iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000015857.1	ENSONIT00000019983.1	ENSONIP00000019966.1
ENSONIG00000015857.1	ENSONIT00000019984.1	ENSONIP00000019967.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.30e-63	213.9	168	660

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+++l+l+       ++l+++++++++ +++++l++lf+ ++ sk+k+v+p++ +++lk++ ++ s
   Q: 168  VGLKNVGNTCWFSAVIQSLFNLLEFQRLVLNysppARVHDLPRNQKEHRNLPFMQELRNLFSLMVGSKRKYVDPSRAVEILKDAFKS-S 255
           6******************************98887788888888899999*******************************99998.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +++qqD++Ef++ lld le+++++                  + +e+++ +k k+++++lF g++    +    +++ + +e f +++l
   Q: 256  ESQQQDVSEFTHKLLDWLEDAFQM------------------KAEEDREGEKPKNPMVELFYGRFLAVGVH--EGKKFENTEMFGQYPL 324
           9*********************32..................2245788999**************77766..456667799******* PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++ +   + ++ +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp +L +++
   Q: 325  QVNGFK-----DLHECLEAAMIEGEIES---LHSAEN--SARSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMLYMDR 403
           ******.....9**************96...555444..445689******************************************** PP
   S: 264  fcts..................................................................................... 267
           ++ +                                                                                     
   Q: 404  YMDRnreitrikreeirrlkehltllqqrlerylsygsgpkrfpladvlqyamefasskpvctspvedidtsappggttgqqlpppsta 492
           ****8888888888888888888888888888888888888888888888888888888888888777777777777777777777666 PP
   S: 268  .........................peekqke......................................................... 274
                                    +     +                                                         
   Q: 493  eqdslpplessglasgpatapsaaqQ-----Qrvpihkpftqsrlppdlpmhpaprhiteeelrvlegclhrwrsevendtrdlqgsit 576
           66666666666666666666544440.....1566666666666666666666666666666666667777777777777777777888 PP
   S: 275  ................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                           ++ Y+L+av+vH+G+++ GHY+ay+++ +++ W++++D +Vt++++ee ++++      ++aY+l+Y 
   Q: 577  rihrtielmysdksmmQVPYRLHAVLVHEGQANAGHYWAYIYDPHQRcWMKYNDISVTKSSWEELVRDSFggyrnASAYCLMYI 660
           8888888888888888***************************88878***************99997779************6 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTVEQNVLQQ HSQKHQQTLL NQLREVTGTT DVQLLQQALQ VSNGDLGEAV AFLTEKNAKV 60
PQQDETTYYQ TSQVASDRYI SVGSQADTNV IDLTGDDKDD LQRAIALSLE ESNRAFRETG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGTTAA AATGAATCGC AAAATTTCTG GCTATAATTG TAGTTTACAT TCATTTTCCC 60
CAAAAGTCCC GTTCGTGACG GTAACCTAGT TCAACAGACC TGAGTAATCG ATCCCAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0009953--P:dorsal/ventral pattern formation
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	71.79	0.00e+00	1647.00
IUUC-Apl-004030	Anas platyrhynchos	72.83	0.00e+00	1719.00
IUUC-Aca-004741	Anolis carolinensis	45.30	0.00e+00	954.00
IUUC-Ani-009503	Aspergillus nidulans	33.02	6.00e-11	63.50
IUUC-Ate-010275	Aspergillus terreus	22.79	5.00e-15	77.40
IUUC-Ame-010624	Astyanax mexicanus	74.74	0.00e+00	1239.00
IUUC-Bta-013166	Bos taurus	75.56	0.00e+00	1162.00
IUUC-Cja-019150	Callithrix jacchus	73.61	0.00e+00	1717.00
IUUC-Cfa-020649	Canis familiaris	74.12	0.00e+00	1717.00
IUUC-Cpo-021807	Cavia porcellus	71.10	0.00e+00	1687.00
IUUC-Csa-023388	Chlorocebus sabaeus	73.36	0.00e+00	1719.00
IUUC-Cho-024343	Choloepus hoffmanni	73.91	5.00e-124	439.00
IUUC-Cin-025302	Ciona intestinalis	37.88	2.00e-99	356.00
IUUC-Csv-025911	Ciona savignyi	40.84	9.00e-99	355.00
IUUC-Cgl-026575	Colletotrichum gloeosporioides	53.19	3.00e-10	61.20
IUUC-Dre-028016	Danio rerio	83.16	0.00e+00	1888.00
IUUC-Dno-029495	Dasypus novemcinctus	71.89	0.00e+00	1699.00
IUUC-Dor-030948	Dipodomys ordii	60.93	0.00e+00	1139.00
IUUC-Fca-035876	Felis catus	75.69	0.00e+00	1189.00
IUUC-Fal-036762	Ficedula albicollis	76.48	0.00e+00	1047.00
IUUC-Fox-037752	Fusarium oxysporum	23.93	1.00e-14	75.90
IUUC-Gmo-039490	Gadus morhua	80.24	0.00e+00	1849.00
IUUC-Gga-040817	Gallus gallus	75.50	0.00e+00	1784.00
IUUC-Gac-042473	Gasterosteus aculeatus	85.03	0.00e+00	1958.00
IUUC-Ggo-044939	Gorilla gorilla	70.11	0.00e+00	1600.00
IUUC-Hsa-046204	Homo sapiens	75.34	0.00e+00	1193.00
IUUC-Lch-049572	Latimeria chalumnae	74.12	0.00e+00	1710.00
IUUC-Loc-052070	Lepisosteus oculatus	82.64	0.00e+00	1895.00
IUUC-Lma-053078	Leptosphaeria maculans	30.56	3.00e-11	65.10
IUUC-Laf-054426	Loxodonta africana	75.35	0.00e+00	1084.00
IUUC-Mcc-055858	Macaca mulatta	73.53	0.00e+00	1739.00
IUUC-Meu-056719	Macropus eugenii	61.96	4.00e-157	549.00
IUUC-Mga-059808	Meleagris gallopavo	77.29	0.00e+00	1250.00
IUUC-Mmr-060987	Microcebus murinus	73.87	0.00e+00	1710.00
IUUC-Mdo-061955	Monodelphis domestica	49.82	0.00e+00	1038.00
IUUC-Mmu-064245	Mus musculus	73.98	0.00e+00	1192.00
IUUC-Mpu-066304	Mustela putorius furo	73.73	0.00e+00	1704.00
IUUC-Mlu-067139	Myotis lucifugus	75.25	0.00e+00	1214.00
IUUC-Nle-069075	Nomascus leucogenys	74.15	0.00e+00	1194.00
IUUC-Oan-073054	Ornithorhynchus anatinus	67.47	0.00e+00	1533.00
IUUC-Ocu-074102	Oryctolagus cuniculus	71.98	0.00e+00	1704.00
IUUC-Ola-086529	Oryzias latipes	82.72	0.00e+00	1893.00
IUUC-Oga-088939	Otolemur garnettii	75.28	0.00e+00	1179.00
IUUC-Oar-090266	Ovis aries	73.81	0.00e+00	1686.00
IUUC-Ptr-090546	Pan troglodytes	75.46	0.00e+00	1194.00
IUUC-Pan-092311	Papio anubis	73.44	0.00e+00	1738.00
IUUC-Psi-093459	Pelodiscus sinensis	83.39	0.00e+00	1099.00
IUUC-Pfo-096726	Poecilia formosa	91.88	0.00e+00	2111.00
IUUC-Pab-097608	Pongo abelii	71.28	0.00e+00	1624.00
IUUC-Pca-100718	Procavia capensis	62.64	0.00e+00	1137.00
IUUC-Pva-103150	Pteropus vampyrus	66.74	0.00e+00	1196.00
IUUC-Rno-105727	Rattus norvegicus	74.13	0.00e+00	1178.00
IUUC-Sha-107051	Sarcophilus harrisii	76.89	0.00e+00	1217.00
IUUC-Sar-113097	Sorex araneus	66.00	0.00e+00	1489.00
IUUC-Ssc-115877	Sus scrofa	75.22	0.00e+00	1183.00
IUUC-Tgu-117473	Taeniopygia guttata	76.81	0.00e+00	1253.00
IUUC-Tru-118135	Takifugu rubripes	70.83	0.00e+00	1559.00
IUUC-Tsy-119471	Tarsius syrichta	68.54	0.00e+00	1469.00
IUUC-Tni-120139	Tetraodon nigroviridis	76.37	0.00e+00	1128.00
IUUC-Tbe-127549	Tupaia belangeri	66.26	0.00e+00	1482.00
IUUC-Ttr-128896	Tursiops truncatus	67.81	0.00e+00	1529.00
IUUC-Vda-129742	Verticillium dahliae	23.19	7.00e-11	63.90
IUUC-Vpa-130500	Vicugna pacos	77.65	0.00e+00	1108.00
IUUC-Xtr-132896	Xenopus tropicalis	74.81	0.00e+00	1222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence