iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051825

Ensembl Protein ID

ENSLOCP00000019417.1

UniProt Accession

W5NFK8; W5NFK8_LEPOC

Genbank Protein ID

ENSLOCP00000019417

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01016211

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000015773.1	ENSLOCT00000019449.1	ENSLOCP00000019417.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.60e-13	49.8	150	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           ++++ ++ +SLqhLCR++I++++++     i+ LPLP++LkdYL  + 
   Q: 150  TKPVYTSIPSLQHLCRISINKATKR-----IQDLPLPNRLKDYLTDYI 192
           6778899******************.....8*************9875 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MTCHSSDSTE TIENERRSET ESRVVDSDQN RIAAAMRDLK KTGWYWGSLT ASEAKEILQD 60
TPEGTFLVRD SSQRDYLFTI SAKTSVGPTN LRIEYKDGKF KLDSVVLIKP KLKQFDSVVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCTCCTT CCGTGCTGAC AGGTAAGATT GTTTTCGTTC CAACGACACA GCACTGAGCT 60
GTACTAAAAA CGTCGTTTCT TTTTTTTTTC ATTCGTTTTA TTTATTCAAA TGAATCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	63.64	8.00e-60	222.00
IUUC-Apl-003484	Anas platyrhynchos	63.64	4.00e-57	213.00
IUUC-Aca-004253	Anolis carolinensis	57.58	4.00e-58	216.00
IUUC-Ame-011267	Astyanax mexicanus	74.40	1.00e-80	291.00
IUUC-Bta-013183	Bos taurus	64.52	5.00e-57	213.00
IUUC-Cja-018862	Callithrix jacchus	66.03	6.00e-58	216.00
IUUC-Cfa-020226	Canis familiaris	64.29	7.00e-56	209.00
IUUC-Cpo-022414	Cavia porcellus	65.16	4.00e-57	213.00
IUUC-Csa-023758	Chlorocebus sabaeus	64.74	3.00e-57	214.00
IUUC-Cho-024471	Choloepus hoffmanni	58.60	2.00e-47	181.00
IUUC-Dre-028288	Danio rerio	81.73	3.00e-94	337.00
IUUC-Dno-029036	Dasypus novemcinctus	56.25	5.00e-61	226.00
IUUC-Dor-030447	Dipodomys ordii	64.71	1.00e-55	208.00
IUUC-Ete-033023	Echinops telfairi	61.31	1.00e-60	225.00
IUUC-Eca-033422	Equus caballus	42.11	2.00e-40	159.00
IUUC-Eeu-034806	Erinaceus europaeus	40.67	2.00e-37	148.00
IUUC-Fca-036469	Felis catus	64.74	3.00e-57	214.00
IUUC-Fal-036642	Ficedula albicollis	62.82	2.00e-57	214.00
IUUC-Gmo-039331	Gadus morhua	77.05	2.00e-53	200.00
IUUC-Gga-040809	Gallus gallus	61.25	3.00e-58	216.00
IUUC-Gac-041398	Gasterosteus aculeatus	71.28	4.00e-82	296.00
IUUC-Ggo-045341	Gorilla gorilla	65.38	9.00e-58	216.00
IUUC-Hsa-046557	Homo sapiens	64.46	2.00e-61	228.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	64.74	1.00e-56	212.00
IUUC-Lch-050160	Latimeria chalumnae	66.10	5.00e-69	253.00
IUUC-Laf-053560	Loxodonta africana	65.81	3.00e-58	217.00
IUUC-Mcc-055890	Macaca mulatta	64.10	1.00e-56	212.00
IUUC-Meu-056218	Macropus eugenii	58.50	2.00e-63	234.00
IUUC-Mga-059755	Meleagris gallopavo	62.75	4.00e-56	210.00
IUUC-Mmr-061387	Microcebus murinus	64.74	2.00e-57	214.00
IUUC-Mdo-062383	Monodelphis domestica	59.11	7.00e-64	236.00
IUUC-Mmu-063443	Mus musculus	63.46	3.00e-56	211.00
IUUC-Mpu-066459	Mustela putorius furo	63.46	3.00e-56	210.00
IUUC-Mlu-068040	Myotis lucifugus	63.64	5.00e-60	223.00
IUUC-Nle-069016	Nomascus leucogenys	62.65	6.00e-58	216.00
IUUC-Opr-071087	Ochotona princeps	54.00	1.00e-58	219.00
IUUC-Ont-072340	Oreochromis niloticus	73.13	3.00e-86	310.00
IUUC-Oan-073443	Ornithorhynchus anatinus	59.38	2.00e-62	231.00
IUUC-Ocu-074539	Oryctolagus cuniculus	63.87	2.00e-55	208.00
IUUC-Ola-087004	Oryzias latipes	73.58	1.00e-66	244.00
IUUC-Oga-088438	Otolemur garnettii	64.10	4.00e-57	213.00
IUUC-Oar-089932	Ovis aries	64.52	9.00e-57	212.00
IUUC-Ptr-091037	Pan troglodytes	65.38	9.00e-58	216.00
IUUC-Pan-092767	Papio anubis	64.74	3.00e-57	214.00
IUUC-Psi-093099	Pelodiscus sinensis	63.35	9.00e-59	218.00
IUUC-Pma-094671	Petromyzon marinus	48.05	1.00e-38	152.00
IUUC-Pfo-097073	Poecilia formosa	67.35	3.00e-78	284.00
IUUC-Pab-098319	Pongo abelii	64.24	1.00e-60	225.00
IUUC-Pca-101117	Procavia capensis	65.81	3.00e-58	217.00
IUUC-Pva-102117	Pteropus vampyrus	65.16	1.00e-56	212.00
IUUC-Rno-105913	Rattus norvegicus	64.10	4.00e-57	214.00
IUUC-Sha-106500	Sarcophilus harrisii	64.88	4.00e-63	233.00
IUUC-Sar-113001	Sorex araneus	41.63	3.00e-40	158.00
IUUC-Ssc-115252	Sus scrofa	65.16	5.00e-57	213.00
IUUC-Tgu-117524	Taeniopygia guttata	61.88	1.00e-58	218.00
IUUC-Tru-118511	Takifugu rubripes	38.61	2.00e-24	105.00
IUUC-Tsy-119335	Tarsius syrichta	63.40	1.00e-54	205.00
IUUC-Tni-120263	Tetraodon nigroviridis	71.43	5.00e-77	280.00
IUUC-Tbe-127915	Tupaia belangeri	64.10	1.00e-56	212.00
IUUC-Ttr-128372	Tursiops truncatus	65.16	5.00e-57	213.00
IUUC-Vpa-130422	Vicugna pacos	64.71	1.00e-55	207.00
IUUC-Xtr-132941	Xenopus tropicalis	65.27	7.00e-64	236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence