iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045086

UUCD1 version

UUC-GoG-00889

Ensembl Protein ID

ENSGGOP00000024606.1

UniProt Accession

G3S941; G3S941_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000009103.2	ENSGGOT00000032424.1	ENSGGOP00000024606.1
ENSGGOG00000009103.2	ENSGGOT00000009142.2	ENSGGOP00000008897.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-06	29.3	14	57
E3 activity/RING/U-box	5.10e-06	26.9	10	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++  CgH f++ Cl ++      + ++ +CP C+
   Q: 14   CPLCLQLFDA-PVTAECGHSFCRACLGRV-AGEPAADGTVLCPCCQ 57
           ********99.999***************.5555799999*****7 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl...asggk....tcPvtrqplteedlvPnltlrrliq 66
           +e+ Cp+ l+l+  Pv++++G+++ r+++ +     a         cP +++p++++ l  nl l rl++
   Q: 10   QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAgepA---AdgtvLCPCCQAPTRPQALSTNLQLARLVE 76
           7899***************************765553...144479****************99988765 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCRACLGR VAGEPAADGT VLCPCCQAPT 60
RPQALSTNLQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RALVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGCTG CGCCCGGCCT CCTGCACCAG GAGCTGTCCT GCCCGCTGTG CCTGCAGCTG 60
TTCGACGCGC CCGTGACAGC CGAGTGCGGC CACAGTTTCT GCCGCGCCTG CCTAGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	73.33	1.00e-142	499.00
IUUC-Aca-004755	Anolis carolinensis	63.16	1.00e-136	479.00
IUUC-Bta-013476	Bos taurus	75.06	2.00e-166	578.00
IUUC-Cja-018969	Callithrix jacchus	85.03	4.00e-172	597.00
IUUC-Cfa-020155	Canis familiaris	94.06	0.00e+00	700.00
IUUC-Cpo-021646	Cavia porcellus	90.96	0.00e+00	680.00
IUUC-Cre-022560	Chlamydomonas reinhardtii	44.90	1.00e-05	45.10
IUUC-Csa-023855	Chlorocebus sabaeus	98.78	1.00e-130	459.00
IUUC-Dno-029142	Dasypus novemcinctus	92.76	0.00e+00	656.00
IUUC-Dor-030394	Dipodomys ordii	89.92	6.00e-64	238.00
IUUC-Ete-032801	Echinops telfairi	80.95	1.00e-41	163.00
IUUC-Eca-034378	Equus caballus	95.61	0.00e+00	722.00
IUUC-Eeu-034526	Erinaceus europaeus	87.27	2.00e-179	621.00
IUUC-Fca-036440	Felis catus	94.83	0.00e+00	717.00
IUUC-Hsa-046533	Homo sapiens	100.00	0.00e+00	717.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	95.09	0.00e+00	715.00
IUUC-Laf-054479	Loxodonta africana	94.83	0.00e+00	708.00
IUUC-Mcc-055814	Macaca mulatta	97.17	0.00e+00	683.00
IUUC-Meu-056767	Macropus eugenii	75.79	4.00e-162	564.00
IUUC-Mmr-061616	Microcebus murinus	96.38	0.00e+00	721.00
IUUC-Mdo-062252	Monodelphis domestica	77.69	4.00e-170	590.00
IUUC-Mmu-063094	Mus musculus	93.28	0.00e+00	682.00
IUUC-Mpu-065885	Mustela putorius furo	76.49	9.00e-157	546.00
IUUC-Mlu-068150	Myotis lucifugus	64.81	8.00e-85	306.00
IUUC-Nle-069476	Nomascus leucogenys	99.48	0.00e+00	710.00
IUUC-Opr-070871	Ochotona princeps	92.79	2.00e-144	505.00
IUUC-Oan-072738	Ornithorhynchus anatinus	77.69	4.00e-170	590.00
IUUC-Ocu-074132	Oryctolagus cuniculus	95.04	0.00e+00	664.00
IUUC-Oga-088268	Otolemur garnettii	60.82	6.00e-105	374.00
IUUC-Oar-089555	Ovis aries	87.08	2.00e-151	528.00
IUUC-Ptr-090792	Pan troglodytes	100.00	0.00e+00	717.00
IUUC-Pan-092897	Papio anubis	99.22	0.00e+00	713.00
IUUC-Pab-098716	Pongo abelii	99.74	0.00e+00	715.00
IUUC-Pca-100618	Procavia capensis	83.98	4.00e-176	610.00
IUUC-Pva-102430	Pteropus vampyrus	83.46	3.00e-174	604.00
IUUC-Rno-105665	Rattus norvegicus	92.76	0.00e+00	704.00
IUUC-Sha-106854	Sarcophilus harrisii	63.87	8.00e-134	470.00
IUUC-Sar-113028	Sorex araneus	90.65	6.00e-122	430.00
IUUC-Ssc-116124	Sus scrofa	95.09	0.00e+00	687.00
IUUC-Tbe-127273	Tupaia belangeri	92.57	2.00e-77	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence