iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036469

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02144560

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000029868.1	ENSFCAT00000029327.1	ENSFCAP00000019671.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.40e-16	58.0	153	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ ++LqhLCRl+I++c+g+     i++LPLP +LkdYL+++++q
   Q: 153  TKPLYTSAPPLQHLCRLTINKCTGT-----IWGLPLPTRLKDYLEEYKFQ 197
           678999*******************.....8***************9886 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MTLRCLESSG NGAEGTQSQW GTAGSAEEPS PEAARLAKAL RELGQTGWYW GSMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCTCAG GGTGCTTCGT CCTGGGGCCC CCGGCTGTGC GGGGTGTAAG ATAGAGGGGT 60
GCCAATTTGG GGATATCTCC TGTTCTTTCC TTTGCGATTT TTCTGCTTGT CCTTAACTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	97.98	9.00e-107	378.00
IUUC-Apl-003484	Anas platyrhynchos	79.74	2.00e-72	264.00
IUUC-Aca-004253	Anolis carolinensis	71.34	2.00e-71	261.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	2.40e-02	33.10
IUUC-Ame-011267	Astyanax mexicanus	62.28	6.00e-59	219.00
IUUC-Bta-013183	Bos taurus	97.47	6.00e-102	362.00
IUUC-Bra-017915	Brassica rapa	33.90	4.20e-02	32.00
IUUC-Cja-018862	Callithrix jacchus	96.97	6.00e-101	359.00
IUUC-Cfa-020226	Canis familiaris	95.94	1.00e-97	348.00
IUUC-Cpo-022414	Cavia porcellus	96.46	9.00e-105	372.00
IUUC-Csa-023758	Chlorocebus sabaeus	96.46	4.00e-105	373.00
IUUC-Cho-024471	Choloepus hoffmanni	86.84	4.00e-72	263.00
IUUC-Dre-028288	Danio rerio	56.48	2.00e-63	234.00
IUUC-Dno-029036	Dasypus novemcinctus	97.47	8.00e-107	379.00
IUUC-Dor-030447	Dipodomys ordii	98.68	2.00e-87	313.00
IUUC-Ete-033023	Echinops telfairi	92.93	1.00e-108	385.00
IUUC-Fal-036642	Ficedula albicollis	73.46	2.00e-70	257.00
IUUC-Gmo-039331	Gadus morhua	61.54	3.00e-35	139.00
IUUC-Gga-040809	Gallus gallus	76.73	9.00e-73	265.00
IUUC-Gac-041398	Gasterosteus aculeatus	60.12	2.00e-59	221.00
IUUC-Ggo-045341	Gorilla gorilla	97.47	5.00e-101	359.00
IUUC-Hsa-046557	Homo sapiens	96.97	1.00e-113	401.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	82.21	1.00e-92	332.00
IUUC-Lch-050160	Latimeria chalumnae	61.74	1.00e-49	188.00
IUUC-Loc-051825	Lepisosteus oculatus	56.25	2.00e-61	227.00
IUUC-Laf-053560	Loxodonta africana	94.95	2.00e-97	347.00
IUUC-Mcc-055890	Macaca mulatta	96.46	5.00e-100	356.00
IUUC-Meu-056218	Macropus eugenii	80.81	2.00e-96	344.00
IUUC-Mga-059755	Meleagris gallopavo	78.95	5.00e-71	259.00
IUUC-Mmr-061387	Microcebus murinus	98.99	1.00e-107	381.00
IUUC-Mdo-062383	Monodelphis domestica	82.32	1.00e-96	344.00
IUUC-Mmu-063443	Mus musculus	93.94	4.00e-101	360.00
IUUC-Mpu-066459	Mustela putorius furo	97.47	4.00e-101	360.00
IUUC-Mlu-068040	Myotis lucifugus	96.97	1.00e-106	378.00
IUUC-Nle-069016	Nomascus leucogenys	91.92	9.00e-98	348.00
IUUC-Opr-071087	Ochotona princeps	88.89	3.00e-103	367.00
IUUC-Ont-072340	Oreochromis niloticus	54.63	2.00e-59	221.00
IUUC-Oan-073443	Ornithorhynchus anatinus	78.28	3.00e-89	320.00
IUUC-Ocu-074539	Oryctolagus cuniculus	95.94	5.00e-100	356.00
IUUC-Ola-087004	Oryzias latipes	59.49	1.00e-54	205.00
IUUC-Oga-088438	Otolemur garnettii	96.46	4.00e-105	373.00
IUUC-Oar-089932	Ovis aries	97.47	1.00e-101	361.00
IUUC-Ptr-091037	Pan troglodytes	97.47	5.00e-101	359.00
IUUC-Pan-092767	Papio anubis	97.47	4.00e-101	360.00
IUUC-Psi-093099	Pelodiscus sinensis	76.73	1.00e-73	267.00
IUUC-Pma-094671	Petromyzon marinus	47.71	2.00e-35	142.00
IUUC-Pfo-097073	Poecilia formosa	50.00	3.00e-55	207.00
IUUC-Pab-098319	Pongo abelii	96.97	2.00e-106	377.00
IUUC-Pca-101117	Procavia capensis	94.44	1.00e-100	358.00
IUUC-Pva-102117	Pteropus vampyrus	96.46	1.00e-98	352.00
IUUC-Rno-105913	Rattus norvegicus	93.43	9.00e-101	359.00
IUUC-Sha-106500	Sarcophilus harrisii	82.23	3.00e-95	340.00
IUUC-Ssc-115252	Sus scrofa	97.98	6.00e-107	379.00
IUUC-Tgu-117524	Taeniopygia guttata	75.47	7.00e-70	255.00
IUUC-Tsy-119335	Tarsius syrichta	94.04	1.00e-84	304.00
IUUC-Tni-120263	Tetraodon nigroviridis	54.26	3.00e-56	211.00
IUUC-Tbe-127915	Tupaia belangeri	96.46	1.00e-98	351.00
IUUC-Ttr-128372	Tursiops truncatus	97.47	3.00e-106	377.00
IUUC-Vpa-130422	Vicugna pacos	100.00	8.00e-89	318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence