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Tag Content
UUCD2 ID IUUC-Cfa-020378
UUCD1 version UUC-CaF-01020
Ensembl Protein ID ENSCAFP00000020178.3
UniProt Accession F1PXC1; F1PXC1_CANLF
Genbank Protein ID ENSCAFP00000020178
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03003483
Gene Name USP28
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000013688.4 ENSCAFT00000021721.4 ENSCAFP00000020175.3
ENSCAFG00000013688.4 ENSCAFT00000021725.3 ENSCAFP00000020178.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 8.60e-58 196.4 140 629
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L+++pe+r+l+l+     +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 140  VGLKNIGNTCWFSAVIQSLFQLPEFRRLVLSyslpqNVLENCPSH-TEKRNIVFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 226
           6******************************96555445555543.3678889******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            + +qqD++Ef++ lld le++++                     +  ++ +k+++++++lF g++ ++ + +        +e+f +++
   Q: 227  PEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVHNPRNKSENPMVQLFYGTFLTEGVREGKPFC--NNETFGQYP 295
           799********************22..................23457899****************99998665555..5899***** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e  +e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 296  LQVNGYR-----NLDECLEGAMVEGDIE----LLPSD--HSVTYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 373
           *******.....99****8776666666....44444..557788999***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++ +                                                                                    
   Q: 374  RYMYKskelirskrecirklkeeikvlqqkleryvkygsgparfplpdmlkyviefastkpasesptcqsdahmtlplssvhcpvsdla 462
           **999888888888888888888888888888888777777777777777777777777777777777777777777777777776666 PP
   S: 268  ......peekqke............................................................................ 274
                 +     e                                                                            
   Q: 463  skestsK-----Esssqdvegtfssedslpesiamnkpltssrstmempaqpaprtvtdeeinfvktclqrwrseieqdiqdlkncias 546
           6555540.....15555667777777777777777777777777788888888888888888888888888888888889999999999 PP
   S: 275  ...............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                          ++ Y+L+av+vH+G+++ GHY+ay++n+ ++ Wl+++D +Vte+++ee ++++       +aY+l+Y 
   Q: 547  ttqtieqmycdpllrQVPYRLHAVLVHEGQANAGHYWAYIYNQPRQvWLKYNDISVTESSWEELERDSYgglrnVSAYCLMYI 629
           999999999999999***************************99999*******************8879************6 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MLLNQLREIT GIQDPSFLHE ALKASNGDIT QAVSLLTEER VKEPSQDTVA TEPSEVEGSA 60
ANKEVLAKVI DLTHDNKDDL QAAIALSLLE SPKIQADGRD LNRMHEAASA ETKRSKRKRC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020378|DUB,USP|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGAGCTGCC AAATGCTGTT AAACCAACTA AGAGAAATCA CAGGCATTCA GGACCCCTCC 60
TTTCTTCATG AAGCTCTGAA GGTTAGTTTC AAGGCCGCTG TTAGCCAACA GGCTTTAAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020378|DUB,USP|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001836 Ailuropoda melanoleuca 96.41 0.00e+00 1438.00
IUUC-Apl-004010 Anas platyrhynchos 64.50 0.00e+00 1395.00
IUUC-Aca-004741 Anolis carolinensis 61.64 0.00e+00 1328.00
IUUC-Ang-009577 Aspergillus niger 37.37 6.00e-12 67.00
IUUC-Ate-010275 Aspergillus terreus 36.11 7.00e-12 66.60
IUUC-Ame-011910 Astyanax mexicanus 44.03 3.00e-178 620.00
IUUC-Bta-013377 Bos taurus 91.36 0.00e+00 1298.00
IUUC-Cja-019977 Callithrix jacchus 92.83 0.00e+00 1357.00
IUUC-Cpo-021817 Cavia porcellus 87.78 0.00e+00 1299.00
IUUC-Csa-023446 Chlorocebus sabaeus 94.65 0.00e+00 2085.00
IUUC-Cho-024717 Choloepus hoffmanni 77.82 0.00e+00 671.00
IUUC-Cme-027167 Cyanidioschyzon merolae 31.98 1.00e-15 79.00
IUUC-Dor-030955 Dipodomys ordii 87.23 0.00e+00 1295.00
IUUC-Ete-032828 Echinops telfairi 84.10 0.00e+00 789.00
IUUC-Eca-034300 Equus caballus 91.09 0.00e+00 1326.00
IUUC-Eeu-034458 Erinaceus europaeus 89.23 0.00e+00 1286.00
IUUC-Fca-035753 Felis catus 88.77 0.00e+00 1961.00
IUUC-Fal-037062 Ficedula albicollis 66.96 0.00e+00 1401.00
IUUC-Gac-041867 Gasterosteus aculeatus 53.85 0.00e+00 1127.00
IUUC-Ggo-045384 Gorilla gorilla 92.96 0.00e+00 1361.00
IUUC-Hsa-046277 Homo sapiens 93.22 0.00e+00 1366.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 86.44 1.00e-172 600.00
IUUC-Loc-052636 Lepisosteus oculatus 63.30 0.00e+00 1380.00
IUUC-Laf-053808 Loxodonta africana 90.42 0.00e+00 1273.00
IUUC-Mcc-055473 Macaca mulatta 94.65 0.00e+00 2084.00
IUUC-Meu-056416 Macropus eugenii 71.50 0.00e+00 1021.00
IUUC-Mga-060011 Meleagris gallopavo 62.18 0.00e+00 1320.00
IUUC-Mmr-060720 Microcebus murinus 89.11 0.00e+00 1269.00
IUUC-Mdo-061955 Monodelphis domestica 86.30 0.00e+00 1833.00
IUUC-Mmu-063870 Mus musculus 86.57 0.00e+00 1295.00
IUUC-Mpu-066454 Mustela putorius furo 95.81 0.00e+00 2038.00
IUUC-Mlu-067487 Myotis lucifugus 85.37 0.00e+00 1254.00
IUUC-Nle-070044 Nomascus leucogenys 93.22 0.00e+00 1364.00
IUUC-Opr-070888 Ochotona princeps 97.83 2.00e-161 563.00
IUUC-Ocu-074523 Oryctolagus cuniculus 88.03 0.00e+00 1296.00
IUUC-Oga-088618 Otolemur garnettii 89.21 0.00e+00 1303.00
IUUC-Oar-089848 Ovis aries 92.61 0.00e+00 2030.00
IUUC-Ptr-091630 Pan troglodytes 91.36 0.00e+00 895.00
IUUC-Pan-092882 Papio anubis 93.82 0.00e+00 1540.00
IUUC-Psi-093422 Pelodiscus sinensis 72.48 0.00e+00 1592.00
IUUC-Pma-094250 Petromyzon marinus 51.54 6.00e-80 290.00
IUUC-Pno-095093 Phaeosphaeria nodorum 31.86 9.00e-12 66.20
IUUC-Pab-098337 Pongo abelii 92.95 0.00e+00 1359.00
IUUC-Pca-100901 Procavia capensis 68.44 0.00e+00 947.00
IUUC-Pva-102226 Pteropus vampyrus 84.36 0.00e+00 1115.00
IUUC-Rno-105735 Rattus norvegicus 89.23 0.00e+00 1987.00
IUUC-Sha-107489 Sarcophilus harrisii 85.43 0.00e+00 1282.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 35.80 1.00e-09 59.30
IUUC-Sar-112977 Sorex araneus 76.51 0.00e+00 821.00
IUUC-Ssc-115463 Sus scrofa 91.14 0.00e+00 1096.00
IUUC-Tsy-118971 Tarsius syrichta 95.61 0.00e+00 630.00
IUUC-Tni-119983 Tetraodon nigroviridis 53.47 0.00e+00 1130.00
IUUC-Ttr-128887 Tursiops truncatus 84.15 0.00e+00 1199.00
IUUC-Vpa-130614 Vicugna pacos 90.52 0.00e+00 898.00
Created Date 25-Jun-2017

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