iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.00e-06	26.9	23	60
UBD/SH3	4.10e-16	59.1	241	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           ++l+ l + GF++++al+aL+a+  +++e+A+++L+ +
   Q: 23   SLLDPLLALGFPTHTALKALAATgMKTAEEAADWLHGH 60
           78999******************************865 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++++l++y++qn deL l  Gd ++v   ++ee +egW  g ++ +g+rG++Pen++e+++
   Q: 241  QTLKALFQYKPQNADELMLSPGDYIFVDptQQEEASEGWAIGISHRTGCRGFLPENYTERAN 302
           5789***********************9999****************************997 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAAGETQLYA KVSNKLKGRS TSSLLDPLLA LGFPTHTALK ALAATGMKTA EEAADWLHGH 60
CSDPSLDDPI PQEYALFLCP TGPLLEKLQE FWRESRRQCA KNKAHEVFPH VTLCDFFTCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATCTAATCC TTGCAGTGAG CAGACGCCTC GTGTACGGCA AGCAGGAAGG CATGGCTGCC 60
GGGGAGACAC AGCTCTATGC CAAGGTCTCC AACAAGCTCA AGGGCCGCAG CACCTCCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0050860--P:negative regulation of T cell receptor signaling pathway
GO:0001817--P:regulation of cytokine production

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001941	Ailuropoda melanoleuca	85.19	0.00e+00	1130.00
IUUC-Atr-003098	Amborella trichopoda	28.43	7.00e-06	45.10
IUUC-Apl-003555	Anas platyrhynchos	66.02	0.00e+00	896.00
IUUC-Aca-004356	Anolis carolinensis	61.41	0.00e+00	688.00
IUUC-Bgr-012101	Blumeria graminis	28.71	2.00e-12	66.20
IUUC-Bta-012798	Bos taurus	80.80	0.00e+00	1068.00
IUUC-Bol-015778	Brassica oleracea	29.03	7.00e-05	41.20
IUUC-Cja-018791	Callithrix jacchus	71.00	0.00e+00	912.00
IUUC-Cfa-020366	Canis familiaris	83.90	0.00e+00	1090.00
IUUC-Cpo-022474	Cavia porcellus	81.03	0.00e+00	1025.00
IUUC-Csa-023131	Chlorocebus sabaeus	83.17	0.00e+00	1085.00
IUUC-Cho-024803	Choloepus hoffmanni	66.47	9.00e-116	410.00
IUUC-Dno-028890	Dasypus novemcinctus	70.73	0.00e+00	941.00
IUUC-Dor-031140	Dipodomys ordii	83.28	3.00e-160	558.00
IUUC-Dse-031474	Dothistroma septosporum	29.03	4.00e-09	55.10
IUUC-Ete-032656	Echinops telfairi	74.34	0.00e+00	641.00
IUUC-Eca-033634	Equus caballus	83.81	0.00e+00	1104.00
IUUC-Fca-035845	Felis catus	81.16	0.00e+00	1088.00
IUUC-Fal-037247	Ficedula albicollis	65.33	0.00e+00	862.00
IUUC-Gga-040276	Gallus gallus	65.54	0.00e+00	832.00
IUUC-Gma-044050	Glycine max	28.04	5.00e-09	55.10
IUUC-Ggo-045383	Gorilla gorilla	77.64	0.00e+00	1062.00
IUUC-Hsa-046684	Homo sapiens	77.64	0.00e+00	1030.00
IUUC-Itr-048202	Ictidomys tridecemlineatus	78.15	0.00e+00	1036.00
IUUC-Lch-049841	Latimeria chalumnae	58.64	0.00e+00	689.00
IUUC-Laf-053867	Loxodonta africana	78.90	0.00e+00	1001.00
IUUC-Mcc-055524	Macaca mulatta	79.32	0.00e+00	1063.00
IUUC-Meu-056469	Macropus eugenii	61.79	4.00e-154	538.00
IUUC-Mtr-057682	Medicago truncatula	23.56	2.00e-05	42.70
IUUC-Mga-059265	Meleagris gallopavo	64.41	0.00e+00	828.00
IUUC-Mmr-061107	Microcebus murinus	80.00	0.00e+00	1027.00
IUUC-Mdo-062508	Monodelphis domestica	71.18	0.00e+00	952.00
IUUC-Mmu-063613	Mus musculus	93.91	0.00e+00	1167.00
IUUC-Mac-064775	Musa acuminata	36.36	1.00e-07	49.70
IUUC-Mpu-066673	Mustela putorius furo	81.70	0.00e+00	1054.00
IUUC-Mlu-068057	Myotis lucifugus	76.65	0.00e+00	1056.00
IUUC-Nle-070135	Nomascus leucogenys	76.92	0.00e+00	991.00
IUUC-Oan-073094	Ornithorhynchus anatinus	68.71	0.00e+00	811.00
IUUC-Ocu-074819	Oryctolagus cuniculus	78.90	0.00e+00	1027.00
IUUC-Oga-088835	Otolemur garnettii	81.41	0.00e+00	1065.00
IUUC-Oar-089742	Ovis aries	78.21	0.00e+00	1020.00
IUUC-Ptr-091345	Pan troglodytes	77.64	0.00e+00	1029.00
IUUC-Pan-092316	Papio anubis	77.91	0.00e+00	1060.00
IUUC-Pab-098009	Pongo abelii	76.92	0.00e+00	991.00
IUUC-Pca-100920	Procavia capensis	63.61	1.00e-119	423.00
IUUC-Ppe-101806	Prunus persica	26.53	3.00e-07	48.90
IUUC-Pva-102692	Pteropus vampyrus	75.17	0.00e+00	658.00
IUUC-Sha-106789	Sarcophilus harrisii	72.62	0.00e+00	979.00
IUUC-Smo-109333	Selaginella moellendorffii	34.78	1.00e-06	47.00
IUUC-Sly-111172	Solanum lycopersicum	31.43	1.00e-04	40.40
IUUC-Stu-112768	Solanum tuberosum	31.48	8.00e-05	40.80
IUUC-Ssc-115747	Sus scrofa	81.41	0.00e+00	1051.00
IUUC-Tgu-116653	Taeniopygia guttata	65.59	0.00e+00	850.00
IUUC-Tsy-119559	Tarsius syrichta	69.35	0.00e+00	819.00
IUUC-Tbe-127815	Tupaia belangeri	67.99	0.00e+00	896.00
IUUC-Ttr-129181	Tursiops truncatus	72.50	0.00e+00	644.00
IUUC-Vpa-130759	Vicugna pacos	48.02	1.00e-99	357.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence