iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090992

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03015188

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000012282.3	ENSPTRT00000063874.1	ENSPTRP00000055419.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-06	28.3	272	310
E3 activity/RING/U-box	5.00e-07	29.7	269	315

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  +++ p+++pCgH+f+++Cl++          + +CPlC+
   Q: 272  CALCMRLLFE-PVTTPCGHTFCLKCLERC------LDHAPHCPLCK 310
           **********.9**************999......9*********7 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           +f C++ + l  +Pv++p+G+t+  +++e++l++  + cP+++ +l+e
   Q: 269  DFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPH-CPLCKDKLSE 315
           79***********************************.******9976 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

RVNVVLSVLL EKCFPAECRL RRLAGQARSL QRQQQPEAAL LRCDQALELA PDDNSLLLLR 60
AELYLTMKNY EQALQDASAA CQNEPLLIKG HQVKAQALSG LGRSKEVLKE FLYCLALNPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGTGAACG TGGTGCTGAG CGTGCTGCTG GAGAAGTGCT TCCCGGCCGA GTGCCGGCTG 60
CGCAGGCTGG CAGGCCAGGC GCGGAGCCTG CAGCGCCAGC AGCAGCCGGA GGCCGCGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	87.16	0.00e+00	985.00
IUUC-Apl-003355	Anas platyrhynchos	63.35	0.00e+00	679.00
IUUC-Aca-004822	Anolis carolinensis	60.55	0.00e+00	694.00
IUUC-Acl-008224	Aspergillus clavatus	31.96	6.00e-41	161.00
IUUC-Afu-008802	Aspergillus fumigatus	30.00	8.00e-38	151.00
IUUC-Ani-009473	Aspergillus nidulans	31.90	7.00e-42	165.00
IUUC-Ate-010489	Aspergillus terreus	32.40	7.00e-40	158.00
IUUC-Cja-019041	Callithrix jacchus	92.91	0.00e+00	1045.00
IUUC-Cfa-020025	Canis familiaris	87.18	0.00e+00	960.00
IUUC-Cre-022730	Chlamydomonas reinhardtii	49.09	2.00e-09	55.80
IUUC-Csa-023324	Chlorocebus sabaeus	98.63	0.00e+00	1015.00
IUUC-Cin-025668	Ciona intestinalis	34.27	2.00e-87	316.00
IUUC-Cne-026875	Cryptococcus neoformans	28.57	4.00e-08	53.10
IUUC-Dre-028400	Danio rerio	51.19	3.00e-145	508.00
IUUC-Eeu-034779	Erinaceus europaeus	66.54	0.00e+00	642.00
IUUC-Fca-036276	Felis catus	87.33	0.00e+00	983.00
IUUC-Fal-036669	Ficedula albicollis	61.19	0.00e+00	689.00
IUUC-Fso-038334	Fusarium solani	29.77	4.00e-41	162.00
IUUC-Gmo-039511	Gadus morhua	68.79	3.00e-117	415.00
IUUC-Gga-041253	Gallus gallus	61.35	0.00e+00	704.00
IUUC-Gma-042919	Glycine max	34.21	7.00e-39	154.00
IUUC-Ggo-045501	Gorilla gorilla	99.13	0.00e+00	1119.00
IUUC-Hsa-046630	Homo sapiens	99.48	0.00e+00	1121.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	81.42	0.00e+00	823.00
IUUC-Lch-049788	Latimeria chalumnae	53.55	1.00e-173	603.00
IUUC-Laf-054421	Loxodonta africana	62.29	0.00e+00	675.00
IUUC-Mcc-054828	Macaca mulatta	98.04	0.00e+00	1011.00
IUUC-Meu-055901	Macropus eugenii	52.49	2.00e-167	582.00
IUUC-Mtr-058075	Medicago truncatula	36.96	8.00e-44	171.00
IUUC-Mga-059760	Meleagris gallopavo	61.70	0.00e+00	680.00
IUUC-Mmr-061350	Microcebus murinus	85.53	0.00e+00	901.00
IUUC-Mdo-062203	Monodelphis domestica	64.88	0.00e+00	749.00
IUUC-Mmu-064118	Mus musculus	79.00	0.00e+00	795.00
IUUC-Mpu-065764	Mustela putorius furo	86.30	0.00e+00	979.00
IUUC-Nfi-068337	Neosartorya fischeri	31.75	3.00e-38	152.00
IUUC-Nle-069616	Nomascus leucogenys	98.96	0.00e+00	1118.00
IUUC-Ont-072142	Oreochromis niloticus	51.03	3.00e-157	549.00
IUUC-Oga-088972	Otolemur garnettii	88.06	0.00e+00	995.00
IUUC-Pan-092180	Papio anubis	96.37	0.00e+00	1082.00
IUUC-Psi-093423	Pelodiscus sinensis	62.70	0.00e+00	666.00
IUUC-Pab-097974	Pongo abelii	98.79	0.00e+00	1113.00
IUUC-Ppe-101621	Prunus persica	39.49	6.00e-36	145.00
IUUC-Pva-102269	Pteropus vampyrus	80.48	0.00e+00	875.00
IUUC-Pgr-103289	Puccinia graminis	26.78	1.00e-27	117.00
IUUC-Rno-105905	Rattus norvegicus	80.22	0.00e+00	824.00
IUUC-Spo-108344	Schizosaccharomyces pombe	30.94	4.00e-25	109.00
IUUC-Tgu-117000	Taeniopygia guttata	61.42	0.00e+00	711.00
IUUC-Tru-118016	Takifugu rubripes	49.82	2.00e-146	513.00
IUUC-Ttr-128666	Tursiops truncatus	79.93	0.00e+00	882.00
IUUC-Uma-129541	Ustilago maydis	33.98	8.00e-34	139.00
IUUC-Vpa-130334	Vicugna pacos	65.41	5.00e-175	607.00
IUUC-Vvi-130910	Vitis vinifera	34.33	1.00e-39	157.00
IUUC-Xtr-132065	Xenopus tropicalis	53.63	4.00e-171	594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence