iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022414

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02013913

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008235.3	ENSCPOT00000008310.2	ENSCPOP00000007404.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.30e-16	60.2	153	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ +SLqhLCRl+I+rc+g+     i++LPLP +LkdYL+++++q
   Q: 153  TKPLYTSAPSLQHLCRLTINRCTGT-----IWGLPLPTRLKDYLEEYKFQ 197
           678999*******************.....8***************9886 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MTLRCLEPSG NGAEGTHSQW GTAGSTEEPS PEAARLAKAL RELGYTGWYW GSMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGC GGTGCCTCGA GCCCTCCGGG AATGGCGCGG AAGGGACACA CAGCCAGTGG 60
GGGACAGCAG GGTCGACCGA AGAGCCGTCC CCGGAGGCGG CGCGTCTGGC GAAGGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	95.45	2.00e-104	370.00
IUUC-Apl-003484	Anas platyrhynchos	80.39	8.00e-73	265.00
IUUC-Aca-004253	Anolis carolinensis	72.56	1.00e-71	262.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	2.40e-02	33.10
IUUC-Ame-011267	Astyanax mexicanus	61.68	2.00e-58	218.00
IUUC-Bta-013183	Bos taurus	94.44	1.00e-98	352.00
IUUC-Bra-017915	Brassica rapa	33.90	4.50e-02	32.00
IUUC-Cja-018862	Callithrix jacchus	95.96	2.00e-100	357.00
IUUC-Cfa-020226	Canis familiaris	94.42	2.00e-96	344.00
IUUC-Csa-023758	Chlorocebus sabaeus	95.45	3.00e-104	370.00
IUUC-Cho-024471	Choloepus hoffmanni	86.18	1.00e-71	261.00
IUUC-Dre-028288	Danio rerio	56.48	6.00e-63	233.00
IUUC-Dno-029036	Dasypus novemcinctus	95.96	5.00e-106	376.00
IUUC-Dor-030447	Dipodomys ordii	98.01	6.00e-87	312.00
IUUC-Ete-033023	Echinops telfairi	92.42	4.00e-108	383.00
IUUC-Eca-033422	Equus caballus	41.71	4.00e-41	160.00
IUUC-Eeu-034806	Erinaceus europaeus	40.76	2.00e-39	155.00
IUUC-Fca-036469	Felis catus	96.46	3.00e-100	357.00
IUUC-Fal-036642	Ficedula albicollis	78.95	1.00e-70	258.00
IUUC-Gmo-039331	Gadus morhua	53.17	3.00e-35	140.00
IUUC-Gga-040809	Gallus gallus	77.36	9.00e-73	265.00
IUUC-Gac-041398	Gasterosteus aculeatus	56.61	6.00e-59	219.00
IUUC-Ggo-045341	Gorilla gorilla	96.46	1.00e-100	358.00
IUUC-Hsa-046557	Homo sapiens	95.96	1.00e-112	398.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	82.21	1.00e-92	332.00
IUUC-Lch-050160	Latimeria chalumnae	62.42	8.00e-50	189.00
IUUC-Loc-051825	Lepisosteus oculatus	56.25	1.00e-60	225.00
IUUC-Laf-053560	Loxodonta africana	93.94	7.00e-97	345.00
IUUC-Mcc-055890	Macaca mulatta	95.45	1.00e-99	354.00
IUUC-Meu-056218	Macropus eugenii	79.80	6.00e-95	339.00
IUUC-Mga-059755	Meleagris gallopavo	69.19	8.00e-72	262.00
IUUC-Mmr-061387	Microcebus murinus	95.96	1.00e-103	368.00
IUUC-Mdo-062383	Monodelphis domestica	80.81	8.00e-95	338.00
IUUC-Mmu-063443	Mus musculus	92.93	3.00e-100	357.00
IUUC-Mpu-066459	Mustela putorius furo	94.95	1.00e-98	351.00
IUUC-Mlu-068040	Myotis lucifugus	94.95	9.00e-105	372.00
IUUC-Nle-069016	Nomascus leucogenys	91.41	8.00e-98	348.00
IUUC-Opr-071087	Ochotona princeps	87.88	3.00e-102	363.00
IUUC-Ont-072340	Oreochromis niloticus	56.77	2.00e-59	221.00
IUUC-Oan-073443	Ornithorhynchus anatinus	78.79	5.00e-90	323.00
IUUC-Ocu-074539	Oryctolagus cuniculus	94.42	6.00e-98	349.00
IUUC-Ola-087004	Oryzias latipes	60.76	1.00e-55	208.00
IUUC-Oga-088438	Otolemur garnettii	96.46	4.00e-105	373.00
IUUC-Oar-089932	Ovis aries	94.44	2.00e-98	350.00
IUUC-Ptr-091037	Pan troglodytes	96.46	1.00e-100	358.00
IUUC-Pan-092767	Papio anubis	95.96	3.00e-100	357.00
IUUC-Psi-093099	Pelodiscus sinensis	77.36	1.00e-73	268.00
IUUC-Pma-094671	Petromyzon marinus	48.39	1.00e-36	145.00
IUUC-Pfo-097073	Poecilia formosa	50.52	4.00e-55	207.00
IUUC-Pab-098319	Pongo abelii	95.96	8.00e-106	375.00
IUUC-Pca-101117	Procavia capensis	92.42	5.00e-98	349.00
IUUC-Pva-102117	Pteropus vampyrus	94.95	3.00e-97	347.00
IUUC-Rno-105913	Rattus norvegicus	92.42	6.00e-100	356.00
IUUC-Sha-106500	Sarcophilus harrisii	80.71	3.00e-93	333.00
IUUC-Sar-113001	Sorex araneus	42.18	9.00e-42	163.00
IUUC-Ssc-115252	Sus scrofa	95.96	9.00e-105	372.00
IUUC-Tgu-117524	Taeniopygia guttata	76.10	4.00e-70	256.00
IUUC-Tru-118511	Takifugu rubripes	40.12	8.00e-26	109.00
IUUC-Tsy-119335	Tarsius syrichta	94.70	1.00e-84	305.00
IUUC-Tni-120263	Tetraodon nigroviridis	54.79	2.00e-56	211.00
IUUC-Tca-121866	Theobroma cacao	40.48	2.70e-02	33.10
IUUC-Tbe-127915	Tupaia belangeri	93.43	9.00e-95	338.00
IUUC-Ttr-128372	Tursiops truncatus	95.45	3.00e-104	370.00
IUUC-Vpa-130422	Vicugna pacos	98.01	8.00e-87	311.00
IUUC-Xtr-132941	Xenopus tropicalis	70.73	1.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence