iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052636

Ensembl Protein ID

ENSLOCP00000005467.1

UniProt Accession

W5MAQ8; W5MAQ8_LEPOC

Genbank Protein ID

ENSLOCP00000005467

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01018527

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000004503.1	ENSLOCT00000005452.1	ENSLOCP00000005444.1
ENSLOCG00000004503.1	ENSLOCT00000005475.1	ENSLOCP00000005467.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.40e-60	203.3	225	715

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +Gl+N+gNtC++ +v+Q+L+++p++r+l+l+     +  ek++   +++++ +++++l+ lf+ ++ s+++ v+p++ ++ lk++ +  
   Q: 225  VGLRNVGNTCWFSAVIQSLFHLPKFRRLVLNytlsqSILEKCRSH-SEKRNIAFMQELRCLFALMVGSSRRFVDPSAAVELLKDAFRT- 311
           6******************************98887677777665.479999*******************************99986. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           s+ +qqD++Ef++ lld le++++                     + ++++ k+++++++lF g++  +    + +++ s  e+f +++
   Q: 312  SEAQQQDVSEFTHKLLDWLEDAFQL------------------AANGNNPEAKQQNPMVQLFYGTFVAE--RSHEGKTLSNIEQFGQYP 380
           99*********************22..................235678999**************965..5567788899******** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e e+e    +++++      + ++ +++klP+vL+++L+Rf+f+++ +++eki+kk+efp+ + ++
   Q: 381  LQVNGFN-----NLDECLEGAMVEGEIET---LHSDQTV---HSGQERWFSKLPPVLTFELSRFEFNQSLGRPEKIHKKLEFPQVIYMD 458
           *******.....9*****99999999995...6776665...456789***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++++                                                                                    
   Q: 459  RYLHRnkelirkrrreakklkdqltalqqklesynsygsgpakypladmlqyvlefattkpssvspaedirmisppstaspdttthtdp 547
           *****777777777777777777777777777777777776666666666666666666666666666666666666666655555555 PP
   S: 268  ..peekqke................................................................................ 274
             +     +                                                                                
   Q: 548  apE-----Ntslseaedsgtpdclsspappgqrtpiykpftqcrplvewpsqpaphsvseeelqfvegclqrwraeveqniqelkesid 631
           550.....055555555666666666666666666666666666666666666666666667777777777777777777777788888 PP
   S: 275  ................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                           ++ Y+L+av+vH+G++s GHY+ay+ +++ k Wl+++D +V+e+++ee ++++      ++aY+l+Y 
   Q: 632  risrqlegmysdaslsQVPYRLHAVLVHEGQASAGHYWAYICDHSSKlWLKYNDISVSESTWEELEKDSYggmknASAYCLMYI 715
           8888888888888888***************************88889*******************8879************6 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MHATGTLLSP PHAVRGHARR KRARSSSWAD EPRGRAWRVG DGWRRRESEA GGEGFIENYR 60
KKRRIWSIAM TAEQQCDHGD NSGSSTHVLI NQLREITGTQ DVEILQRVLK ASNGDMSQAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAAGTTAAC CTGCCTGCTC AGCTACTGCG CACGATGCAC GCGACGGGGA CGTTATTGTC 60
ACCTCCCCAC GCAGTACGTG GGCATGCACG TCGCAAGCGC GCTCGTTCTT CATCCTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004741	Anolis carolinensis	55.15	0.00e+00	1193.00
IUUC-Ani-009503	Aspergillus nidulans	34.86	6.00e-13	70.10
IUUC-Ang-009577	Aspergillus niger	36.64	1.00e-12	69.30
IUUC-Ame-011910	Astyanax mexicanus	61.21	9.00e-168	585.00
IUUC-Cfa-020378	Canis familiaris	63.30	0.00e+00	1400.00
IUUC-Cpo-021817	Cavia porcellus	59.64	0.00e+00	859.00
IUUC-Csa-023446	Chlorocebus sabaeus	63.46	0.00e+00	1407.00
IUUC-Cme-027167	Cyanidioschyzon merolae	30.08	1.00e-16	82.40
IUUC-Dre-028105	Danio rerio	72.67	0.00e+00	957.00
IUUC-Ete-032828	Echinops telfairi	57.20	5.00e-148	518.00
IUUC-Fal-037062	Ficedula albicollis	60.26	0.00e+00	1260.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	70.71	6.00e-127	447.00
IUUC-Lma-053078	Leptosphaeria maculans	27.84	2.00e-11	65.50
IUUC-Laf-053808	Loxodonta africana	61.14	0.00e+00	816.00
IUUC-Mcc-055473	Macaca mulatta	63.46	0.00e+00	1407.00
IUUC-Mdo-061955	Monodelphis domestica	62.59	0.00e+00	1318.00
IUUC-Mmu-063870	Mus musculus	59.92	0.00e+00	886.00
IUUC-Mpu-066454	Mustela putorius furo	62.97	0.00e+00	1345.00
IUUC-Opr-070888	Ochotona princeps	72.92	2.00e-120	427.00
IUUC-Ont-072386	Oreochromis niloticus	68.25	0.00e+00	955.00
IUUC-Oar-089848	Ovis aries	62.54	0.00e+00	1360.00
IUUC-Pan-092882	Papio anubis	62.73	0.00e+00	1048.00
IUUC-Psi-093422	Pelodiscus sinensis	62.90	0.00e+00	1385.00
IUUC-Pma-094250	Petromyzon marinus	49.31	6.00e-77	280.00
IUUC-Pno-095093	Phaeosphaeria nodorum	43.42	3.00e-12	67.40
IUUC-Pfo-096466	Poecilia formosa	69.89	0.00e+00	978.00
IUUC-Rno-105735	Rattus norvegicus	63.18	0.00e+00	1387.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	34.18	6.00e-10	60.10
IUUC-Uma-129338	Ustilago maydis	24.62	5.00e-13	70.90
IUUC-Xma-133995	Xiphophorus maculatus	70.32	0.00e+00	952.00
IUUC-Yli-134560	Yarrowia lipolytica	31.85	2.00e-13	72.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence