iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036152

Ensembl Protein ID

ENSFCAP00000022006.1

UniProt Accession

M3X5V5; M3X5V5_FELCA

Genbank Protein ID

ENSFCAP00000022006

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02082977

Gene Name

TRIM27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000026440.1	ENSFCAT00000025827.1	ENSFCAP00000022006.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.66	0.00e+00	688.00	IUUC-Hsa-046029
E3 activity/RING/RING	98.40	0.00e+00	689.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

QEQIQNQLDH LKRVKDLKKR RRAQGEQARA ELLSLTQMER EKIVWEFEQL YHSLKEHEYR 60
LLARLEELDL AIYNSINGAI TQFSCNISHL SGLIAQLEEK QQQPTRELLQ DIGDTLSRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTGCCAG GAGCAAATCC AGAACCAGCT GGACCATCTG AAAAGAGTGA AAGACTTAAA 60
GAAGAGGCGT CGGGCACAGG GGGAGCAGGC CCGAGCTGAA CTCTTGGTAA GGGAACTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom

PROSITE

PS50188--B302_SPRY

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	98.40	0.00e+00	697.00
IUUC-Ame-011197	Astyanax mexicanus	51.92	1.00e-53	203.00
IUUC-Bta-013520	Bos taurus	98.66	0.00e+00	690.00
IUUC-Cja-019557	Callithrix jacchus	98.93	0.00e+00	691.00
IUUC-Cfa-020583	Canis familiaris	98.93	0.00e+00	689.00
IUUC-Cpo-021738	Cavia porcellus	96.26	0.00e+00	673.00
IUUC-Csa-023502	Chlorocebus sabaeus	98.66	0.00e+00	689.00
IUUC-Cho-024563	Choloepus hoffmanni	94.57	2.00e-93	335.00
IUUC-Dno-029747	Dasypus novemcinctus	98.13	0.00e+00	686.00
IUUC-Dor-030243	Dipodomys ordii	95.19	0.00e+00	642.00
IUUC-Ete-032749	Echinops telfairi	87.39	7.00e-169	586.00
IUUC-Eca-034246	Equus caballus	98.66	0.00e+00	690.00
IUUC-Eeu-034481	Erinaceus europaeus	94.72	0.00e+00	641.00
IUUC-Ggo-044987	Gorilla gorilla	85.42	5.00e-165	574.00
IUUC-Hsa-046029	Homo sapiens	98.66	0.00e+00	689.00
IUUC-Itr-048438	Ictidomys tridecemlineatus	98.66	0.00e+00	668.00
IUUC-Laf-054488	Loxodonta africana	98.93	0.00e+00	691.00
IUUC-Mcc-055352	Macaca mulatta	98.66	0.00e+00	689.00
IUUC-Mmr-060883	Microcebus murinus	98.40	0.00e+00	687.00
IUUC-Mmu-064242	Mus musculus	98.40	0.00e+00	690.00
IUUC-Mpu-065958	Mustela putorius furo	98.66	0.00e+00	693.00
IUUC-Mlu-068005	Myotis lucifugus	87.67	0.00e+00	634.00
IUUC-Nle-069710	Nomascus leucogenys	98.60	3.00e-96	344.00
IUUC-Opr-071200	Ochotona princeps	98.40	0.00e+00	688.00
IUUC-Ocu-074081	Oryctolagus cuniculus	96.84	1.00e-158	552.00
IUUC-Oga-088784	Otolemur garnettii	98.40	0.00e+00	688.00
IUUC-Oar-089433	Ovis aries	98.66	0.00e+00	690.00
IUUC-Ptr-090595	Pan troglodytes	98.66	0.00e+00	689.00
IUUC-Pan-092027	Papio anubis	98.66	0.00e+00	689.00
IUUC-Pab-098331	Pongo abelii	98.66	0.00e+00	689.00
IUUC-Pca-101091	Procavia capensis	98.93	0.00e+00	692.00
IUUC-Pva-103141	Pteropus vampyrus	98.13	0.00e+00	689.00
IUUC-Rno-105507	Rattus norvegicus	98.40	0.00e+00	690.00
IUUC-Sar-113713	Sorex araneus	94.72	5.00e-179	620.00
IUUC-Ssc-115594	Sus scrofa	98.66	0.00e+00	691.00
IUUC-Tsy-119235	Tarsius syrichta	98.66	0.00e+00	690.00
IUUC-Tbe-127796	Tupaia belangeri	87.50	1.00e-138	486.00
IUUC-Ttr-128738	Tursiops truncatus	98.66	0.00e+00	689.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence