iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005119

UUCD1 version

UUC-AnC-00178

Ensembl Protein ID

ENSACAP00000007541.1

UniProt Accession

G1KGY0; G1KGY0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007679.2	ENSACAT00000007702.2	ENSACAP00000007541.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	9.10e-07	28.8	12	69
E3 activity/RING/RING	2.90e-06	27.6	18	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnl 59
           v e+++CpI   + ++Pv +p + + +  ++I +w++++++ cPv+r+ +t   l P  
   Q: 12   VDEDLICPICSGVLEEPVQAPhCEHAFCNACITQWFSQQQT-CPVDRSVVTVAHLRPVP 69
           56899******************************998887.******99999887764 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC   +++ p+  p C H+f+  C+ +w       s++++CP++r
   Q: 18   CPICSGVLEE-PVQAPhCEHAFCNACITQW------FSQQQTCPVDR 57
           ****999999.777777*************......********987 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGYDVARFQG DVDEDLICPI CSGVLEEPVQ APHCEHAFCN ACITQWFSQQ QTCPVDRSVV 60
TVAHLRPVPR IMRNMLSKLQ ITCDNAVFGC TAVVRLDNLM SHLNDCEHNP KRPVTCEQGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTGGCTGT AGAGAAAGAT GATGACTTAA TCTAAATGGG AAGGAGAGGA ATGAAGATGG 60
ACTATGGTGG CAGACTCTTT CAGAGGAACA ACCCAAGGTC AAAATTGTCC TGCTGTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008974--TRAF-like
IPR015036--USP8_interacting
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR013010--Znf_SIAH

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF08941--USP8_interact

SMART

SM00184--RING

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0031386--F:protein tag
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0030336--P:negative regulation of cell migration
GO:0008285--P:negative regulation of cell proliferation
GO:1901525--P:negative regulation of macromitophagy
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0010498--P:proteasomal protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:2000114--P:regulation of establishment of cell polarity
GO:0045619--P:regulation of lymphocyte differentiation
GO:0043408--P:regulation of MAPK cascade
GO:0045637--P:regulation of myeloid cell differentiation
GO:0051896--P:regulation of protein kinase B signaling

KEGG

acs:100561421

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002398	Ailuropoda melanoleuca	96.53	0.00e+00	644.00
IUUC-Apl-003568	Anas platyrhynchos	98.74	0.00e+00	644.00
IUUC-Ame-010708	Astyanax mexicanus	91.48	6.00e-180	622.00
IUUC-Bta-013428	Bos taurus	90.54	5.00e-174	602.00
IUUC-Cja-019844	Callithrix jacchus	96.54	0.00e+00	640.00
IUUC-Cfa-021124	Canis familiaris	96.85	0.00e+00	645.00
IUUC-Cpo-022325	Cavia porcellus	96.53	0.00e+00	643.00
IUUC-Csa-023113	Chlorocebus sabaeus	96.85	0.00e+00	645.00
IUUC-Cho-024991	Choloepus hoffmanni	97.42	1.00e-112	398.00
IUUC-Cne-026870	Cryptococcus neoformans	38.52	5.00e-20	92.40
IUUC-Dre-028730	Danio rerio	91.17	2.00e-179	620.00
IUUC-Dno-028908	Dasypus novemcinctus	96.52	7.00e-168	582.00
IUUC-Dor-030411	Dipodomys ordii	96.53	0.00e+00	644.00
IUUC-Dme-031868	Drosophila melanogaster	58.10	3.00e-112	397.00
IUUC-Ete-032896	Echinops telfairi	78.87	2.00e-122	431.00
IUUC-Eca-034135	Equus caballus	96.85	0.00e+00	645.00
IUUC-Eeu-034675	Erinaceus europaeus	96.53	0.00e+00	643.00
IUUC-Fca-035612	Felis catus	96.85	0.00e+00	645.00
IUUC-Fal-036922	Ficedula albicollis	98.77	1.00e-42	163.00
IUUC-Gmo-039648	Gadus morhua	88.01	2.00e-173	600.00
IUUC-Gga-040474	Gallus gallus	99.68	0.00e+00	659.00
IUUC-Gac-041951	Gasterosteus aculeatus	89.27	5.00e-176	609.00
IUUC-Ggo-045126	Gorilla gorilla	96.54	0.00e+00	640.00
IUUC-Hsa-046402	Homo sapiens	96.85	0.00e+00	645.00
IUUC-Itr-047895	Ictidomys tridecemlineatus	96.85	0.00e+00	645.00
IUUC-Lch-050266	Latimeria chalumnae	93.69	0.00e+00	632.00
IUUC-Loc-052547	Lepisosteus oculatus	92.43	0.00e+00	625.00
IUUC-Lma-053014	Leptosphaeria maculans	34.68	2.00e-12	66.60
IUUC-Laf-054332	Loxodonta africana	96.23	0.00e+00	639.00
IUUC-Mcc-055869	Macaca mulatta	96.85	0.00e+00	645.00
IUUC-Meu-056735	Macropus eugenii	96.86	4.00e-168	583.00
IUUC-Mga-060100	Meleagris gallopavo	99.68	0.00e+00	659.00
IUUC-Mmr-061382	Microcebus murinus	96.85	0.00e+00	645.00
IUUC-Mdo-062581	Monodelphis domestica	33.88	6.00e-23	103.00
IUUC-Mmu-064225	Mus musculus	96.53	0.00e+00	644.00
IUUC-Mpu-066709	Mustela putorius furo	96.85	0.00e+00	645.00
IUUC-Mlu-067168	Myotis lucifugus	95.90	0.00e+00	642.00
IUUC-Nle-070176	Nomascus leucogenys	96.85	0.00e+00	645.00
IUUC-Opr-070259	Ochotona princeps	96.53	0.00e+00	643.00
IUUC-Ont-071235	Oreochromis niloticus	90.54	3.00e-178	617.00
IUUC-Oan-072850	Ornithorhynchus anatinus	93.42	1.00e-81	295.00
IUUC-Ocu-074165	Oryctolagus cuniculus	96.53	0.00e+00	643.00
IUUC-Ola-086658	Oryzias latipes	88.96	1.00e-174	604.00
IUUC-Oga-088933	Otolemur garnettii	96.85	0.00e+00	645.00
IUUC-Oar-090089	Ovis aries	96.53	0.00e+00	644.00
IUUC-Ptr-091263	Pan troglodytes	96.85	0.00e+00	645.00
IUUC-Pan-092926	Papio anubis	96.85	0.00e+00	645.00
IUUC-Psi-093934	Pelodiscus sinensis	91.82	8.00e-172	595.00
IUUC-Pma-094578	Petromyzon marinus	68.03	6.00e-126	443.00
IUUC-Pno-094854	Phaeosphaeria nodorum	36.59	2.00e-13	70.10
IUUC-Pfo-097431	Poecilia formosa	90.54	5.00e-178	616.00
IUUC-Pab-097852	Pongo abelii	96.85	0.00e+00	645.00
IUUC-Pca-100496	Procavia capensis	88.68	5.00e-165	573.00
IUUC-Pva-103157	Pteropus vampyrus	97.00	5.00e-115	405.00
IUUC-Pgr-103416	Puccinia graminis	30.77	3.00e-13	69.70
IUUC-Pyt-104429	Pyrenophora triticirepentis	37.61	2.00e-12	66.60
IUUC-Rno-105928	Rattus norvegicus	96.53	0.00e+00	643.00
IUUC-Sha-107556	Sarcophilus harrisii	96.86	0.00e+00	642.00
IUUC-Sar-113208	Sorex araneus	96.85	0.00e+00	645.00
IUUC-Ssc-116011	Sus scrofa	96.53	0.00e+00	644.00
IUUC-Tgu-116882	Taeniopygia guttata	75.00	2.00e-73	268.00
IUUC-Tru-117987	Takifugu rubripes	90.22	2.00e-177	614.00
IUUC-Tsy-118785	Tarsius syrichta	96.53	0.00e+00	638.00
IUUC-Tni-120165	Tetraodon nigroviridis	89.91	5.00e-177	613.00
IUUC-Tbe-127920	Tupaia belangeri	97.50	5.00e-117	412.00
IUUC-Ttr-129160	Tursiops truncatus	96.21	0.00e+00	642.00
IUUC-Vpa-130629	Vicugna pacos	96.85	0.00e+00	645.00
IUUC-Xtr-131895	Xenopus tropicalis	95.58	0.00e+00	639.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence