iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000032930.5	ENSRNOT00000077201.1	ENSRNOP00000068752.1
ENSRNOG00000032930.5	ENSRNOT00000084596.1	ENSRNOP00000069587.1
ENSRNOG00000032930.5	ENSRNOT00000085912.1	ENSRNOP00000072863.1
ENSRNOG00000032930.5	ENSRNOT00000001019.6	ENSRNOP00000001019.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.70e-07	32.1	16	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++ +CgHvf+++C   +      s ++  CPlC+
   Q: 16   CSICLDYLRD-PVTIDCGHVFCRSCTSDI---RPISGNRPVCPLCK 57
           **********.999***********8555...333999999****6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAVSAPLRSL EEEVTCSICL DYLRDPVTID CGHVFCRSCT SDIRPISGNR PVCPLCKKPF 60
KKENIRPVWQ LASLVENIER LKVDNGKQPG ELAREPQDMK LCERHQEKLH YYCEDDGKLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGTGCGGC TGCTTGCTGA GGACCTACCC CCGGAACAGC TCCACGGAGA GGAGCGACCG 60
CCCGGAGCGC GGCGCGGTTG AGTGCGGCCT GCACTGGTGA GAGGCGGAGG ACAGCCGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002296	Ailuropoda melanoleuca	82.49	0.00e+00	650.00
IUUC-Bta-012463	Bos taurus	85.90	0.00e+00	660.00
IUUC-Cja-018768	Callithrix jacchus	85.90	0.00e+00	632.00
IUUC-Cfa-020619	Canis familiaris	79.70	1.00e-78	286.00
IUUC-Csa-024036	Chlorocebus sabaeus	86.17	0.00e+00	627.00
IUUC-Cho-024784	Choloepus hoffmanni	73.33	2.00e-62	232.00
IUUC-Dno-029308	Dasypus novemcinctus	72.96	6.00e-127	446.00
IUUC-Dor-030812	Dipodomys ordii	89.47	0.00e+00	666.00
IUUC-Ete-032424	Echinops telfairi	83.71	2.00e-87	316.00
IUUC-Eca-033331	Equus caballus	85.90	0.00e+00	636.00
IUUC-Fca-036166	Felis catus	82.71	0.00e+00	642.00
IUUC-Ggo-044614	Gorilla gorilla	85.90	2.00e-180	625.00
IUUC-Hsa-046497	Homo sapiens	86.17	0.00e+00	627.00
IUUC-Itr-047952	Ictidomys tridecemlineatus	90.24	0.00e+00	668.00
IUUC-Laf-054420	Loxodonta africana	82.18	0.00e+00	626.00
IUUC-Mcc-055692	Macaca mulatta	84.88	6.00e-176	610.00
IUUC-Meu-056070	Macropus eugenii	69.33	2.00e-142	499.00
IUUC-Mdo-062024	Monodelphis domestica	69.60	1.00e-147	516.00
IUUC-Mmu-063867	Mus musculus	97.88	0.00e+00	734.00
IUUC-Mpu-066285	Mustela putorius furo	81.91	6.00e-177	613.00
IUUC-Mlu-066931	Myotis lucifugus	77.72	1.00e-168	586.00
IUUC-Nle-069433	Nomascus leucogenys	86.17	0.00e+00	627.00
IUUC-Opr-070804	Ochotona princeps	85.11	0.00e+00	658.00
IUUC-Ocu-074288	Oryctolagus cuniculus	86.44	1.00e-179	622.00
IUUC-Oga-088525	Otolemur garnettii	85.37	0.00e+00	662.00
IUUC-Oar-089671	Ovis aries	74.40	1.00e-154	539.00
IUUC-Ptr-090593	Pan troglodytes	86.17	0.00e+00	627.00
IUUC-Pan-092128	Papio anubis	86.17	0.00e+00	627.00
IUUC-Ppa-095647	Physcomitrella patens	28.04	1.00e-07	50.80
IUUC-Pab-098693	Pongo abelii	86.17	0.00e+00	627.00
IUUC-Pva-102332	Pteropus vampyrus	84.40	0.00e+00	811.00
IUUC-Sha-107080	Sarcophilus harrisii	69.74	3.00e-146	511.00
IUUC-Smo-109430	Selaginella moellendorffii	41.67	5.00e-09	55.10
IUUC-Sar-112969	Sorex araneus	69.27	0.00e+00	640.00
IUUC-Ssc-115426	Sus scrofa	84.84	0.00e+00	658.00
IUUC-Tsy-118963	Tarsius syrichta	85.97	4.00e-168	584.00
IUUC-Tbe-127732	Tupaia belangeri	85.07	0.00e+00	658.00
IUUC-Ttr-128856	Tursiops truncatus	91.01	7.00e-96	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence