	3.00e-102	365.00
IUUC-Oin-079601	Oryza indica	54.25	2.00e-111	395.00
IUUC-Olo-080976	Oryza longistaminata	62.95	3.00e-102	364.00
IUUC-Ome-081430	Oryza meridionalis	60.46	2.00e-116	412.00
IUUC-Oni-082182	Oryza nivara	49.18	7.00e-102	363.00
IUUC-Opu-083880	Oryza punctata	59.80	1.00e-115	409.00
IUUC-Oru-084935	Oryza rufipogon	53.65	1.00e-98	352.00
IUUC-Osa-085706	Oryza sativa	60.06	3.00e-116	411.00
IUUC-Ola-087134	Oryzias latipes	96.11	4.00e-179	620.00
IUUC-Olu-087660	Ostreococcus lucimarinus	42.50	4.00e-40	157.00
IUUC-Oga-088672	Otolemur garnettii	96.11	0.00e+00	632.00
IUUC-Oar-089860	Ovis aries	85.27	3.00e-152	530.00
IUUC-Ptr-091513	Pan troglodytes	92.73	4.00e-179	620.00
IUUC-Pan-092046	Papio anubis	92.73	4.00e-179	620.00
IUUC-Psi-093192	Pelodiscus sinensis	95.81	0.00e+00	633.00
IUUC-Pno-094881	Phaeosphaeria nodorum	48.04	3.00e-89	322.00
IUUC-Ppa-095367	Physcomitrella patens	72.58	3.00e-133	468.00
IUUC-Pfo-097434	Poecilia formosa	96.11	2.00e-178	618.00
IUUC-Pab-097773	Pongo abelii	92.79	9.00e-163	565.00
IUUC-Pop-099778	Populus trichocarpa	66.34	4.00e-121	427.00
IUUC-Pca-100281	Procavia capensis	76.22	4.00e-119	421.00
IUUC-Ppe-101341	Prunus persica	66.03	6.00e-123	433.00
IUUC-Pva-103020	Pteropus vampyrus	92.42	2.00e-178	618.00
IUUC-Pgr-103589	Puccinia graminis	39.27	1.00e-69	256.00
IUUC-Ptt-103745	Puccinia triticina	34.67	2.00e-36	146.00
IUUC-Pte-104153	Pyrenophora teres	51.59	3.00e-93	335.00
IUUC-Pyt-104712	Pyrenophora triticirepentis	52.06	3.00e-78	285.00
IUUC-Rno-105858	Rattus norvegicus	92.73	4.00e-179	620.00
IUUC-Sce-106243	Saccharomyces cerevisiae	34.78	2.00e-39	155.00
IUUC-Sha-107101	Sarcophilus harrisii	99.02	1.00e-178	619.00
IUUC-Sja-107858	Schizosaccharomyces japonicus	50.70	7.00e-68	251.00
IUUC-Spo-108117	Schizosaccharomyces pombe	47.53	3.00e-63	235.00
IUUC-Smo-109155	Selaginella moellendorffii	72.09	4.00e-131	461.00
IUUC-Sit-110688	Setaria italica	62.00	8.00e-119	419.00
IUUC-Sly-110891	Solanum lycopersicum	68.90	4.00e-126	444.00
IUUC-Stu-112365	Solanum tuberosum	68.90	4.00e-126	444.00
IUUC-Sbi-114284	Sorghum bicolor	62.00	6.00e-118	416.00
IUUC-Sre-115180	Sporisorium reilianum	42.57	8.00e-67	247.00
IUUC-Ssc-116204	Sus scrofa	99.01	2.00e-178	617.00
IUUC-Tgu-117172	Taeniopygia guttata	96.11	0.00e+00	633.00
IUUC-Tru-118320	Takifugu rubripes	91.62	2.00e-176	611.00
IUUC-Tni-120660	Tetraodon nigroviridis	92.79	4.00e-108	383.00
IUUC-Tca-121051	Theobroma cacao	67.86	2.00e-125	441.00
IUUC-Tre-122237	Trichoderma reesei	45.66	1.00e-83	303.00
IUUC-Tvi-122635	Trichoderma virens	45.86	2.00e-84	305.00
IUUC-Tae-123971	Triticum aestivum	60.86	2.00e-119	421.00
IUUC-Tur-126217	Triticum urartu	55.84	3.00e-76	278.00
IUUC-Tme-127061	Tuber melanosporum	59.87	4.00e-111	394.00
IUUC-Tbe-127488	Tupaia belangeri	87.50	2.00e-153	534.00
IUUC-Ttr-129309	Tursiops truncatus	90.91	7.00e-165	573.00
IUUC-Uma-129585	Ustilago maydis	41.64	8.00e-74	270.00
IUUC-Vda-129907	Verticillium dahliae	44.71	2.00e-78	286.00
IUUC-Vpa-130384	Vicugna pacos	84.68	1.00e-155	542.00
IUUC-Vvi-131269	Vitis vinifera	67.77	5.00e-119	420.00
IUUC-Xtr-131945	Xenopus tropicalis	95.81	0.00e+00	632.00
IUUC-Xma-132997	Xiphophorus maculatus	96.11	2.00e-178	618.00
IUUC-Yli-134418	Yarrowia lipolytica	42.62	6.00e-75	274.00
IUUC-Zma-135765	Zea mays	61.67	7.00e-117	413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence