iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089956

Ensembl Protein ID

ENSOARP00000018349.1

UniProt Accession

W5Q6K8; W5Q6K8_SHEEP

Genbank Protein ID

ENSOARP00000018349

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01040341

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000017096.1	ENSOART00000018611.1	ENSOARP00000018349.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.10e-19	69.8	51	115

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++ +ah+i Laas+++F+ +f ++l+e++ +++v i++v+++++r++l+F+Yt +l++
   Q: 51   DVVLVVEGKQLEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYSAMRQILHFIYTAELEL 115
           9***********************************8.************************9976 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAEEQELARL CKLPTQPSHP HCVSNTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGKQ 60
LEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYSA MRQILHFIYT AELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTGCC AGCTGACAGC CGCGGAGCTG AGGTCGGGAG CGGTGGTCAG GATGGCGGAA 60
GAGCAGGAGC TCGCCCGGCT CTGCAAGTTG CCCACGCAGC CCTCCCACCC ACACTGCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011498--Kelch_2
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF07646--Kelch_2

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	78.61	0.00e+00	884.00
IUUC-Apl-004081	Anas platyrhynchos	64.25	0.00e+00	736.00
IUUC-Aca-005015	Anolis carolinensis	57.33	0.00e+00	632.00
IUUC-Ame-011712	Astyanax mexicanus	50.25	1.00e-150	526.00
IUUC-Bta-012594	Bos taurus	82.66	0.00e+00	957.00
IUUC-Cja-019752	Callithrix jacchus	80.27	0.00e+00	707.00
IUUC-Cfa-020884	Canis familiaris	79.09	0.00e+00	923.00
IUUC-Cpo-021711	Cavia porcellus	77.63	0.00e+00	910.00
IUUC-Csa-023211	Chlorocebus sabaeus	78.93	0.00e+00	918.00
IUUC-Dre-028395	Danio rerio	51.88	3.00e-157	548.00
IUUC-Dno-030096	Dasypus novemcinctus	75.97	0.00e+00	887.00
IUUC-Dor-030709	Dipodomys ordii	83.38	5.00e-171	594.00
IUUC-Eca-033388	Equus caballus	79.25	0.00e+00	924.00
IUUC-Eeu-034616	Erinaceus europaeus	76.89	0.00e+00	682.00
IUUC-Fca-035815	Felis catus	78.93	0.00e+00	920.00
IUUC-Fal-037311	Ficedula albicollis	66.10	0.00e+00	718.00
IUUC-Gmo-039571	Gadus morhua	46.30	6.00e-122	431.00
IUUC-Gga-040992	Gallus gallus	64.25	0.00e+00	737.00
IUUC-Gac-042041	Gasterosteus aculeatus	48.15	2.00e-141	495.00
IUUC-Ggo-045141	Gorilla gorilla	73.10	0.00e+00	840.00
IUUC-Hsa-045984	Homo sapiens	79.09	0.00e+00	921.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	78.93	0.00e+00	922.00
IUUC-Lch-049700	Latimeria chalumnae	58.22	2.00e-179	622.00
IUUC-Loc-052141	Lepisosteus oculatus	53.63	6.00e-176	610.00
IUUC-Laf-053487	Loxodonta africana	77.49	0.00e+00	886.00
IUUC-Mcc-054682	Macaca mulatta	76.61	0.00e+00	725.00
IUUC-Meu-055937	Macropus eugenii	67.03	2.00e-172	598.00
IUUC-Mga-059953	Meleagris gallopavo	64.25	0.00e+00	737.00
IUUC-Mmr-061743	Microcebus murinus	77.96	0.00e+00	902.00
IUUC-Mdo-062328	Monodelphis domestica	67.74	0.00e+00	776.00
IUUC-Mmu-063979	Mus musculus	77.27	0.00e+00	894.00
IUUC-Mpu-066750	Mustela putorius furo	78.93	0.00e+00	920.00
IUUC-Mlu-066960	Myotis lucifugus	77.63	0.00e+00	898.00
IUUC-Nle-069690	Nomascus leucogenys	77.59	0.00e+00	798.00
IUUC-Opr-071059	Ochotona princeps	72.17	0.00e+00	808.00
IUUC-Ont-072004	Oreochromis niloticus	48.49	1.00e-144	506.00
IUUC-Oan-073172	Ornithorhynchus anatinus	52.20	4.00e-148	518.00
IUUC-Ocu-074310	Oryctolagus cuniculus	68.44	6.00e-85	306.00
IUUC-Ola-086599	Oryzias latipes	48.71	5.00e-149	521.00
IUUC-Oga-087980	Otolemur garnettii	78.12	0.00e+00	905.00
IUUC-Ptr-090598	Pan troglodytes	77.68	0.00e+00	802.00
IUUC-Pan-092387	Papio anubis	70.81	0.00e+00	726.00
IUUC-Psi-093484	Pelodiscus sinensis	65.20	0.00e+00	761.00
IUUC-Pma-094224	Petromyzon marinus	43.49	1.00e-126	447.00
IUUC-Pfo-096149	Poecilia formosa	50.17	1.00e-152	533.00
IUUC-Pab-098097	Pongo abelii	78.93	0.00e+00	921.00
IUUC-Pca-100118	Procavia capensis	83.91	9.00e-172	597.00
IUUC-Pva-103174	Pteropus vampyrus	68.31	1.00e-85	310.00
IUUC-Rno-105350	Rattus norvegicus	77.20	0.00e+00	891.00
IUUC-Sha-106817	Sarcophilus harrisii	56.91	2.00e-66	246.00
IUUC-Sar-113490	Sorex araneus	84.39	3.00e-157	548.00
IUUC-Ssc-115827	Sus scrofa	80.39	0.00e+00	932.00
IUUC-Tgu-116748	Taeniopygia guttata	65.85	0.00e+00	652.00
IUUC-Tru-118644	Takifugu rubripes	48.53	8.00e-146	510.00
IUUC-Tsy-118888	Tarsius syrichta	71.53	0.00e+00	707.00
IUUC-Tni-120060	Tetraodon nigroviridis	46.54	3.00e-127	448.00
IUUC-Ttr-129183	Tursiops truncatus	78.93	0.00e+00	813.00
IUUC-Xtr-132780	Xenopus tropicalis	59.09	0.00e+00	667.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence