iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033824

Ensembl Protein ID

ENSECAP00000022689.1

UniProt Accession

F6Q4M2; F6Q4M2_HORSE

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000025103.1	ENSECAT00000027122.1	ENSECAP00000022689.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.60e-14	51.6	367	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 367  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 421
           689********************9999.999********7.99************86 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAPEEDAGGE ALEGSFWEAG NYRRTVQRVE DGHRLCGDLV SCFQERARIE KAYAQQLADW 60
ARKWRGAVEK GPQYGTLEKA WHAFFTAAER LSVLHLEVRE KLQGQDSERV RAWQRGAFHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGACTCAC AGTGGCAGCT CTGAGAGGTG GACGGCCAGG TCCCTGAACT GATCTCTAGG 60
CCCCCAGGTA TGTGGGGTGA AGTGGAGGGG AAGGGCAGAC CCCGGTGAGA GGAGGAGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

KEGG

ecb:100057860

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	94.89	0.00e+00	648.00
IUUC-Apl-003211	Anas platyrhynchos	64.85	8.00e-177	613.00
IUUC-Aca-004256	Anolis carolinensis	64.62	9.00e-174	602.00
IUUC-Ame-011049	Astyanax mexicanus	60.36	2.00e-152	531.00
IUUC-Bta-013322	Bos taurus	90.93	0.00e+00	746.00
IUUC-Cja-018907	Callithrix jacchus	94.58	0.00e+00	773.00
IUUC-Cfa-021126	Canis familiaris	94.34	0.00e+00	766.00
IUUC-Cpo-021491	Cavia porcellus	91.98	0.00e+00	756.00
IUUC-Csa-023107	Chlorocebus sabaeus	95.52	0.00e+00	776.00
IUUC-Dre-027933	Danio rerio	58.37	2.00e-143	502.00
IUUC-Dno-029002	Dasypus novemcinctus	95.28	0.00e+00	745.00
IUUC-Eeu-035122	Erinaceus europaeus	84.70	1.00e-171	595.00
IUUC-Fca-036420	Felis catus	96.23	0.00e+00	821.00
IUUC-Fal-037277	Ficedula albicollis	64.77	1.00e-177	615.00
IUUC-Gga-040941	Gallus gallus	65.65	1.00e-178	619.00
IUUC-Gac-041374	Gasterosteus aculeatus	62.50	2.00e-142	498.00
IUUC-Ggo-045211	Gorilla gorilla	95.05	0.00e+00	773.00
IUUC-Hsa-046053	Homo sapiens	95.52	0.00e+00	776.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	93.87	0.00e+00	767.00
IUUC-Loc-052808	Lepisosteus oculatus	61.05	1.00e-153	536.00
IUUC-Laf-054211	Loxodonta africana	93.63	0.00e+00	744.00
IUUC-Mcc-055044	Macaca mulatta	95.52	0.00e+00	776.00
IUUC-Mga-059216	Meleagris gallopavo	65.58	6.00e-179	620.00
IUUC-Mmr-061172	Microcebus murinus	95.28	0.00e+00	780.00
IUUC-Mdo-062600	Monodelphis domestica	87.03	0.00e+00	754.00
IUUC-Mmu-063218	Mus musculus	92.92	0.00e+00	762.00
IUUC-Mpu-066819	Mustela putorius furo	95.20	0.00e+00	650.00
IUUC-Mlu-067597	Myotis lucifugus	90.95	0.00e+00	778.00
IUUC-Nle-069195	Nomascus leucogenys	94.81	0.00e+00	771.00
IUUC-Opr-071050	Ochotona princeps	94.35	0.00e+00	768.00
IUUC-Oan-073256	Ornithorhynchus anatinus	87.09	0.00e+00	728.00
IUUC-Ocu-074653	Oryctolagus cuniculus	95.05	0.00e+00	744.00
IUUC-Oga-089040	Otolemur garnettii	93.40	0.00e+00	773.00
IUUC-Oar-089918	Ovis aries	94.88	0.00e+00	755.00
IUUC-Ptr-091307	Pan troglodytes	95.52	0.00e+00	776.00
IUUC-Pan-092512	Papio anubis	95.52	0.00e+00	776.00
IUUC-Pfo-096881	Poecilia formosa	59.55	1.00e-151	529.00
IUUC-Pab-098620	Pongo abelii	95.52	0.00e+00	776.00
IUUC-Pva-102464	Pteropus vampyrus	93.16	0.00e+00	754.00
IUUC-Rno-106091	Rattus norvegicus	91.98	0.00e+00	755.00
IUUC-Sha-107474	Sarcophilus harrisii	88.92	0.00e+00	758.00
IUUC-Ssc-116128	Sus scrofa	94.58	0.00e+00	779.00
IUUC-Tgu-117511	Taeniopygia guttata	61.68	2.00e-172	598.00
IUUC-Tru-118005	Takifugu rubripes	59.73	8.00e-139	486.00
IUUC-Tni-119851	Tetraodon nigroviridis	65.70	2.00e-143	501.00
IUUC-Ttr-129313	Tursiops truncatus	94.81	0.00e+00	806.00
IUUC-Vpa-130760	Vicugna pacos	98.91	1.00e-102	366.00
IUUC-Xtr-132697	Xenopus tropicalis	57.18	2.00e-135	475.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence