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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018354
Ensembl Protein ID T12D8.1
UniProt Accession G5EGI1; G5EGI1_CAEEL
Genbank Protein ID CAB03348.3
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID BX284603
Gene Name set-16; CELE_T12D8.1; T12D8.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00011729 T12D8.1 T12D8.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndex
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.40e-16 60.7 427 479
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedek.slveCekCrewfHpaClkls..veeelpnsekwiCpkCrs 53
           +ClvCg+ g++ + s+v C++C + +H  C+ l    ++ + ++  w C +C+ 
   Q: 427  MCLVCGSIGKGPEgSMVACSNCAQTYHTYCVTLHdkLNSAVVGRG-WRCLDCTV 479
           8**********999*******************966666666665.******86 PP
   
Organism Caenorhabditis elegans
Protein Sequence
(Fasta)
MICIECGGTA FNNTELCENC MDVNRSGTMS LDMARQCDMS SSCGSCQRMI TADSRQCTTC 60
RKSYHLSCDS SDVSSLNNFV CISCRRRSQM LPDDVMLSAS ARPSRGQDAP LSPFSDPSVP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018354|E3,PHD|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTCAAATTC GTATCGATTG AAGCTTCAAA AATCGAGAAA GCCGACTATA TGAAGTCCAA 60
AAGATGATTG TAAGTGTTCA CCGTTCAAAA TTTTAACTAT ACATCAAAAT TAAAATTCCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018354|E3,PHD|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0051568--P:histone H3-K4 methylation
GO:0040028--P:regulation of vulval development
KEGG cel:CELE_T12D8.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002314 Ailuropoda melanoleuca 35.33 1.00e-100 362.00
IUUC-Atr-002455 Amborella trichopoda 41.29 4.00e-30 125.00
IUUC-Apl-003311 Anas platyrhynchos 35.33 3.00e-97 350.00
IUUC-Aca-005364 Anolis carolinensis 36.72 2.00e-93 338.00
IUUC-Aly-006293 Arabidopsis lyrata 48.61 3.00e-35 142.00
IUUC-Ath-006690 Arabidopsis thaliana 44.51 1.00e-35 144.00
IUUC-Ani-009406 Aspergillus nidulans 54.17 7.00e-10 57.80
IUUC-Ame-010612 Astyanax mexicanus 37.19 4.00e-63 237.00
IUUC-Bta-012322 Bos taurus 34.82 3.00e-95 344.00
IUUC-Bdi-014882 Brachypodium distachyon 27.66 2.00e-19 89.40
IUUC-Bol-016540 Brassica oleracea 45.78 1.00e-35 144.00
IUUC-Bra-017732 Brassica rapa 29.65 9.00e-24 103.00
IUUC-Cja-019983 Callithrix jacchus 35.33 6.00e-101 363.00
IUUC-Cfa-020903 Canis familiaris 35.33 2.00e-100 361.00
IUUC-Cpo-021732 Cavia porcellus 35.16 2.00e-100 361.00
IUUC-Cre-022891 Chlamydomonas reinhardtii 46.56 2.00e-30 127.00
IUUC-Csa-023083 Chlorocebus sabaeus 35.16 9.00e-101 362.00
IUUC-Cho-024652 Choloepus hoffmanni 43.14 1.00e-33 139.00
IUUC-Cin-025724 Ciona intestinalis 47.06 1.00e-36 147.00
IUUC-Csv-026268 Ciona savignyi 46.41 4.00e-35 142.00
IUUC-Cme-027224 Cyanidioschyzon merolae 36.71 2.00e-12 66.60
IUUC-Dre-028110 Danio rerio 36.36 2.00e-108 387.00
IUUC-Dno-029932 Dasypus novemcinctus 36.94 1.00e-98 355.00
IUUC-Dor-030569 Dipodomys ordii 32.97 2.00e-84 308.00
IUUC-Dme-031590 Drosophila melanogaster 37.88 3.00e-46 179.00
IUUC-Ete-032572 Echinops telfairi 36.26 3.00e-86 314.00
IUUC-Eca-033945 Equus caballus 45.77 6.00e-58 219.00
IUUC-Eeu-034848 Erinaceus europaeus 42.08 4.00e-50 194.00
IUUC-Fca-035922 Felis catus 35.33 6.00e-102 366.00
IUUC-Fal-037179 Ficedula albicollis 36.08 2.00e-91 332.00
IUUC-Gmo-038719 Gadus morhua 35.99 7.00e-62 233.00
IUUC-Gga-040815 Gallus gallus 38.37 2.00e-46 182.00
IUUC-Gac-042436 Gasterosteus aculeatus 36.56 3.00e-65 244.00
IUUC-Gma-043554 Glycine max 42.22 1.00e-35 143.00
IUUC-Ggo-044812 Gorilla gorilla 35.16 1.00e-100 362.00
IUUC-Hsa-046595 Homo sapiens 34.99 4.00e-96 347.00
IUUC-Hvu-047762 Hordeum vulgare 28.05 8.00e-12 63.90
IUUC-Itr-048303 Ictidomys tridecemlineatus 35.33 2.00e-100 362.00
IUUC-Lch-050086 Latimeria chalumnae 35.68 3.00e-99 357.00
IUUC-Lpe-051476 Leersia perrieri 26.67 3.00e-15 75.90
IUUC-Loc-051979 Lepisosteus oculatus 36.17 2.00e-65 245.00
IUUC-Laf-054377 Loxodonta africana 36.94 2.00e-99 358.00
IUUC-Mcc-054868 Macaca mulatta 35.16 9.00e-101 362.00
IUUC-Meu-055992 Macropus eugenii 36.90 2.00e-99 358.00
IUUC-Mor-056964 Magnaporthe oryzae 54.35 3.00e-10 58.90
IUUC-Mtr-058327 Medicago truncatula 43.21 2.00e-34 140.00
IUUC-Mga-059541 Meleagris gallopavo 30.67 2.00e-65 245.00
IUUC-Mmr-061092 Microcebus murinus 35.16 2.00e-100 361.00
IUUC-Mdo-062610 Monodelphis domestica 44.28 2.00e-53 204.00
IUUC-Mmu-063903 Mus musculus 37.11 3.00e-99 357.00
IUUC-Mac-064935 Musa acuminata 29.11 5.00e-21 95.50
IUUC-Mpu-066366 Mustela putorius furo 35.16 2.00e-96 348.00
IUUC-Mlu-068201 Myotis lucifugus 35.51 1.00e-100 362.00
IUUC-Nfi-068246 Neosartorya fischeri 45.61 7.00e-09 54.30
IUUC-Nle-069232 Nomascus leucogenys 35.16 4.00e-100 360.00
IUUC-Opr-070304 Ochotona princeps 43.43 4.00e-52 201.00
IUUC-Ont-071881 Oreochromis niloticus 37.81 4.00e-67 250.00
IUUC-Oan-072945 Ornithorhynchus anatinus 35.51 1.00e-100 362.00
IUUC-Ocu-074920 Oryctolagus cuniculus 35.16 1.00e-100 362.00
IUUC-Oba-075647 Oryza barthii 41.92 7.00e-33 134.00
IUUC-Obr-076458 Oryza brachyantha 27.60 9.00e-19 87.40
IUUC-Ogl-077851 Oryza glaberrima 27.66 6.00e-19 88.20
IUUC-Ogu-078706 Oryza glumaepatula 28.05 7.00e-19 88.20
IUUC-Oin-079802 Oryza indica 26.34 6.00e-14 71.20
IUUC-Olo-080577 Oryza longistaminata 45.83 2.00e-32 132.00
IUUC-Ome-081214 Oryza meridionalis 41.92 2.00e-32 133.00
IUUC-Oni-083000 Oryza nivara 41.92 7.00e-33 134.00
IUUC-Opu-083842 Oryza punctata 41.92 1.00e-32 134.00
IUUC-Oru-084361 Oryza rufipogon 42.59 8.00e-33 134.00
IUUC-Osa-085421 Oryza sativa 28.05 1.00e-18 87.00
IUUC-Ola-086384 Oryzias latipes 37.77 4.00e-67 250.00
IUUC-Olu-087718 Ostreococcus lucimarinus 36.65 2.00e-25 110.00
IUUC-Oga-088450 Otolemur garnettii 37.11 1.00e-99 358.00
IUUC-Oar-089975 Ovis aries 37.11 2.00e-99 358.00
IUUC-Ptr-091527 Pan troglodytes 35.16 6.00e-101 363.00
IUUC-Pan-092102 Papio anubis 35.16 1.00e-100 362.00
IUUC-Psi-094059 Pelodiscus sinensis 44.16 2.00e-35 145.00
IUUC-Pma-094252 Petromyzon marinus 40.79 9.00e-50 192.00
IUUC-Ppa-095221 Physcomitrella patens 30.09 2.00e-24 106.00
IUUC-Pfo-096835 Poecilia formosa 37.78 1.00e-105 378.00
IUUC-Pab-098241 Pongo abelii 35.38 7.00e-64 239.00
IUUC-Pop-099620 Populus trichocarpa 27.62 2.00e-20 93.60
IUUC-Pca-100103 Procavia capensis 35.16 1.00e-99 358.00
IUUC-Ppe-101920 Prunus persica 29.91 9.00e-22 97.80
IUUC-Pva-102898 Pteropus vampyrus 36.60 9.00e-95 342.00
IUUC-Rno-105660 Rattus norvegicus 35.23 2.00e-86 315.00
IUUC-Sha-106550 Sarcophilus harrisii 35.68 1.00e-100 362.00
IUUC-Smo-109164 Selaginella moellendorffii 41.24 1.00e-29 124.00
IUUC-Sit-110552 Setaria italica 28.09 1.00e-19 90.50
IUUC-Sly-111158 Solanum lycopersicum 47.92 4.00e-35 142.00
IUUC-Stu-112529 Solanum tuberosum 48.61 3.00e-35 142.00
IUUC-Sar-113183 Sorex araneus 39.01 5.00e-48 187.00
IUUC-Sbi-114254 Sorghum bicolor 25.45 3.00e-09 55.80
IUUC-Ssc-115678 Sus scrofa 36.57 4.00e-96 347.00
IUUC-Tgu-116677 Taeniopygia guttata 35.33 2.00e-97 351.00
IUUC-Tru-118141 Takifugu rubripes 38.27 4.00e-113 403.00
IUUC-Tsy-118932 Tarsius syrichta 34.99 5.00e-100 360.00
IUUC-Tni-119970 Tetraodon nigroviridis 28.87 1.00e-75 279.00
IUUC-Tca-121624 Theobroma cacao 28.32 4.00e-22 99.00
IUUC-Tre-122041 Trichoderma reesei 37.97 2.00e-05 44.30
IUUC-Tae-125629 Triticum aestivum 29.23 2.00e-12 65.90
IUUC-Tme-127087 Tuber melanosporum 51.11 4.00e-11 63.20
IUUC-Tbe-127950 Tupaia belangeri 44.44 4.00e-36 147.00
IUUC-Ttr-129051 Tursiops truncatus 30.87 5.00e-77 283.00
IUUC-Vpa-130660 Vicugna pacos 41.46 2.00e-27 119.00
IUUC-Vvi-130873 Vitis vinifera 41.14 3.00e-35 142.00
IUUC-Xtr-132455 Xenopus tropicalis 35.06 5.00e-92 333.00
IUUC-Xma-133751 Xiphophorus maculatus 37.61 3.00e-104 374.00
Created Date 25-Jun-2017

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