iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090017

Ensembl Protein ID

ENSOARP00000022515.1

UniProt Accession

W5QIG3; W5QIG3_SHEEP

Genbank Protein ID

ENSOARP00000022515

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01103530

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020950.1	ENSOART00000022825.1	ENSOARP00000022515.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-42	142.2	194	233
UBD/Beta-Prp	1.20e-53	182.4	189	395

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllks 38
           Ht+  ++++f  sd   ++++s+Dgt+ +WD+ +g ll+s
   Q: 194  HTNYLSACSFtnSDmQQILTASGDGTCALWDVESGQLLQS 233
           999999*****988999******************99986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
           +s+  h++  +a++f +++   ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++ 
   Q: 189  KSVAMHTNYLSACSFTNSDMqQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ- 276
           5678899999999998876559**************************************9778************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l 
   Q: 277  AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF 365
           ********************************************5333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsiriW 249
           gh++ v+ +r+sp+++ + sgs D ++r+W
   Q: 366  GHENRVSTLRVSPDGTAFCSGSWDHTLRVW 395
           ****************************** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

NMDQTFLVNV FGSCDRCFKQ RALRPVFKKS EQLNYCSLCA EIISWAGCHP QTKLASVKAE 60
THVKKGKRKK KFFKLEFSEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATATGGATC AGACCTTTTT AGTTAATGTA TTTGGCTCCT GTGACAGATG CTTCAAACAA 60
CGGGCTCTGA GACCAGTTTT CAAGAAATCT GAACAGCTCA ACTACTGTTC ACTATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	89.09	0.00e+00	725.00
IUUC-Apl-003399	Anas platyrhynchos	98.09	0.00e+00	642.00
IUUC-Aca-004861	Anolis carolinensis	87.06	0.00e+00	709.00
IUUC-Ame-011851	Astyanax mexicanus	88.44	0.00e+00	639.00
IUUC-Bta-012438	Bos taurus	94.00	0.00e+00	668.00
IUUC-Cel-018408	Caenorhabditis elegans	65.93	4.00e-129	454.00
IUUC-Cja-019086	Callithrix jacchus	92.35	0.00e+00	739.00
IUUC-Cfa-021255	Canis familiaris	91.58	0.00e+00	717.00
IUUC-Cpo-021398	Cavia porcellus	91.37	0.00e+00	742.00
IUUC-Csa-023776	Chlorocebus sabaeus	93.97	0.00e+00	666.00
IUUC-Cin-025305	Ciona intestinalis	55.62	3.00e-122	431.00
IUUC-Csv-026058	Ciona savignyi	61.18	2.00e-120	425.00
IUUC-Dre-028432	Danio rerio	80.46	0.00e+00	647.00
IUUC-Dno-029958	Dasypus novemcinctus	81.31	5.00e-134	470.00
IUUC-Dor-031013	Dipodomys ordii	98.83	4.00e-151	527.00
IUUC-Dme-031889	Drosophila melanogaster	65.41	7.00e-138	483.00
IUUC-Eca-033977	Equus caballus	89.85	0.00e+00	726.00
IUUC-Eeu-035079	Erinaceus europaeus	91.09	0.00e+00	729.00
IUUC-Fca-035693	Felis catus	89.90	0.00e+00	725.00
IUUC-Fal-037345	Ficedula albicollis	92.29	0.00e+00	662.00
IUUC-Gmo-039222	Gadus morhua	93.40	0.00e+00	632.00
IUUC-Gga-040320	Gallus gallus	92.57	0.00e+00	663.00
IUUC-Gac-042644	Gasterosteus aculeatus	87.93	0.00e+00	639.00
IUUC-Ggo-044489	Gorilla gorilla	91.14	0.00e+00	732.00
IUUC-Hsa-046434	Homo sapiens	92.39	0.00e+00	744.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.65	8.00e-174	602.00
IUUC-Loc-052790	Lepisosteus oculatus	85.42	0.00e+00	682.00
IUUC-Laf-054255	Loxodonta africana	91.07	0.00e+00	730.00
IUUC-Mcc-055610	Macaca mulatta	91.84	0.00e+00	735.00
IUUC-Meu-056819	Macropus eugenii	85.17	0.00e+00	676.00
IUUC-Mga-059740	Meleagris gallopavo	85.50	0.00e+00	694.00
IUUC-Mmr-061221	Microcebus murinus	92.13	0.00e+00	741.00
IUUC-Mdo-062619	Monodelphis domestica	92.57	0.00e+00	666.00
IUUC-Mmu-064266	Mus musculus	92.39	0.00e+00	745.00
IUUC-Mpu-065766	Mustela putorius furo	98.68	3.00e-179	620.00
IUUC-Mlu-067221	Myotis lucifugus	88.89	0.00e+00	725.00
IUUC-Nle-069515	Nomascus leucogenys	99.05	0.00e+00	652.00
IUUC-Opr-070195	Ochotona princeps	83.80	0.00e+00	659.00
IUUC-Ont-071535	Oreochromis niloticus	75.38	1.00e-165	575.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	5.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.01	1.00e-179	621.00
IUUC-Ola-086578	Oryzias latipes	94.32	0.00e+00	632.00
IUUC-Oga-089090	Otolemur garnettii	92.17	0.00e+00	741.00
IUUC-Ptr-091280	Pan troglodytes	88.83	0.00e+00	710.00
IUUC-Pan-092198	Papio anubis	99.05	0.00e+00	652.00
IUUC-Psi-093030	Pelodiscus sinensis	84.29	0.00e+00	695.00
IUUC-Pma-094140	Petromyzon marinus	73.68	2.00e-86	311.00
IUUC-Pfo-097182	Poecilia formosa	94.03	0.00e+00	635.00
IUUC-Pab-098157	Pongo abelii	93.71	0.00e+00	668.00
IUUC-Pca-100988	Procavia capensis	70.81	2.00e-150	525.00
IUUC-Pva-102232	Pteropus vampyrus	99.63	1.00e-159	555.00
IUUC-Rno-105526	Rattus norvegicus	89.77	0.00e+00	629.00
IUUC-Sha-106754	Sarcophilus harrisii	90.10	0.00e+00	716.00
IUUC-Ssc-115390	Sus scrofa	92.39	0.00e+00	751.00
IUUC-Tgu-117377	Taeniopygia guttata	86.58	0.00e+00	696.00
IUUC-Tru-117938	Takifugu rubripes	94.03	0.00e+00	633.00
IUUC-Tsy-119392	Tarsius syrichta	79.44	4.00e-176	610.00
IUUC-Tni-119834	Tetraodon nigroviridis	69.29	1.00e-157	549.00
IUUC-Tbe-127469	Tupaia belangeri	89.92	0.00e+00	670.00
IUUC-Ttr-128252	Tursiops truncatus	88.86	0.00e+00	701.00
IUUC-Vpa-130173	Vicugna pacos	80.00	1.00e-153	535.00
IUUC-Xtr-131803	Xenopus tropicalis	85.79	0.00e+00	691.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence