iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cme-027167

Ensembl Protein ID

CMC070CT

UniProt Accession

M1V6K2; M1V6K2_CYAM1

Genbank Protein ID

BAM79009.1

Protein Name

Similar to ubiquitin-specific processing protease Ubp2p

Genbank Nucleotide ID

AP006485

Gene Name

CYME_CMC070C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CMC070C	CMC070CT	CMC070CT

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.70e-49	165.4	259	754

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee..fsgyeqqDaqEflafll 100
           Gl N+gNtCY+NS+LQ+ +++p++ + +++  + +++ e+ + +  +++++lq+lf+ l+ s++++ +p+ +l al+++ ++  ++  +q+D +Ef + +l
   Q: 259  GLCNVGNTCYLNSLLQVYYHTPSFVRRVFSWREDRVDTEKTPPKAIDVVRELQRLFAYLLLSERRYADPTGFLYALAETLNSaaLDLGAQHDLSEFNETFL 359
           9*****************************9999****9999999****************************9999877664577*************** PP
   S: 101  dqleeelkkeknkpkeeeeeedkselsde...............................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
            ++e +l+  +n++  + + ++  +  +e                               a++++  + +  ++ +++    s ++  + +     e +  
   Q: 360  RSIEAALQTVDNTEPLQRTFTH--SFVQElhcrvmegahqvamavemnpqcssdgsgthgAPQSPGASDTPALDAMLER--LSGLQSATWRLADRVEGTTS 456
           *******442222222222222..2222234556666666666666666666666666554444444444444444433..23333333334444444555 PP
   S: 171  dlslpvpgkeetkkeslqdcLesft......keeelegenkyycekckkkqe................aekklklkklPevLilhLkRfsfseeqksreki 249
            l l+v + + +   +l  +L++++      ++e+l+    ++ ++  ++++                a+k++++++l +vL + L+R +f++e++++ek+
   Q: 457  ALILDVASGNCR---DLYAALDEYVladveyQPEKLTPGTPIHADSNPSDTQastsgittapttntrtATKSVWFQTLAPVLFIYLQRLRFNQETHMPEKV 554
           555555555555...89999988864333346666666666666666655556666666666666666********************************* PP
   S: 250  nkkvefpleLdlspfcts......................................................................peekqke...... 274
           n+ ++f +++ l++++++                                                                            +      
   Q: 555  NDFFDFAETIYLDRYLERnreaallarlqdaqycreyaqleqelqrllhlpglqepsdvvyeavlerlraldpgnsshppvvvdqsetA-----Hreqale 650
           ******************77777777777777777777777777766666666666666666666666666666666666665555550.....0555555 PP
   S: 275  ...................................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlf 334
                                              ++ Y+L av+vH+G ++ GHY++++++++ + W++f+D++V+ v++e v +  +     ++aY l+
   Q: 651  slsyvyvtekqqrerletrmaclaeemvqnfaslsNEAYRLQAVLVHEGAPEAGHYFVFIRSTRAGdWYEFNDQRVRRVSWEHVHSVGRggpgtASAYALL 751
           66666666666666788888888888888888888***************************77667*******************7779*********** PP
   S: 335  Ykr 337
           Y+r
   Q: 752  YRR 754
           *98 PP

Organism

Cyanidioschyzon merolae

Protein Sequence
(Fasta)

LLLRRCREHC GVDRIQNTQV FRLVVARATG CFGLFPQMRN IFAKTRSENS SQRNSSANVR 60
DRPTAVRETG SSQTKRMEVW KLAAELGFTD AQVAVALKHG CHSTEQILDY ILTHKIRPDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTTGCTAC GAAGGTGCCG CGAACACTGC GGCGTCGACC GCATCCAGAA CACTCAGGTT 60
TTCCGTTTAG TTGTTGCCCG AGCGACTGGA TGTTTTGGAC TTTTCCCGCA GATGCGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF02809--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cme:CYME_CMC070C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	33.50	1.00e-16	80.10
IUUC-Apl-004030	Anas platyrhynchos	31.34	7.00e-14	70.90
IUUC-Aca-004741	Anolis carolinensis	31.43	4.00e-14	71.60
IUUC-Ago-007865	Ashbya gossypii	33.33	2.00e-09	56.20
IUUC-Acl-008164	Aspergillus clavatus	27.83	3.00e-12	65.90
IUUC-Afu-008871	Aspergillus fumigatus	29.76	2.00e-11	62.40
IUUC-Ani-009503	Aspergillus nidulans	28.21	1.00e-12	67.00
IUUC-Ang-009577	Aspergillus niger	27.73	5.00e-13	68.20
IUUC-Ate-010275	Aspergillus terreus	27.45	3.00e-14	72.00
IUUC-Bgr-011993	Blumeria graminis	23.92	8.00e-10	57.40
IUUC-Bta-013377	Bos taurus	33.50	1.00e-16	79.70
IUUC-Bci-013999	Botrytis cinerea	26.52	6.00e-16	78.20
IUUC-Cel-018269	Caenorhabditis elegans	37.68	2.00e-09	55.10
IUUC-Cja-019977	Callithrix jacchus	32.84	2.00e-16	79.00
IUUC-Cfa-020378	Canis familiaris	31.98	2.00e-16	79.30
IUUC-Cpo-021817	Cavia porcellus	32.32	2.00e-16	79.70
IUUC-Csa-023446	Chlorocebus sabaeus	33.00	2.00e-16	79.70
IUUC-Cho-024343	Choloepus hoffmanni	46.88	7.00e-13	67.00
IUUC-Cin-025302	Ciona intestinalis	28.79	4.00e-15	73.90
IUUC-Dre-028105	Danio rerio	33.33	2.00e-14	73.20
IUUC-Dno-029495	Dasypus novemcinctus	23.78	7.00e-15	74.30
IUUC-Dor-030948	Dipodomys ordii	48.44	4.00e-13	68.20
IUUC-Dse-031290	Dothistroma septosporum	25.73	2.00e-10	59.30
IUUC-Eca-034300	Equus caballus	32.85	3.00e-15	75.50
IUUC-Eeu-034458	Erinaceus europaeus	32.49	1.00e-16	79.70
IUUC-Fca-035876	Felis catus	26.03	4.00e-21	94.70
IUUC-Fal-037062	Ficedula albicollis	31.97	1.00e-13	70.10
IUUC-Fso-038114	Fusarium solani	25.58	5.00e-10	58.20
IUUC-Gmo-039593	Gadus morhua	34.48	8.00e-13	67.40
IUUC-Gga-040878	Gallus gallus	26.15	5.00e-16	77.80
IUUC-Gac-041867	Gasterosteus aculeatus	31.19	6.00e-17	80.90
IUUC-Ggo-045384	Gorilla gorilla	32.34	1.00e-15	76.60
IUUC-Hsa-046277	Homo sapiens	33.00	2.00e-16	79.30
IUUC-Itr-048276	Ictidomys tridecemlineatus	35.71	5.00e-13	67.00
IUUC-Kpa-049349	Komagataella pastoris	25.10	8.00e-16	77.40
IUUC-Loc-052636	Lepisosteus oculatus	30.08	2.00e-17	82.80
IUUC-Lma-053078	Leptosphaeria maculans	25.23	1.00e-12	67.00
IUUC-Laf-053808	Loxodonta africana	31.60	3.00e-16	78.20
IUUC-Mcc-055473	Macaca mulatta	33.00	1.00e-16	79.70
IUUC-Mga-059808	Meleagris gallopavo	31.19	8.00e-14	70.50
IUUC-Mmr-060987	Microcebus murinus	24.94	4.00e-16	78.20
IUUC-Mdo-061955	Monodelphis domestica	30.88	3.00e-14	72.80
IUUC-Mmu-063870	Mus musculus	33.83	4.00e-17	81.60
IUUC-Mpu-066454	Mustela putorius furo	32.49	1.00e-16	79.70
IUUC-Mlu-067139	Myotis lucifugus	24.71	2.00e-15	76.30
IUUC-Nfi-068458	Neosartorya fischeri	30.81	8.00e-14	70.90
IUUC-Nle-070044	Nomascus leucogenys	33.00	2.00e-16	79.30
IUUC-Opr-070214	Ochotona princeps	41.56	6.00e-13	67.80
IUUC-Ont-072386	Oreochromis niloticus	33.03	5.00e-17	81.60
IUUC-Oan-073054	Ornithorhynchus anatinus	31.50	3.00e-14	71.60
IUUC-Ocu-074523	Oryctolagus cuniculus	32.04	7.00e-15	73.90
IUUC-Ola-086393	Oryzias latipes	30.43	1.00e-15	76.60
IUUC-Oga-088618	Otolemur garnettii	30.96	1.00e-15	76.60
IUUC-Oar-090266	Ovis aries	25.86	1.00e-20	93.20
IUUC-Ptr-090546	Pan troglodytes	24.94	6.00e-16	77.80
IUUC-Pan-092311	Papio anubis	24.94	5.00e-16	77.80
IUUC-Psi-093459	Pelodiscus sinensis	31.34	3.00e-14	71.20
IUUC-Pno-095093	Phaeosphaeria nodorum	26.45	4.00e-13	68.20
IUUC-Pfo-096466	Poecilia formosa	32.58	2.00e-17	82.80
IUUC-Pab-098337	Pongo abelii	33.00	2.00e-16	79.30
IUUC-Pca-100718	Procavia capensis	48.44	6.00e-13	67.40
IUUC-Pva-102226	Pteropus vampyrus	35.42	3.00e-13	68.60
IUUC-Rno-105735	Rattus norvegicus	31.53	8.00e-16	77.40
IUUC-Sce-106441	Saccharomyces cerevisiae	24.30	5.00e-14	71.60
IUUC-Sha-107051	Sarcophilus harrisii	26.71	6.00e-21	94.40
IUUC-Sja-107936	Schizosaccharomyces japonicus	24.84	3.00e-11	62.40
IUUC-Spo-108381	Schizosaccharomyces pombe	27.39	1.00e-11	63.20
IUUC-Ssl-108532	Sclerotinia sclerotiorum	25.94	1.00e-14	73.60
IUUC-Sar-112977	Sorex araneus	30.43	2.00e-16	79.30
IUUC-Ssc-115877	Sus scrofa	24.94	6.00e-16	77.40
IUUC-Tgu-117473	Taeniopygia guttata	31.34	9.00e-14	70.50
IUUC-Tru-117807	Takifugu rubripes	28.84	2.00e-21	95.90
IUUC-Tsy-118971	Tarsius syrichta	33.14	2.00e-14	72.40
IUUC-Tni-119983	Tetraodon nigroviridis	26.62	2.00e-30	125.00
IUUC-Tme-126928	Tuber melanosporum	25.99	2.00e-16	79.70
IUUC-Tbe-127549	Tupaia belangeri	42.86	3.00e-13	68.60
IUUC-Ttr-128896	Tursiops truncatus	28.32	6.00e-14	71.20
IUUC-Vda-129742	Verticillium dahliae	38.96	3.00e-08	52.40
IUUC-Vpa-130500	Vicugna pacos	30.35	9.00e-14	70.50
IUUC-Xtr-132436	Xenopus tropicalis	28.28	1.00e-19	90.10
IUUC-Xma-133995	Xiphophorus maculatus	32.58	9.00e-18	84.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence