iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022279

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02005935

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008696.3	ENSCPOT00000008774.2	ENSCPOP00000007808.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.70e-25	86.9	403	475
E3 adaptor/Cullin RING/DCX/DWD	1.80e-39	132.0	98	130
UBD/Beta-Prp	8.30e-59	199.2	3	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           ++p+ef+CpI+ elM+dPv++++G++y++ ++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 403  DIPDEFICPITRELMKDPVIASDGYSYEKDAMENWISKKKRTSPMTNLVLPSVVLTPNRTLKMAINRWLETHQ 475
           69********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           ++v+ ++f +d   l+sG+ Dgt+ +W++ +++
   Q: 98   SPVRVCRFsPDsSCLASGGADGTVVLWNTQSHK 130
           689999***88899**************87765 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht..lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           kl+++l +h++ v+++ fs++  +l+t+s D+ti++++ls++  + +  lk h++ v ++ fspsg+ l+s s d t  +w  ++gq l
   Q: 3    KLIHTLADHSDDVNCCAFSSS--LLATCSLDKTIRLYSLSNFAELPHspLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWSAHSGQTL 89
           789******************..9****************88765442389************************************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
             ++++  + v++ +++pd+++l+sG++D+tv lW+ ++ kl r  +  +++s    +f++ng+ +v+gs  g+++lwd +   c+++ 
   Q: 90   AVMEQPGGSPVRVCRFSPDSSCLASGGADGTVVLWNTQSHKLYRCGSV-KDGSLVACAFSPNGNLFVTGSSCGDLTLWDDKMR-CLHSE 176
           *9999999*********************************9999987.99*****************************655.***** PP
   S: 219  nghtdnvksvrfsp 232
           ++h+  +++ +fs+
   Q: 177  KAHDLGITCCDFSS 190
           *********99985 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MVKLIHTLAD HSDDVNCCAF SSSLLATCSL DKTIRLYSLS NFAELPHSPL KFHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WSAHSGQTLA VMEQPGGSPV RVCRFSPDSS CLASGGADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAT TAATTCACAC CTTAGCTGAT CATAGTGATG ATGTCAACTG CTGTGCCTTC 60
TCTTCTTCAC TGTTGGCTAC TTGTTCCTTG GACAAAACAA TTCGTCTGTA CTCCCTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00536--SAM_1
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	89.92	0.00e+00	902.00
IUUC-Apl-003529	Anas platyrhynchos	75.00	0.00e+00	755.00
IUUC-Aca-004257	Anolis carolinensis	69.82	0.00e+00	696.00
IUUC-Ame-011357	Astyanax mexicanus	51.04	1.00e-113	403.00
IUUC-Bta-013032	Bos taurus	85.74	0.00e+00	862.00
IUUC-Cja-018743	Callithrix jacchus	90.13	0.00e+00	902.00
IUUC-Cfa-021197	Canis familiaris	87.82	0.00e+00	890.00
IUUC-Csa-023954	Chlorocebus sabaeus	90.76	0.00e+00	903.00
IUUC-Cho-025083	Choloepus hoffmanni	72.75	8.00e-157	546.00
IUUC-Cin-025786	Ciona intestinalis	35.14	1.00e-79	290.00
IUUC-Dre-028087	Danio rerio	57.20	1.00e-144	506.00
IUUC-Dno-028919	Dasypus novemcinctus	89.50	0.00e+00	895.00
IUUC-Dor-031112	Dipodomys ordii	88.45	0.00e+00	872.00
IUUC-Ete-032405	Echinops telfairi	87.17	0.00e+00	634.00
IUUC-Eca-033254	Equus caballus	87.61	0.00e+00	876.00
IUUC-Eeu-034545	Erinaceus europaeus	83.40	0.00e+00	811.00
IUUC-Fca-035482	Felis catus	89.29	0.00e+00	896.00
IUUC-Fal-036976	Ficedula albicollis	61.28	2.00e-162	565.00
IUUC-Gmo-039213	Gadus morhua	54.41	4.00e-137	481.00
IUUC-Gga-040561	Gallus gallus	73.38	0.00e+00	735.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.35	7.00e-140	490.00
IUUC-Ggo-045503	Gorilla gorilla	90.97	0.00e+00	907.00
IUUC-Hsa-045910	Homo sapiens	90.76	0.00e+00	906.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	89.92	0.00e+00	705.00
IUUC-Loc-052307	Lepisosteus oculatus	58.53	3.00e-167	581.00
IUUC-Laf-053587	Loxodonta africana	89.08	0.00e+00	895.00
IUUC-Mcc-055679	Macaca mulatta	90.76	0.00e+00	907.00
IUUC-Meu-055962	Macropus eugenii	69.54	0.00e+00	642.00
IUUC-Mga-059652	Meleagris gallopavo	73.38	0.00e+00	741.00
IUUC-Mmr-060943	Microcebus murinus	87.45	0.00e+00	870.00
IUUC-Mdo-062592	Monodelphis domestica	80.38	0.00e+00	809.00
IUUC-Mmu-063577	Mus musculus	82.35	0.00e+00	815.00
IUUC-Mpu-066422	Mustela putorius furo	89.50	0.00e+00	892.00
IUUC-Mlu-067250	Myotis lucifugus	87.82	0.00e+00	876.00
IUUC-Nle-069517	Nomascus leucogenys	90.55	0.00e+00	905.00
IUUC-Opr-070776	Ochotona princeps	88.24	0.00e+00	877.00
IUUC-Ont-071821	Oreochromis niloticus	57.11	8.00e-150	523.00
IUUC-Oan-073706	Ornithorhynchus anatinus	81.89	0.00e+00	827.00
IUUC-Ocu-074766	Oryctolagus cuniculus	80.42	0.00e+00	784.00
IUUC-Ola-086531	Oryzias latipes	56.84	8.00e-147	513.00
IUUC-Oga-088388	Otolemur garnettii	87.39	0.00e+00	877.00
IUUC-Oar-089748	Ovis aries	86.58	0.00e+00	864.00
IUUC-Ptr-090616	Pan troglodytes	90.49	0.00e+00	899.00
IUUC-Pan-091769	Papio anubis	91.57	0.00e+00	660.00
IUUC-Psi-093334	Pelodiscus sinensis	78.15	0.00e+00	735.00
IUUC-Pma-094383	Petromyzon marinus	48.92	4.00e-134	471.00
IUUC-Pfo-096801	Poecilia formosa	55.53	4.00e-145	507.00
IUUC-Pab-098139	Pongo abelii	90.21	0.00e+00	736.00
IUUC-Pca-100523	Procavia capensis	73.53	0.00e+00	716.00
IUUC-Pva-102286	Pteropus vampyrus	87.39	0.00e+00	850.00
IUUC-Rno-104831	Rattus norvegicus	84.45	0.00e+00	835.00
IUUC-Sha-107499	Sarcophilus harrisii	82.35	0.00e+00	833.00
IUUC-Sar-113389	Sorex araneus	83.61	0.00e+00	816.00
IUUC-Tgu-116769	Taeniopygia guttata	72.69	0.00e+00	725.00
IUUC-Tru-118774	Takifugu rubripes	53.70	4.00e-139	488.00
IUUC-Tsy-119595	Tarsius syrichta	78.16	0.00e+00	636.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.14	5.00e-146	510.00
IUUC-Tbe-127938	Tupaia belangeri	80.98	9.00e-145	505.00
IUUC-Ttr-128193	Tursiops truncatus	88.44	0.00e+00	749.00
IUUC-Vpa-130275	Vicugna pacos	89.71	0.00e+00	895.00
IUUC-Xtr-131982	Xenopus tropicalis	61.68	1.00e-171	596.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence