iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059599

UUCD1 version

UUC-MeG-00108

Ensembl Protein ID

ENSMGAP00000001672.2

UniProt Accession

G1MTE6; G1MTE6_MELGA

Protein Name

Uncharacterized protein

Gene Name

MID2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002101.2	ENSMGAT00000002336.2	ENSMGAP00000001672.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.70e-07	30.0	12	62

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw......pglknssskefrCPlCr 46
           C+iCle f+d pl+lpC H  +++C +++       g + +   +f+CP+Cr
   Q: 12   CPICLELFED-PLLLPCAHSLCFSCAHRIllsgcsSGESIEPLSAFQCPTCR 62
           **********.999***************776666444444455568****8 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LKMETLESEL TCPICLELFE DPLLLPCAHS LCFSCAHRIL LSGCSSGESI EPLSAFQCPT 60
CRYVISLNHR GLEGLKRNVT LQNIIDRFQK ASLSSPNSPS ESRRDRPYRP NPTMSVGGER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAAGATGG AAACACTGGA GTCCGAATTG ACCTGCCCAA TCTGTCTGGA GTTATTCGAA 60
GATCCTCTGC TTCTGCCCTG CGCCCACAGC CTGTGCTTCA GCTGCGCCCA CCGCATCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR033491--MID2
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00502--BBC
SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005874--C:microtubule
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0035372--P:protein localization to microtubule

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001342	Ailuropoda melanoleuca	82.64	0.00e+00	1220.00
IUUC-Apl-004167	Anas platyrhynchos	85.66	0.00e+00	1232.00
IUUC-Cja-019379	Callithrix jacchus	82.31	0.00e+00	1214.00
IUUC-Cfa-021219	Canis familiaris	85.76	0.00e+00	1222.00
IUUC-Cpo-021954	Cavia porcellus	85.63	0.00e+00	1220.00
IUUC-Csa-023047	Chlorocebus sabaeus	86.23	0.00e+00	1234.00
IUUC-Dre-028003	Danio rerio	75.94	0.00e+00	1081.00
IUUC-Dno-029344	Dasypus novemcinctus	85.90	0.00e+00	1225.00
IUUC-Dor-030160	Dipodomys ordii	73.12	0.00e+00	815.00
IUUC-Eca-033688	Equus caballus	86.19	0.00e+00	1230.00
IUUC-Fca-036427	Felis catus	82.64	0.00e+00	1220.00
IUUC-Fal-036967	Ficedula albicollis	75.29	0.00e+00	975.00
IUUC-Gmo-038518	Gadus morhua	67.67	0.00e+00	756.00
IUUC-Gga-040408	Gallus gallus	87.57	0.00e+00	1288.00
IUUC-Gac-041617	Gasterosteus aculeatus	74.69	0.00e+00	1089.00
IUUC-Ggo-045217	Gorilla gorilla	82.36	0.00e+00	1217.00
IUUC-Hsa-045969	Homo sapiens	82.50	0.00e+00	1218.00
IUUC-Itr-049079	Ictidomys tridecemlineatus	82.73	0.00e+00	1218.00
IUUC-Lch-050468	Latimeria chalumnae	76.98	0.00e+00	1082.00
IUUC-Laf-054029	Loxodonta africana	82.59	0.00e+00	1215.00
IUUC-Mcc-055424	Macaca mulatta	82.64	0.00e+00	1221.00
IUUC-Meu-056432	Macropus eugenii	80.95	0.00e+00	1073.00
IUUC-Mmr-061432	Microcebus murinus	81.94	0.00e+00	1211.00
IUUC-Mdo-061989	Monodelphis domestica	85.80	0.00e+00	1219.00
IUUC-Mmu-063963	Mus musculus	82.45	0.00e+00	1213.00
IUUC-Mpu-065964	Mustela putorius furo	86.09	0.00e+00	1232.00
IUUC-Mlu-067148	Myotis lucifugus	86.09	0.00e+00	1234.00
IUUC-Nle-069552	Nomascus leucogenys	85.94	0.00e+00	1232.00
IUUC-Opr-070968	Ochotona princeps	93.36	4.00e-150	524.00
IUUC-Ont-072260	Oreochromis niloticus	75.37	0.00e+00	922.00
IUUC-Ocu-074109	Oryctolagus cuniculus	85.94	0.00e+00	1231.00
IUUC-Ola-087285	Oryzias latipes	71.09	0.00e+00	963.00
IUUC-Oga-089063	Otolemur garnettii	82.45	0.00e+00	1215.00
IUUC-Oar-089845	Ovis aries	85.94	0.00e+00	1232.00
IUUC-Ptr-091360	Pan troglodytes	82.50	0.00e+00	1218.00
IUUC-Pan-092900	Papio anubis	81.88	0.00e+00	1212.00
IUUC-Pfo-096044	Poecilia formosa	75.37	0.00e+00	918.00
IUUC-Pab-098637	Pongo abelii	86.09	0.00e+00	1233.00
IUUC-Pca-100154	Procavia capensis	91.64	0.00e+00	706.00
IUUC-Pva-102319	Pteropus vampyrus	81.20	0.00e+00	1182.00
IUUC-Rno-105496	Rattus norvegicus	85.94	0.00e+00	1229.00
IUUC-Sha-107246	Sarcophilus harrisii	85.65	0.00e+00	1216.00
IUUC-Ssc-115858	Sus scrofa	86.38	0.00e+00	1239.00
IUUC-Tru-118237	Takifugu rubripes	75.45	0.00e+00	1099.00
IUUC-Tsy-119383	Tarsius syrichta	82.56	0.00e+00	1169.00
IUUC-Tni-119919	Tetraodon nigroviridis	74.86	0.00e+00	1096.00
IUUC-Ttr-128902	Tursiops truncatus	82.59	0.00e+00	1218.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence