iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000018220.2	ENSCJAT00000035669.2	ENSCJAP00000033763.2
ENSCJAG00000018220.2	ENSCJAT00000035655.1	ENSCJAP00000033750.1
ENSCJAG00000018220.2	ENSCJAT00000060118.1	ENSCJAP00000042345.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	6.60e-55	186.7	220	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e++++leC+h++Ck+Clk+y+e++i++gqv++++cp+++c++ +++ ++ke lve+el++ry++lll+++++ +a++ +
   Q: 220  CNICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCSSVATPGQVKE-LVEAELFARYDRLLLQSTLDLMADVVY 308
           **************************************************************.7************************** PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+p+C+l+v++e+     ++  c++c+++fC+ C+ ++H  + Ck ++ekl++ ++e+                        ee es+e
   Q: 309  CPRPCCQLPVMQEPG---CTMGiCSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYlqadepnkrlleqrygkrviqkalEELESQE 395
           *************95...33337**********************************99******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C ++iek +gCn+mtC+ C+++fCw+C
   Q: 396  WLEKNSKNCPCCGTPIEKLDGCNKMTCTGCMQYFCWIC 433
           ************************************** PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

LTSKDREAQE DELLALASIY DGDEFRKAES VQGGETRIYL DLPQNFKIFV SGNSNECLQN 60
SGFEYTICFL PPLVLNFELP PDYPSSSPPS FTLSGKWLSP TQLSALCKHL DNLWEEHRGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTGACAGC TACCGAGAAC GGAAGAGGCG GCGCGCCGGT TCAGCGGGGC GTCCCTAGGC 60
CTGGTCGGCT GGGGTCGGTG AGTGGGCCCC GGGCAAGGGC GGAGGGCGGA ACTTTGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0060765--P:regulation of androgen receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	29.85	4.00e-51	195.00
IUUC-Aml-001458	Ailuropoda melanoleuca	95.17	0.00e+00	907.00
IUUC-Atr-002560	Amborella trichopoda	30.94	8.00e-46	178.00
IUUC-Apl-003680	Anas platyrhynchos	81.22	0.00e+00	772.00
IUUC-Aca-005000	Anolis carolinensis	72.02	0.00e+00	666.00
IUUC-Aly-006288	Arabidopsis lyrata	31.39	3.00e-54	206.00
IUUC-Ath-006719	Arabidopsis thaliana	31.17	1.00e-53	204.00
IUUC-Acl-008213	Aspergillus clavatus	25.05	2.00e-30	127.00
IUUC-Afl-008433	Aspergillus flavus	25.00	8.00e-31	128.00
IUUC-Afu-008772	Aspergillus fumigatus	25.49	1.00e-32	134.00
IUUC-Ani-009249	Aspergillus nidulans	25.65	1.00e-32	134.00
IUUC-Ang-009757	Aspergillus niger	28.23	4.00e-37	149.00
IUUC-Aor-009963	Aspergillus oryzae	25.00	2.00e-30	127.00
IUUC-Ate-010460	Aspergillus terreus	25.11	1.00e-31	131.00
IUUC-Ame-011312	Astyanax mexicanus	59.26	1.00e-146	512.00
IUUC-Bgr-012052	Blumeria graminis	23.02	8.00e-29	122.00
IUUC-Bta-013529	Bos taurus	94.73	0.00e+00	910.00
IUUC-Bci-013729	Botrytis cinerea	25.16	7.00e-27	115.00
IUUC-Bdi-014940	Brachypodium distachyon	31.75	7.00e-49	188.00
IUUC-Bra-016998	Brassica rapa	30.27	1.00e-50	194.00
IUUC-Cel-018547	Caenorhabditis elegans	30.72	8.00e-50	191.00
IUUC-Cfa-020403	Canis familiaris	94.73	0.00e+00	911.00
IUUC-Cpo-022229	Cavia porcellus	89.50	0.00e+00	850.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	34.88	3.00e-30	124.00
IUUC-Csa-024115	Chlorocebus sabaeus	97.05	0.00e+00	928.00
IUUC-Cho-024911	Choloepus hoffmanni	94.94	0.00e+00	911.00
IUUC-Cin-025578	Ciona intestinalis	41.79	1.00e-97	350.00
IUUC-Csv-026355	Ciona savignyi	40.48	8.00e-83	300.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	24.33	5.00e-25	109.00
IUUC-Cne-026782	Cryptococcus neoformans	25.74	6.00e-30	125.00
IUUC-Dre-027380	Danio rerio	56.47	1.00e-152	532.00
IUUC-Dno-029640	Dasypus novemcinctus	94.32	0.00e+00	901.00
IUUC-Dor-030681	Dipodomys ordii	93.46	0.00e+00	896.00
IUUC-Dse-031208	Dothistroma septosporum	25.08	4.00e-31	129.00
IUUC-Ete-033122	Echinops telfairi	60.68	2.00e-134	471.00
IUUC-Eca-033755	Equus caballus	92.93	0.00e+00	878.00
IUUC-Eeu-035034	Erinaceus europaeus	96.58	3.00e-72	265.00
IUUC-Fca-036461	Felis catus	94.94	0.00e+00	911.00
IUUC-Fal-037516	Ficedula albicollis	80.42	0.00e+00	771.00
IUUC-Fso-038307	Fusarium solani	24.21	2.00e-24	107.00
IUUC-Gmo-039563	Gadus morhua	57.49	5.00e-148	517.00
IUUC-Ggr-039920	Gaeumannomyces graminis	24.60	7.00e-23	102.00
IUUC-Gga-040331	Gallus gallus	80.25	0.00e+00	752.00
IUUC-Gac-042164	Gasterosteus aculeatus	59.03	1.00e-158	553.00
IUUC-Gma-044080	Glycine max	32.50	3.00e-57	216.00
IUUC-Ggo-045257	Gorilla gorilla	97.05	0.00e+00	931.00
IUUC-Hsa-046887	Homo sapiens	97.39	0.00e+00	903.00
IUUC-Hvu-047317	Hordeum vulgare	29.75	3.00e-49	189.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	94.09	0.00e+00	905.00
IUUC-Lch-050155	Latimeria chalumnae	63.69	7.00e-164	570.00
IUUC-Lpe-051669	Leersia perrieri	30.65	4.00e-39	156.00
IUUC-Loc-051779	Lepisosteus oculatus	60.50	4.00e-155	541.00
IUUC-Lma-052969	Leptosphaeria maculans	24.34	1.00e-29	124.00
IUUC-Laf-053488	Loxodonta africana	91.77	0.00e+00	879.00
IUUC-Mcc-054701	Macaca mulatta	97.83	0.00e+00	905.00
IUUC-Meu-056577	Macropus eugenii	82.55	1.00e-126	446.00
IUUC-Mor-057157	Magnaporthe oryzae	25.29	2.00e-27	117.00
IUUC-Mpo-057518	Magnaporthe poae	23.49	1.00e-26	114.00
IUUC-Mtr-058125	Medicago truncatula	29.74	4.00e-45	176.00
IUUC-Mga-059906	Meleagris gallopavo	79.83	0.00e+00	748.00
IUUC-Mvi-060374	Microbotryum violaceum	31.71	5.00e-33	135.00
IUUC-Mmr-061786	Microcebus murinus	95.57	0.00e+00	915.00
IUUC-Mdo-062453	Monodelphis domestica	89.47	0.00e+00	830.00
IUUC-Mmu-063521	Mus musculus	89.38	0.00e+00	803.00
IUUC-Mac-065119	Musa acuminata	30.37	1.00e-40	160.00
IUUC-Mpu-066274	Mustela putorius furo	94.51	0.00e+00	907.00
IUUC-Mlu-067202	Myotis lucifugus	91.96	0.00e+00	842.00
IUUC-Nfi-068564	Neosartorya fischeri	24.62	2.00e-31	130.00
IUUC-Ncr-068823	Neurospora crassa	24.34	1.00e-30	128.00
IUUC-Nle-068987	Nomascus leucogenys	97.61	0.00e+00	906.00
IUUC-Opr-070453	Ochotona princeps	91.56	0.00e+00	876.00
IUUC-Ont-072611	Oreochromis niloticus	57.56	1.00e-157	549.00
IUUC-Oan-073738	Ornithorhynchus anatinus	81.09	0.00e+00	742.00
IUUC-Ocu-074396	Oryctolagus cuniculus	92.83	0.00e+00	890.00
IUUC-Oba-075472	Oryza barthii	31.59	9.00e-43	168.00
IUUC-Obr-076277	Oryza brachyantha	31.59	8.00e-46	178.00
IUUC-Ogl-077046	Oryza glaberrima	31.28	2.00e-41	163.00
IUUC-Ogu-078634	Oryza glumaepatula	31.59	4.00e-43	169.00
IUUC-Oin-080080	Oryza indica	29.85	2.00e-44	173.00
IUUC-Olo-080828	Oryza longistaminata	29.00	8.00e-42	166.00
IUUC-Ome-081387	Oryza meridionalis	29.84	6.00e-47	182.00
IUUC-Oni-082934	Oryza nivara	31.59	4.00e-43	169.00
IUUC-Opu-083719	Oryza punctata	28.81	6.00e-41	161.00
IUUC-Oru-084518	Oryza rufipogon	31.59	4.00e-43	169.00
IUUC-Ola-087312	Oryzias latipes	58.88	4.00e-156	544.00
IUUC-Olu-087661	Ostreococcus lucimarinus	28.85	1.00e-46	181.00
IUUC-Oga-089129	Otolemur garnettii	95.56	0.00e+00	911.00
IUUC-Oar-089839	Ovis aries	94.51	0.00e+00	909.00
IUUC-Ptr-091626	Pan troglodytes	97.61	0.00e+00	904.00
IUUC-Pan-092798	Papio anubis	97.83	0.00e+00	905.00
IUUC-Psi-093253	Pelodiscus sinensis	81.40	0.00e+00	784.00
IUUC-Pma-094512	Petromyzon marinus	54.31	5.00e-142	497.00
IUUC-Pno-094937	Phaeosphaeria nodorum	23.25	2.00e-28	120.00
IUUC-Ppa-095211	Physcomitrella patens	30.50	6.00e-54	205.00
IUUC-Pfo-097049	Poecilia formosa	52.77	4.00e-137	481.00
IUUC-Pab-097911	Pongo abelii	97.39	0.00e+00	902.00
IUUC-Pop-099841	Populus trichocarpa	30.84	4.00e-49	189.00
IUUC-Pca-100814	Procavia capensis	73.09	0.00e+00	652.00
IUUC-Ppe-101972	Prunus persica	30.04	1.00e-49	191.00
IUUC-Pva-103038	Pteropus vampyrus	94.30	0.00e+00	902.00
IUUC-Pgr-103277	Puccinia graminis	33.97	1.00e-38	154.00
IUUC-Ptt-103855	Puccinia triticina	31.60	4.00e-36	145.00
IUUC-Pte-104113	Pyrenophora teres	22.64	2.00e-25	110.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	25.28	2.00e-26	113.00
IUUC-Rno-106003	Rattus norvegicus	90.48	0.00e+00	828.00
IUUC-Sce-106287	Saccharomyces cerevisiae	27.84	8.00e-24	104.00
IUUC-Sha-106652	Sarcophilus harrisii	89.15	0.00e+00	838.00
IUUC-Spo-108167	Schizosaccharomyces pombe	31.65	6.00e-53	201.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	25.00	1.00e-09	58.50
IUUC-Smo-109393	Selaginella moellendorffii	31.26	2.00e-48	186.00
IUUC-Sit-110529	Setaria italica	33.93	2.00e-42	166.00
IUUC-Sly-111829	Solanum lycopersicum	29.71	2.00e-52	200.00
IUUC-Stu-112811	Solanum tuberosum	29.93	6.00e-53	202.00
IUUC-Sar-113259	Sorex araneus	89.57	4.00e-138	484.00
IUUC-Sbi-114591	Sorghum bicolor	32.53	5.00e-36	145.00
IUUC-Sre-115227	Sporisorium reilianum	29.32	5.00e-38	152.00
IUUC-Ssc-115293	Sus scrofa	93.04	0.00e+00	894.00
IUUC-Tgu-117335	Taeniopygia guttata	81.14	0.00e+00	769.00
IUUC-Tru-118458	Takifugu rubripes	56.99	1.00e-154	539.00
IUUC-Tsy-119475	Tarsius syrichta	86.71	0.00e+00	803.00
IUUC-Tni-119827	Tetraodon nigroviridis	56.26	4.00e-152	531.00
IUUC-Tca-121023	Theobroma cacao	32.16	6.00e-51	195.00
IUUC-Tre-121965	Trichoderma reesei	24.12	2.00e-29	123.00
IUUC-Tvi-122564	Trichoderma virens	21.54	8.00e-27	115.00
IUUC-Tae-124793	Triticum aestivum	33.19	1.00e-39	158.00
IUUC-Tur-126258	Triticum urartu	30.12	8.00e-45	175.00
IUUC-Tbe-127227	Tupaia belangeri	71.43	1.00e-75	276.00
IUUC-Ttr-128984	Tursiops truncatus	72.57	0.00e+00	626.00
IUUC-Uma-129565	Ustilago maydis	27.69	4.00e-36	146.00
IUUC-Vpa-130301	Vicugna pacos	95.15	0.00e+00	915.00
IUUC-Vvi-131244	Vitis vinifera	31.09	3.00e-52	199.00
IUUC-Xtr-132880	Xenopus tropicalis	59.54	2.00e-164	572.00
IUUC-Xma-134055	Xiphophorus maculatus	57.98	2.00e-157	548.00
IUUC-Yli-134342	Yarrowia lipolytica	29.83	2.00e-43	170.00
IUUC-Zma-135021	Zea mays	32.78	4.00e-38	152.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence