iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028395

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 22

Genbank Nucleotide ID

CU302301

Gene Name

klhl22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000088807.4	ENSDART00000129372.2	ENSDARP00000106872.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.70e-18	67.7	49	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+l v+g+ ++ah+i Laas+++F+ +f ++l+e++ + ++ +++v+++++  ll+F+Yt++l++
   Q: 49   DVVLLVEGKPIQAHRILLAASCDYFRGMFAGGLREMQ-QTEIPVHGVSYTAMMKLLDFIYTSELEL 113
           9***********************************9.*************************976 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MADDLVSCTA GGAVRSAQPC AKQKYRSTAH SQGLLDGLLM LRQGGILFDV VLLVEGKPIQ 60
AHRILLAASC DYFRGMFAGG LREMQQTEIP VHGVSYTAMM KLLDFIYTSE LELDLDTVQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGGAGAAA CTCAACTGGC GTTCAAAAAT CAAAACATCC CGAAACGTCC TCGTCGTTTT 60
CATATTAATA TTCATCATTA TCATCGAGTG ACTGCAGTCA TTAAACAGCT TGTTTTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

KEGG

dre:100333714

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	59.42	0.00e+00	755.00
IUUC-Apl-004081	Anas platyrhynchos	60.77	0.00e+00	786.00
IUUC-Aca-005015	Anolis carolinensis	53.67	0.00e+00	691.00
IUUC-Ame-011712	Astyanax mexicanus	79.59	0.00e+00	1044.00
IUUC-Bta-012594	Bos taurus	59.93	0.00e+00	762.00
IUUC-Bol-016582	Brassica oleracea	30.60	3.00e-12	67.40
IUUC-Bra-017771	Brassica rapa	31.15	8.00e-13	69.70
IUUC-Cja-019752	Callithrix jacchus	58.10	2.00e-177	615.00
IUUC-Cfa-020884	Canis familiaris	59.90	0.00e+00	767.00
IUUC-Cpo-021711	Cavia porcellus	60.75	0.00e+00	777.00
IUUC-Csa-023211	Chlorocebus sabaeus	60.06	0.00e+00	768.00
IUUC-Dno-030096	Dasypus novemcinctus	58.22	0.00e+00	754.00
IUUC-Dor-030709	Dipodomys ordii	60.00	3.00e-121	429.00
IUUC-Eca-033388	Equus caballus	59.74	0.00e+00	766.00
IUUC-Eeu-034616	Erinaceus europaeus	53.23	0.00e+00	669.00
IUUC-Fca-035815	Felis catus	60.06	0.00e+00	767.00
IUUC-Fal-037311	Ficedula albicollis	61.66	0.00e+00	765.00
IUUC-Gmo-039571	Gadus morhua	63.70	0.00e+00	699.00
IUUC-Gga-040992	Gallus gallus	60.61	0.00e+00	785.00
IUUC-Gac-042041	Gasterosteus aculeatus	67.09	0.00e+00	895.00
IUUC-Ggo-045141	Gorilla gorilla	56.36	0.00e+00	715.00
IUUC-Hsa-045984	Homo sapiens	60.06	0.00e+00	769.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	60.59	0.00e+00	775.00
IUUC-Lch-049700	Latimeria chalumnae	54.95	0.00e+00	667.00
IUUC-Loc-052141	Lepisosteus oculatus	68.56	0.00e+00	903.00
IUUC-Laf-053487	Loxodonta africana	60.03	0.00e+00	762.00
IUUC-Mcc-054682	Macaca mulatta	61.65	0.00e+00	644.00
IUUC-Meu-055937	Macropus eugenii	53.62	0.00e+00	677.00
IUUC-Mga-059953	Meleagris gallopavo	60.61	0.00e+00	785.00
IUUC-Mmr-061743	Microcebus murinus	60.29	0.00e+00	772.00
IUUC-Mdo-062328	Monodelphis domestica	59.42	0.00e+00	757.00
IUUC-Mmu-063979	Mus musculus	62.11	0.00e+00	765.00
IUUC-Mpu-066750	Mustela putorius furo	60.23	0.00e+00	770.00
IUUC-Mlu-066960	Myotis lucifugus	60.03	0.00e+00	766.00
IUUC-Nle-069690	Nomascus leucogenys	58.96	0.00e+00	686.00
IUUC-Opr-071059	Ochotona princeps	56.91	0.00e+00	709.00
IUUC-Ont-072004	Oreochromis niloticus	70.63	0.00e+00	862.00
IUUC-Oan-073172	Ornithorhynchus anatinus	53.07	4.00e-176	611.00
IUUC-Ogu-078976	Oryza glumaepatula	30.60	6.00e-14	73.20
IUUC-Ome-081730	Oryza meridionalis	30.60	5.00e-14	73.60
IUUC-Oru-084212	Oryza rufipogon	30.60	6.00e-14	73.20
IUUC-Ola-086599	Oryzias latipes	68.32	0.00e+00	925.00
IUUC-Oga-087980	Otolemur garnettii	59.61	0.00e+00	769.00
IUUC-Oar-089956	Ovis aries	51.90	7.00e-162	563.00
IUUC-Ptr-090598	Pan troglodytes	59.11	0.00e+00	690.00
IUUC-Pan-092387	Papio anubis	61.45	0.00e+00	644.00
IUUC-Psi-093484	Pelodiscus sinensis	59.55	0.00e+00	773.00
IUUC-Pma-094224	Petromyzon marinus	47.02	4.00e-162	564.00
IUUC-Ppa-095902	Physcomitrella patens	34.08	5.00e-16	79.30
IUUC-Pfo-096149	Poecilia formosa	68.08	0.00e+00	912.00
IUUC-Pab-098097	Pongo abelii	60.06	0.00e+00	769.00
IUUC-Pca-100118	Procavia capensis	60.86	4.00e-123	435.00
IUUC-Pva-103174	Pteropus vampyrus	58.94	1.00e-91	330.00
IUUC-Rno-105350	Rattus norvegicus	59.93	0.00e+00	764.00
IUUC-Sha-106817	Sarcophilus harrisii	58.43	4.00e-90	325.00
IUUC-Sar-113490	Sorex araneus	59.88	2.00e-117	416.00
IUUC-Ssc-115827	Sus scrofa	60.10	0.00e+00	760.00
IUUC-Tgu-116748	Taeniopygia guttata	63.50	0.00e+00	715.00
IUUC-Tru-118644	Takifugu rubripes	66.13	0.00e+00	904.00
IUUC-Tsy-118888	Tarsius syrichta	54.92	4.00e-178	618.00
IUUC-Tni-120060	Tetraodon nigroviridis	62.23	0.00e+00	731.00
IUUC-Ttr-129183	Tursiops truncatus	59.03	0.00e+00	685.00
IUUC-Xtr-132780	Xenopus tropicalis	57.72	0.00e+00	751.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence