iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053857

UUCD1 version

UUC-LoA-00943

Ensembl Protein ID

ENSLAFP00000029111.1

UniProt Accession

G3UMQ2; G3UMQ2_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003315.3	ENSLAFT00000031594.1	ENSLAFP00000029111.1
ENSLAFG00000003315.3	ENSLAFT00000003318.3	ENSLAFP00000002760.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.40e-40	137.7	200	276
E3 activity/RING/RING	2.30e-08	34.8	1084	1189
E3 activity/N-recognin/UBR-box	2.20e-31	108.6	69	139

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al++e++ea++++t+idkeGRravkaG+ya+c+eak++i+++se+++q+pL+Vev
   Q: 200  YYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGAYATCQEAKEDIKSHSENVSQHPLHVEV 276
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiCledf............kd...................................gplvlpCgHvfhadClqkw........... 29
           C++C+e+              +                                   g+++++CgHv+ha C+qk+           
   Q: 1084 CILCQEEQevkiennamvlsACvqkstaltqhrgkpielsgvpetldplfmdpdlayGTYTGSCGHVMHAVCWQKYfeavqlssqqr 1170
           7788554433333322222200222333333333333333333333333333333337999************************** PP
   S: 30   ..pglknssskefrCPlCr 46
             ++l +++s+e +CPlC+
   Q: 1171 ihVDLFDLESGEYLCPLCK 1189
           ******************7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk+get+y+Cr+C++d+t+vlC++Cf+++vHk+H+yk+++s+gggfCdCGdteAw++g++C++++
   Q: 69   QLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQNSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVNHE 139
           68*******************************************************************96 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

WDQQVDFYTA FLHHLAQLVP EIYFAEMDPD LEKQEESVQM SIFTPLEWYL FGEDPDICLE 60
KLKHSGAFQL CGKVFKSGET TYSCRDCAID PTCVLCMDCF QNSVHKNHRY KMHTSTGGGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACAGTGGT GGGATCAGCA AGTTGATTTT TATACCGCTT TCTTGCATCA TTTGGCACAG 60
TTAGTGCCAG AAATTTATTT TGCGGAAATG GACCCTGATT TGGAAAAGCA GGAAGAGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	91.02	0.00e+00	3163.00
IUUC-Apl-004160	Anas platyrhynchos	76.09	0.00e+00	2648.00
IUUC-Aca-004982	Anolis carolinensis	74.04	0.00e+00	2575.00
IUUC-Ago-007752	Ashbya gossypii	26.71	4.00e-22	101.00
IUUC-Acl-008055	Aspergillus clavatus	23.88	7.00e-34	140.00
IUUC-Ani-009334	Aspergillus nidulans	22.71	4.00e-49	191.00
IUUC-Ate-010550	Aspergillus terreus	22.55	3.00e-46	181.00
IUUC-Ame-011231	Astyanax mexicanus	55.68	0.00e+00	1822.00
IUUC-Bgr-011999	Blumeria graminis	23.06	2.00e-46	182.00
IUUC-Bta-012347	Bos taurus	90.39	0.00e+00	3143.00
IUUC-Bci-013834	Botrytis cinerea	23.22	1.00e-43	173.00
IUUC-Cja-018911	Callithrix jacchus	90.14	0.00e+00	3111.00
IUUC-Cfa-020991	Canis familiaris	92.22	0.00e+00	3202.00
IUUC-Cpo-021448	Cavia porcellus	88.74	0.00e+00	3118.00
IUUC-Cre-022930	Chlamydomonas reinhardtii	46.15	2.20e-02	30.80
IUUC-Csa-024255	Chlorocebus sabaeus	91.24	0.00e+00	2604.00
IUUC-Cho-024550	Choloepus hoffmanni	70.75	0.00e+00	1602.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	24.16	2.00e-48	189.00
IUUC-Dno-029427	Dasypus novemcinctus	89.26	0.00e+00	3079.00
IUUC-Dor-031073	Dipodomys ordii	83.37	0.00e+00	1343.00
IUUC-Ete-032318	Echinops telfairi	74.40	0.00e+00	1200.00
IUUC-Eca-033348	Equus caballus	90.46	0.00e+00	2950.00
IUUC-Eeu-034664	Erinaceus europaeus	81.32	0.00e+00	2816.00
IUUC-Fca-035604	Felis catus	85.83	0.00e+00	2917.00
IUUC-Fal-037333	Ficedula albicollis	75.77	0.00e+00	2608.00
IUUC-Fox-037984	Fusarium oxysporum	25.78	2.00e-37	152.00
IUUC-Gmo-039363	Gadus morhua	54.35	0.00e+00	1593.00
IUUC-Gga-040486	Gallus gallus	75.10	0.00e+00	2552.00
IUUC-Gac-041985	Gasterosteus aculeatus	55.47	0.00e+00	1672.00
IUUC-Ggo-044704	Gorilla gorilla	84.11	0.00e+00	2444.00
IUUC-Hsa-046753	Homo sapiens	91.76	0.00e+00	3175.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	90.87	0.00e+00	3132.00
IUUC-Lch-049904	Latimeria chalumnae	61.65	0.00e+00	2117.00
IUUC-Loc-052624	Lepisosteus oculatus	59.67	0.00e+00	1987.00
IUUC-Mcc-054873	Macaca mulatta	91.88	0.00e+00	3155.00
IUUC-Meu-056858	Macropus eugenii	66.13	0.00e+00	1028.00
IUUC-Mga-059917	Meleagris gallopavo	75.83	0.00e+00	2659.00
IUUC-Mmr-061128	Microcebus murinus	88.22	0.00e+00	2985.00
IUUC-Mdo-062306	Monodelphis domestica	78.42	0.00e+00	2721.00
IUUC-Mmu-063389	Mus musculus	88.76	0.00e+00	3099.00
IUUC-Mpu-065983	Mustela putorius furo	91.65	0.00e+00	3191.00
IUUC-Mlu-068013	Myotis lucifugus	88.00	0.00e+00	3058.00
IUUC-Nle-070031	Nomascus leucogenys	92.05	0.00e+00	3186.00
IUUC-Opr-070551	Ochotona princeps	70.33	0.00e+00	1320.00
IUUC-Ont-072035	Oreochromis niloticus	56.66	0.00e+00	1914.00
IUUC-Ocu-074930	Oryctolagus cuniculus	89.25	0.00e+00	3089.00
IUUC-Oba-075295	Oryza barthii	38.54	4.00e-14	74.70
IUUC-Ogu-078497	Oryza glumaepatula	38.54	4.00e-14	74.70
IUUC-Oin-079343	Oryza indica	38.54	4.00e-14	74.70
IUUC-Ome-081738	Oryza meridionalis	35.51	4.00e-13	71.60
IUUC-Oni-083099	Oryza nivara	38.54	5.00e-14	74.70
IUUC-Oru-084471	Oryza rufipogon	38.54	4.00e-14	74.70
IUUC-Osa-086106	Oryza sativa	36.23	3.00e-13	70.90
IUUC-Ola-086683	Oryzias latipes	55.73	0.00e+00	1840.00
IUUC-Olu-087863	Ostreococcus lucimarinus	34.88	6.80e-02	32.00
IUUC-Oga-088017	Otolemur garnettii	87.19	0.00e+00	2997.00
IUUC-Oar-089557	Ovis aries	89.59	0.00e+00	3123.00
IUUC-Ptr-091366	Pan troglodytes	90.56	0.00e+00	3147.00
IUUC-Pan-092184	Papio anubis	91.76	0.00e+00	3152.00
IUUC-Psi-093720	Pelodiscus sinensis	77.11	0.00e+00	2611.00
IUUC-Pno-094877	Phaeosphaeria nodorum	22.51	4.00e-36	148.00
IUUC-Pfo-097124	Poecilia formosa	55.71	0.00e+00	1862.00
IUUC-Pab-098586	Pongo abelii	91.87	0.00e+00	3183.00
IUUC-Pop-099496	Populus trichocarpa	24.05	4.00e-24	107.00
IUUC-Pca-100673	Procavia capensis	85.12	0.00e+00	1699.00
IUUC-Pva-102724	Pteropus vampyrus	92.70	0.00e+00	2248.00
IUUC-Pte-104174	Pyrenophora teres	22.43	8.00e-49	190.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	22.41	2.00e-48	189.00
IUUC-Rno-105474	Rattus norvegicus	84.53	0.00e+00	2207.00
IUUC-Sha-106993	Sarcophilus harrisii	79.25	0.00e+00	2795.00
IUUC-Sar-113447	Sorex araneus	85.98	0.00e+00	2054.00
IUUC-Ssc-115768	Sus scrofa	86.18	0.00e+00	2807.00
IUUC-Tgu-116949	Taeniopygia guttata	72.86	0.00e+00	2472.00
IUUC-Tru-117782	Takifugu rubripes	55.84	0.00e+00	1884.00
IUUC-Tsy-119177	Tarsius syrichta	79.36	0.00e+00	2118.00
IUUC-Tni-120884	Tetraodon nigroviridis	51.74	0.00e+00	1695.00
IUUC-Tbe-128088	Tupaia belangeri	76.50	0.00e+00	1160.00
IUUC-Ttr-129062	Tursiops truncatus	84.39	0.00e+00	2889.00
IUUC-Uma-129344	Ustilago maydis	23.51	9.00e-56	213.00
IUUC-Vpa-130578	Vicugna pacos	86.11	0.00e+00	1721.00
IUUC-Vvi-130900	Vitis vinifera	44.79	7.00e-13	68.20
IUUC-Xtr-132244	Xenopus tropicalis	60.50	0.00e+00	2080.00
IUUC-Xma-134112	Xiphophorus maculatus	56.21	0.00e+00	1866.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence