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Tag Content
UUCD2 ID IUUC-Cpo-021898
UUCD1 version UUC-CaP-00805
Ensembl Protein ID ENSCPOP00000016261.1
UniProt Accession H0VZX7; H0VZX7_CAVPO
Genbank Protein ID ENSCPOP00000016261
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02007099
Gene Name FBXW8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000005448.3 ENSCPOT00000022261.1 ENSCPOP00000016261.1
ENSCPOG00000005448.3 ENSCPOT00000005506.2 ENSCPOP00000004904.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.10e-12 46.8 472 501
E3 adaptor/Cullin RING/SCF/F-box 1.20e-06 28.7 102 157
UBD/Beta-Prp 2.00e-40 138.8 204 504
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlr 31
           H+ +v++++ +d+ +vsG+  g + vWD+r
   Q: 472  HQLGVSAVQMDDWKIVSGGEEGLVSVWDYR 501
           7778999999669***************86 PP
   

   E3 adaptor/Cullin RING/SCF/F-box
   S: 91   tptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           t   e +       +lp+e+ ++i+++ld+++l+r+a+v+++w+ +a+++ lw ++
   Q: 102  TTQNEMDDVPFFDVQLPYELAINIFQYLDRKDLGRCAQVSKTWKVIAEDEVLWYRL 157
           333344445667789*****************************999999999765 PP
   

   UBD/Beta-Prp
   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae.........vtavkfspdgkilvtgseDrtikvwdlstgk 85
           ++ +++v+++v+    + ++++g+++g ++vwd++t+++++ + + e e         v+ v+++++  + v + eD++++vwdl+tgk
   Q: 204  EHIPEAVLCDVHS--YDGVVIAGYTSGDVRVWDTRTWDYVAPFLETEYEedepgmqpyVSFVRINSS--LAVAAYEDGFLHVWDLRTGK 288
           5566778887777..999*********************5555555555555679999*********..9******************* PP
   S: 86   cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllr 173
             ++  +h++++ +l++s++g +++++s+ +++++   e+g++  + + + +++v ++++ pd+ ++ v+ ++ + + ++ lk ++  r
   Q: 289  RPVHRFEHDARIQALALSREGATVATASAFDVVMLSPNEEGYWQIAAEFEVQKLVDYLEIVPDTgRYPVAIATAGDL-VYLLKAEDSAR 376
           9999999*********************************************************************9.5********** PP
   S: 174  tltgghtdsvyslsfdsng.....kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdlrsgdl 256
           tl     ++++sl+++ n+     k+l ++ + +++ +++l++++c+ +l +    ++++++  +   ++vsg++D+ +ri+dlr++++
   Q: 377  TLHYVYGQPITSLDVSANQvafgvKSLGWVYEGNKILVYSLEAERCLSKLGNALGDFTCINLRdSPPSLMVSGNMDRRVRIHDLRTDKI 465
           **999*********************************************************96788999******************* PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkne 298
             +l+ h+  v++v++   +d+++v+g+e++ v +w++++++
   Q: 466  ALSLSAHQLGVSAVQM---DDWKIVSGGEEGLVSVWDYRMSQ 504
           ********99999999...*******************9876 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
MDEHSLEEFR RHWQEELAQA QALRKLRRQR RAEEAVGRGE QASGYLALAQ GLPVRPESCE 60
LLPTPPPALE RPNKSTPMHS IVPPLEPEAS DQLPLIPQLV TTTQNEMDDV PFFDVQLPYE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021898|E3,WD_repeat;E3,F-box;UBD,Beta-Prp|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACGAGC ACAGCCTGGA GGAGTTCCGT CGGCACTGGC AGGAGGAGCT GGCCCAGGCC 60
CAGGCGCTGA GGAAACTGCG GCGGCAGCGA AGGGCCGAGG AGGCGGTCGG GCGCGGCGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021898|E3,WD_repeat;E3,F-box;UBD,Beta-Prp|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12937--F-box-like
SMART

SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0060716--P:labyrinthine layer blood vessel development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0060712--P:spongiotrophoblast layer development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001274 Ailuropoda melanoleuca 90.00 0.00e+00 960.00
IUUC-Apl-003239 Anas platyrhynchos 62.13 0.00e+00 701.00
IUUC-Aca-004756 Anolis carolinensis 61.33 4.00e-140 490.00
IUUC-Ame-011198 Astyanax mexicanus 41.06 6.00e-55 207.00
IUUC-Bta-012430 Bos taurus 55.41 3.00e-147 514.00
IUUC-Cja-019131 Callithrix jacchus 74.63 0.00e+00 870.00
IUUC-Cfa-021022 Canis familiaris 81.95 0.00e+00 973.00
IUUC-Csa-023452 Chlorocebus sabaeus 77.98 0.00e+00 910.00
IUUC-Cho-024759 Choloepus hoffmanni 72.31 0.00e+00 825.00
IUUC-Dre-028123 Danio rerio 43.86 4.00e-146 511.00
IUUC-Dno-029045 Dasypus novemcinctus 91.90 0.00e+00 888.00
IUUC-Dor-030433 Dipodomys ordii 89.49 0.00e+00 773.00
IUUC-Ete-032465 Echinops telfairi 89.68 0.00e+00 778.00
IUUC-Eca-034134 Equus caballus 92.28 0.00e+00 964.00
IUUC-Eeu-035047 Erinaceus europaeus 80.82 0.00e+00 823.00
IUUC-Fca-036574 Felis catus 90.65 0.00e+00 941.00
IUUC-Fal-037665 Ficedula albicollis 61.82 7.00e-180 623.00
IUUC-Gmo-039137 Gadus morhua 36.15 1.00e-62 233.00
IUUC-Gga-040711 Gallus gallus 59.04 0.00e+00 676.00
IUUC-Gac-041675 Gasterosteus aculeatus 54.21 1.00e-56 212.00
IUUC-Ggo-045331 Gorilla gorilla 85.40 0.00e+00 883.00
IUUC-Hsa-046240 Homo sapiens 77.11 0.00e+00 915.00
IUUC-Itr-048412 Ictidomys tridecemlineatus 93.09 0.00e+00 943.00
IUUC-Loc-052631 Lepisosteus oculatus 54.27 6.00e-167 581.00
IUUC-Laf-054127 Loxodonta africana 81.12 4.00e-63 233.00
IUUC-Mcc-055083 Macaca mulatta 77.45 0.00e+00 911.00
IUUC-Mga-060113 Meleagris gallopavo 63.71 0.00e+00 677.00
IUUC-Mmr-061780 Microcebus murinus 89.64 0.00e+00 947.00
IUUC-Mdo-063066 Monodelphis domestica 63.03 0.00e+00 731.00
IUUC-Mmu-063524 Mus musculus 77.65 0.00e+00 881.00
IUUC-Mpu-066913 Mustela putorius furo 90.76 0.00e+00 946.00
IUUC-Mlu-067924 Myotis lucifugus 81.36 0.00e+00 940.00
IUUC-Nle-069558 Nomascus leucogenys 76.99 0.00e+00 860.00
IUUC-Opr-070506 Ochotona princeps 87.11 0.00e+00 934.00
IUUC-Ont-071514 Oreochromis niloticus 48.23 5.00e-143 501.00
IUUC-Ocu-074477 Oryctolagus cuniculus 90.52 0.00e+00 929.00
IUUC-Ola-087416 Oryzias latipes 43.66 2.00e-144 506.00
IUUC-Oga-088643 Otolemur garnettii 90.04 0.00e+00 955.00
IUUC-Oar-090172 Ovis aries 89.22 0.00e+00 943.00
IUUC-Ptr-090870 Pan troglodytes 76.95 0.00e+00 918.00
IUUC-Pan-092017 Papio anubis 76.90 0.00e+00 901.00
IUUC-Psi-093794 Pelodiscus sinensis 65.46 0.00e+00 691.00
IUUC-Pfo-096192 Poecilia formosa 49.80 2.00e-146 512.00
IUUC-Pab-097882 Pongo abelii 76.29 0.00e+00 910.00
IUUC-Pca-100902 Procavia capensis 75.07 1.00e-141 496.00
IUUC-Pva-103139 Pteropus vampyrus 82.92 0.00e+00 989.00
IUUC-Rno-105798 Rattus norvegicus 83.86 0.00e+00 891.00
IUUC-Sha-106576 Sarcophilus harrisii 67.42 0.00e+00 709.00
IUUC-Ssc-115923 Sus scrofa 73.64 0.00e+00 885.00
IUUC-Tgu-116667 Taeniopygia guttata 57.07 2.00e-120 425.00
IUUC-Tru-118323 Takifugu rubripes 43.56 8.00e-139 487.00
IUUC-Tsy-118818 Tarsius syrichta 77.17 2.00e-111 395.00
IUUC-Tni-120438 Tetraodon nigroviridis 41.88 4.00e-133 468.00
IUUC-Tbe-127784 Tupaia belangeri 93.20 3.00e-113 401.00
IUUC-Ttr-128288 Tursiops truncatus 72.38 0.00e+00 827.00
IUUC-Vpa-130307 Vicugna pacos 85.90 0.00e+00 808.00
Created Date 25-Jun-2017

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