iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025215

UUCD1 version

UUC-CiI-00010

Ensembl Protein ID

ENSCINP00000010583.3

UniProt Accession

F6VAW2; F6VAW2_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000005141.3	ENSCINT00000010583.3	ENSCINP00000010583.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.80e-09	35.6	351	388
UBD/Alpha-Helix/CUE	8.70e-08	31.9	462	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+e +++  + lpCgH+fh  Cl  w        +  +CP+C
   Q: 351  CAICWEQMET-ARKLPCGHFFHSPCLRSW------LEQDTTCPTC 388
           ********99.******************......********** PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+t++ ++++iFP+ +  vi+ +L ++tgs+e++++ +Leg+
   Q: 462  QLDTMVREVQDIFPQIPAQVIRNDL-QLTGSVETTTDHILEGQ 503
           689**********************.***************96 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MPAIIIFRRF PMPSISVYST ASFILLSLSI LWAHTTILEA CNLPTDKDVN VWTYPTQDPN 60
ASQPPTSSVT LSVNVFTLML DEPVCLVLAV NATYCLLAII VQIIQKLVFG KLRAIERQHM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGGCTA TTATTATATT TCGGAGGTTT CCAATGCCCA GTATATCTGT ATACTCCACT 60
GCCAGTTTCA TACTGTTAAG TCTCTCAATT TTATGGGCTC ATACAACTAT ACTGGAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	26.14	2.00e-25	108.00
IUUC-Aml-001300	Ailuropoda melanoleuca	48.41	3.00e-150	523.00
IUUC-Atr-002892	Amborella trichopoda	28.10	2.00e-34	139.00
IUUC-Apl-003404	Anas platyrhynchos	49.62	6.00e-147	513.00
IUUC-Aca-004559	Anolis carolinensis	49.22	7.00e-145	505.00
IUUC-Aly-006352	Arabidopsis lyrata	29.75	2.00e-33	135.00
IUUC-Ath-006702	Arabidopsis thaliana	27.97	2.00e-33	135.00
IUUC-Ago-007894	Ashbya gossypii	23.50	2.00e-13	69.30
IUUC-Acl-008041	Aspergillus clavatus	22.34	1.00e-17	84.00
IUUC-Afl-008427	Aspergillus flavus	23.35	1.00e-17	84.00
IUUC-Afu-009023	Aspergillus fumigatus	22.07	5.00e-18	85.10
IUUC-Ani-009133	Aspergillus nidulans	22.30	2.00e-19	89.70
IUUC-Ang-009612	Aspergillus niger	24.32	8.00e-20	90.90
IUUC-Aor-010045	Aspergillus oryzae	23.43	1.00e-18	87.40
IUUC-Ate-010533	Aspergillus terreus	22.30	5.00e-18	84.70
IUUC-Ame-011640	Astyanax mexicanus	44.88	2.00e-151	528.00
IUUC-Bgr-012122	Blumeria graminis	23.76	4.00e-14	72.00
IUUC-Bta-012980	Bos taurus	47.38	8.00e-156	542.00
IUUC-Bci-013675	Botrytis cinerea	36.46	8.00e-13	67.80
IUUC-Bdi-015070	Brachypodium distachyon	29.32	2.00e-36	145.00
IUUC-Bol-015674	Brassica oleracea	30.38	5.00e-33	134.00
IUUC-Bra-017662	Brassica rapa	26.37	2.00e-25	108.00
IUUC-Cel-018598	Caenorhabditis elegans	25.74	3.00e-36	145.00
IUUC-Cja-019577	Callithrix jacchus	44.12	3.00e-154	537.00
IUUC-Cfa-020793	Canis familiaris	48.28	7.00e-149	519.00
IUUC-Cpo-022387	Cavia porcellus	45.09	7.00e-156	542.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	24.68	8.00e-25	106.00
IUUC-Csa-023168	Chlorocebus sabaeus	44.77	9.00e-157	545.00
IUUC-Cho-024433	Choloepus hoffmanni	47.59	3.00e-115	407.00
IUUC-Csv-026133	Ciona savignyi	68.27	0.00e+00	759.00
IUUC-Cne-027002	Cryptococcus neoformans	27.16	2.00e-28	119.00
IUUC-Cme-027285	Cyanidioschyzon merolae	27.92	9.00e-21	93.60
IUUC-Dre-027594	Danio rerio	43.75	3.00e-139	487.00
IUUC-Dno-029407	Dasypus novemcinctus	48.30	1.00e-146	511.00
IUUC-Dor-030961	Dipodomys ordii	49.15	2.00e-148	517.00
IUUC-Dse-031498	Dothistroma septosporum	26.16	1.00e-12	67.40
IUUC-Dme-031969	Drosophila melanogaster	25.17	2.00e-26	112.00
IUUC-Ete-032962	Echinops telfairi	41.86	1.00e-117	415.00
IUUC-Eca-033683	Equus caballus	43.55	6.00e-142	496.00
IUUC-Eeu-034515	Erinaceus europaeus	54.74	3.00e-40	157.00
IUUC-Fca-035398	Felis catus	48.94	2.00e-147	514.00
IUUC-Fal-036758	Ficedula albicollis	43.98	7.00e-136	476.00
IUUC-Fox-037902	Fusarium oxysporum	23.40	4.00e-18	85.50
IUUC-Fso-038418	Fusarium solani	32.89	3.00e-14	72.80
IUUC-Gmo-039014	Gadus morhua	44.35	8.00e-142	496.00
IUUC-Ggr-040076	Gaeumannomyces graminis	23.56	4.00e-17	82.00
IUUC-Gga-040575	Gallus gallus	47.81	1.00e-150	525.00
IUUC-Gac-041414	Gasterosteus aculeatus	43.59	4.00e-141	493.00
IUUC-Gma-044123	Glycine max	29.08	9.00e-34	136.00
IUUC-Ggo-044858	Gorilla gorilla	27.52	2.00e-30	125.00
IUUC-Hsa-046272	Homo sapiens	44.77	1.00e-154	538.00
IUUC-Hvu-047279	Hordeum vulgare	28.34	2.00e-34	138.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	48.33	5.00e-151	526.00
IUUC-Kpa-049117	Komagataella pastoris	21.60	4.00e-09	55.10
IUUC-Lch-050491	Latimeria chalumnae	46.70	1.00e-147	515.00
IUUC-Lpe-051229	Leersia perrieri	39.44	9.00e-13	66.60
IUUC-Loc-052758	Lepisosteus oculatus	43.66	4.00e-148	516.00
IUUC-Lma-052997	Leptosphaeria maculans	23.41	3.00e-19	89.00
IUUC-Laf-053452	Loxodonta africana	48.95	2.00e-150	524.00
IUUC-Mcc-055820	Macaca mulatta	48.95	1.00e-150	525.00
IUUC-Meu-056726	Macropus eugenii	43.79	3.00e-119	421.00
IUUC-Mor-057082	Magnaporthe oryzae	23.44	6.00e-15	75.10
IUUC-Mpo-057573	Magnaporthe poae	24.21	2.00e-17	82.40
IUUC-Mtr-058601	Medicago truncatula	27.78	1.00e-36	145.00
IUUC-Mla-059168	Melampsora laricipopulina	27.54	4.00e-30	125.00
IUUC-Mga-059937	Meleagris gallopavo	49.07	9.00e-150	522.00
IUUC-Mvi-060515	Microbotryum violaceum	23.48	4.00e-19	89.00
IUUC-Mmr-060730	Microcebus murinus	45.41	5.00e-153	533.00
IUUC-Mdo-062771	Monodelphis domestica	47.99	6.00e-153	533.00
IUUC-Mmu-064219	Mus musculus	45.43	3.00e-155	540.00
IUUC-Mac-064789	Musa acuminata	29.11	9.00e-39	153.00
IUUC-Mpu-066796	Mustela putorius furo	48.47	2.00e-148	517.00
IUUC-Mlu-068189	Myotis lucifugus	47.89	2.00e-146	510.00
IUUC-Nfi-068389	Neosartorya fischeri	21.79	2.00e-17	82.80
IUUC-Ncr-068742	Neurospora crassa	22.96	2.00e-14	72.80
IUUC-Nle-069239	Nomascus leucogenys	46.99	1.00e-154	538.00
IUUC-Opr-070702	Ochotona princeps	50.78	4.00e-57	214.00
IUUC-Ont-072033	Oreochromis niloticus	44.22	1.00e-148	518.00
IUUC-Oan-073717	Ornithorhynchus anatinus	52.78	5.00e-141	493.00
IUUC-Ocu-074145	Oryctolagus cuniculus	44.41	9.00e-155	538.00
IUUC-Oba-075221	Oryza barthii	27.76	1.00e-36	146.00
IUUC-Obr-076914	Oryza brachyantha	28.36	3.00e-37	148.00
IUUC-Ogu-078124	Oryza glumaepatula	27.76	1.00e-36	146.00
IUUC-Oin-080013	Oryza indica	27.84	1.00e-36	145.00
IUUC-Olo-080247	Oryza longistaminata	27.54	6.00e-33	133.00
IUUC-Ome-081769	Oryza meridionalis	28.45	5.00e-38	150.00
IUUC-Oni-082946	Oryza nivara	27.76	1.00e-36	146.00
IUUC-Opu-083268	Oryza punctata	26.90	2.00e-23	102.00
IUUC-Oru-085114	Oryza rufipogon	27.76	1.00e-36	146.00
IUUC-Osa-085829	Oryza sativa	28.99	2.00e-36	145.00
IUUC-Ola-087152	Oryzias latipes	44.06	5.00e-144	503.00
IUUC-Olu-087894	Ostreococcus lucimarinus	24.76	2.00e-22	98.60
IUUC-Oga-088486	Otolemur garnettii	49.06	6.00e-152	529.00
IUUC-Oar-089310	Ovis aries	49.06	7.00e-154	535.00
IUUC-Ptr-090649	Pan troglodytes	48.68	3.00e-152	530.00
IUUC-Pan-091692	Papio anubis	42.51	1.00e-143	501.00
IUUC-Psi-093064	Pelodiscus sinensis	54.55	5.00e-134	469.00
IUUC-Pma-094763	Petromyzon marinus	51.19	5.00e-71	259.00
IUUC-Pno-094883	Phaeosphaeria nodorum	22.02	2.00e-17	83.20
IUUC-Ppa-095969	Physcomitrella patens	29.19	9.00e-40	156.00
IUUC-Pfo-096810	Poecilia formosa	44.43	2.00e-146	511.00
IUUC-Pab-097859	Pongo abelii	48.95	7.00e-151	525.00
IUUC-Pop-099245	Populus trichocarpa	26.28	7.00e-36	144.00
IUUC-Pca-100344	Procavia capensis	44.23	3.00e-147	513.00
IUUC-Ppe-101829	Prunus persica	28.14	4.00e-40	157.00
IUUC-Pva-103114	Pteropus vampyrus	31.30	3.00e-78	284.00
IUUC-Pgr-103286	Puccinia graminis	25.51	2.00e-24	106.00
IUUC-Ptt-103919	Puccinia triticina	24.73	7.00e-22	97.10
IUUC-Pte-104372	Pyrenophora teres	22.68	1.00e-19	90.50
IUUC-Pyt-104456	Pyrenophora triticirepentis	22.28	7.00e-18	84.70
IUUC-Rno-105880	Rattus norvegicus	46.35	1.00e-147	515.00
IUUC-Sha-107015	Sarcophilus harrisii	47.68	8.00e-148	515.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	24.14	6.00e-24	104.00
IUUC-Spo-108308	Schizosaccharomyces pombe	23.86	2.00e-26	113.00
IUUC-Ssl-108558	Sclerotinia sclerotiorum	36.46	8.00e-13	67.80
IUUC-Smo-109664	Selaginella moellendorffii	27.40	2.00e-35	142.00
IUUC-Sit-110276	Setaria italica	28.99	4.00e-36	144.00
IUUC-Sly-111819	Solanum lycopersicum	27.33	5.00e-34	137.00
IUUC-Stu-112048	Solanum tuberosum	27.54	7.00e-36	144.00
IUUC-Sar-113397	Sorex araneus	53.83	3.00e-120	424.00
IUUC-Sbi-114027	Sorghum bicolor	29.55	1.00e-41	162.00
IUUC-Sre-115212	Sporisorium reilianum	24.44	3.00e-21	95.90
IUUC-Ssc-115988	Sus scrofa	40.94	6.00e-48	182.00
IUUC-Tgu-116717	Taeniopygia guttata	46.32	1.00e-147	515.00
IUUC-Tru-117805	Takifugu rubripes	43.97	2.00e-146	511.00
IUUC-Tsy-119442	Tarsius syrichta	43.98	2.00e-127	447.00
IUUC-Tni-119777	Tetraodon nigroviridis	47.62	6.00e-104	369.00
IUUC-Tca-121462	Theobroma cacao	27.88	5.00e-37	147.00
IUUC-Tre-122204	Trichoderma reesei	32.32	5.00e-15	75.10
IUUC-Tvi-122550	Trichoderma virens	33.57	1.00e-14	74.30
IUUC-Tae-124673	Triticum aestivum	28.66	3.00e-35	141.00
IUUC-Tur-126538	Triticum urartu	26.47	3.00e-25	108.00
IUUC-Tme-127197	Tuber melanosporum	25.16	4.00e-21	95.50
IUUC-Tbe-127322	Tupaia belangeri	35.22	5.00e-47	181.00
IUUC-Ttr-128181	Tursiops truncatus	48.87	4.00e-152	530.00
IUUC-Uma-129401	Ustilago maydis	25.87	3.00e-15	75.90
IUUC-Vda-129968	Verticillium dahliae	32.17	2.00e-13	69.70
IUUC-Vpa-130483	Vicugna pacos	44.84	1.00e-99	355.00
IUUC-Vvi-130944	Vitis vinifera	27.84	6.00e-37	147.00
IUUC-Xtr-132614	Xenopus tropicalis	46.07	3.00e-132	464.00
IUUC-Xma-133943	Xiphophorus maculatus	44.59	2.00e-146	511.00
IUUC-Yli-134552	Yarrowia lipolytica	24.14	1.00e-13	69.30
IUUC-Zma-135530	Zea mays	29.11	4.00e-38	151.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence