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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063484
UUCD1 version UUC-MuM-00211
Ensembl Protein ID ENSMUSP00000031696.3
UniProt Accession Q8VHS6; Q8CDP8; ASB15_MOUSE
Genbank Protein ID AAL57362.1; BAC26602.1; EDL13821.1; AAH50794.1
Protein Name Ankyrin repeat and SOCS box protein 15
Genbank Nucleotide ID AF403043; AK029759; AC153635; BC050794
Gene Name Asb15
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000029685.15 ENSMUST00000031696.9 ENSMUSP00000031696.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IIDPINAHINTMentha
Post-translational Modifications (PTMs)
CPLMPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 2.40e-17 63.6 524 578
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box
   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrl...kaidkLPLPksLkdYLlyedy 52
           + +++++ ++p+SL+hLCRl+Irr +g qrl   ++i+ LPLP ++++YLl +++
   Q: 524  WPEIRQIIENPCSLKHLCRLKIRRVMGLQRLcqpASIQMLPLPAAMRRYLLFKEF 578
           56899999*******************************************9987 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Sequence
(Fasta)
MDINDDSNDD HLASYDIQLC IQESIEASQA IFHPKRLVQL SDQNRKLVEA IRQGRIFELQ 60
EYVQYKYALE EADEKGWFPL HEAVVQPIQQ ILETVLDASY KTLWEFKTCD GETPLTLAVK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063484|E3,SOCS|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGAATGTGGA ATCATGGCTT TATAAAAGAT GCATGTGTTC TTTGTAACTT TGGATTCAAG 60
CGTCTGCATG GCAGTATTTG CTAAAGACAT CGAGAGTAGA CAGACTTGAC TGATCCAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063484|E3,SOCS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001496--SOCS_box
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50225--SOCS
Pfam

PF12796--Ank_2
PF07525--SOCS_box
PRINTS

PR01415--ANKYRIN
SMART

SM00248--ANK
SM00253--SOCS
SM00969--SOCS_box
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035556--P:intracellular signal transduction
KEGG mmu:78910
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002210 Ailuropoda melanoleuca 86.96 0.00e+00 1078.00
IUUC-Apl-003801 Anas platyrhynchos 75.00 0.00e+00 917.00
IUUC-Aca-005290 Anolis carolinensis 69.41 0.00e+00 912.00
IUUC-Ame-011590 Astyanax mexicanus 54.89 2.00e-166 578.00
IUUC-Bta-013427 Bos taurus 87.82 0.00e+00 1091.00
IUUC-Cja-019662 Callithrix jacchus 89.19 0.00e+00 1102.00
IUUC-Cfa-021155 Canis familiaris 88.48 0.00e+00 1076.00
IUUC-Csa-023294 Chlorocebus sabaeus 88.51 0.00e+00 996.00
IUUC-Cho-024744 Choloepus hoffmanni 78.38 0.00e+00 884.00
IUUC-Dre-027559 Danio rerio 52.98 2.00e-175 608.00
IUUC-Dno-030076 Dasypus novemcinctus 87.54 0.00e+00 1081.00
IUUC-Dor-030347 Dipodomys ordii 76.27 0.00e+00 800.00
IUUC-Ete-032284 Echinops telfairi 77.97 0.00e+00 853.00
IUUC-Eca-034197 Equus caballus 81.65 0.00e+00 1008.00
IUUC-Eeu-034617 Erinaceus europaeus 81.03 0.00e+00 820.00
IUUC-Fca-035649 Felis catus 87.99 0.00e+00 1095.00
IUUC-Gga-040848 Gallus gallus 73.24 0.00e+00 891.00
IUUC-Gac-041696 Gasterosteus aculeatus 48.45 2.00e-126 446.00
IUUC-Ggo-044907 Gorilla gorilla 88.34 0.00e+00 1096.00
IUUC-Hsa-046111 Homo sapiens 88.51 0.00e+00 1095.00
IUUC-Itr-048869 Ictidomys tridecemlineatus 88.97 0.00e+00 1076.00
IUUC-Lch-050248 Latimeria chalumnae 66.55 0.00e+00 822.00
IUUC-Loc-052752 Lepisosteus oculatus 57.65 0.00e+00 677.00
IUUC-Laf-054585 Loxodonta africana 86.45 0.00e+00 1064.00
IUUC-Mcc-054651 Macaca mulatta 88.34 0.00e+00 1093.00
IUUC-Meu-056277 Macropus eugenii 89.94 2.00e-169 589.00
IUUC-Mtr-058049 Medicago truncatula 27.13 2.00e-17 84.70
IUUC-Mga-060130 Meleagris gallopavo 73.63 0.00e+00 899.00
IUUC-Mmr-060879 Microcebus murinus 88.68 0.00e+00 1097.00
IUUC-Mdo-061877 Monodelphis domestica 83.53 0.00e+00 1035.00
IUUC-Mpu-066536 Mustela putorius furo 87.65 0.00e+00 1087.00
IUUC-Mlu-067317 Myotis lucifugus 87.82 0.00e+00 1078.00
IUUC-Nle-069895 Nomascus leucogenys 88.68 0.00e+00 1093.00
IUUC-Opr-070602 Ochotona princeps 74.16 0.00e+00 671.00
IUUC-Ont-071779 Oreochromis niloticus 49.63 7.00e-146 510.00
IUUC-Oan-073430 Ornithorhynchus anatinus 79.66 0.00e+00 991.00
IUUC-Ocu-073921 Oryctolagus cuniculus 87.48 0.00e+00 1084.00
IUUC-Ola-087235 Oryzias latipes 46.22 3.00e-151 528.00
IUUC-Oga-089182 Otolemur garnettii 87.14 0.00e+00 1086.00
IUUC-Oar-089655 Ovis aries 87.31 0.00e+00 1090.00
IUUC-Ptr-090671 Pan troglodytes 88.34 0.00e+00 1093.00
IUUC-Pan-091931 Papio anubis 88.16 0.00e+00 1093.00
IUUC-Psi-093364 Pelodiscus sinensis 77.61 0.00e+00 959.00
IUUC-Pfo-097338 Poecilia formosa 47.61 1.00e-148 520.00
IUUC-Pab-098552 Pongo abelii 88.34 0.00e+00 1093.00
IUUC-Pca-100415 Procavia capensis 71.75 0.00e+00 783.00
IUUC-Pva-103077 Pteropus vampyrus 89.14 0.00e+00 675.00
IUUC-Rno-104893 Rattus norvegicus 95.20 0.00e+00 1161.00
IUUC-Sha-106824 Sarcophilus harrisii 82.71 0.00e+00 1014.00
IUUC-Sar-113300 Sorex araneus 75.00 0.00e+00 669.00
IUUC-Ssc-115956 Sus scrofa 87.99 0.00e+00 1090.00
IUUC-Tru-117639 Takifugu rubripes 47.77 2.00e-152 532.00
IUUC-Tsy-119263 Tarsius syrichta 90.40 0.00e+00 686.00
IUUC-Tni-120083 Tetraodon nigroviridis 49.44 5.00e-150 524.00
IUUC-Tur-126247 Triticum urartu 25.31 3.00e-16 80.50
IUUC-Tbe-127228 Tupaia belangeri 82.85 0.00e+00 992.00
IUUC-Ttr-128657 Tursiops truncatus 79.25 0.00e+00 964.00
IUUC-Vpa-130435 Vicugna pacos 87.48 0.00e+00 1090.00
IUUC-Xtr-132951 Xenopus tropicalis 66.84 0.00e+00 794.00
Created Date 25-Jun-2017

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