iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.50e-13	50.2	83	150
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.40e-10	38.0	185	215

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmele..esksklmveikdvqpevfrallkFlYtgklde 67
           +Dv ++ g    +ah++vL+a+S +F+a+f  el   e k ++ v+++ ++ + +  ll+F+Ytg+ ++
   Q: 83   CDVEIIAGMATLSAHRAVLSAASAYFEAMFRPELGlnEVK-QKSVVLHTIDGDILHILLDFIYTGRCEI 150
           8*****************************7777762666.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +N+lgilrfA++++c+ L+++al+f++ +F+
   Q: 185  SNALGILRFAEAHNCESLAKSALNFVHANFP 215
           8*****************************6 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPPLKTYQIH EYNGNTSPNA NANQNANQNP TGGGGDGDFF GQNLGSGATA ASHRTNLPSY 60
CNAQYPFKVL SNLNQLREQS RFCDVEIIAG MATLSAHRAV LSAASAYFEA MFRPELGLNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCGCCCAA AAACATCGAC TCCAGTTCCA GCTACATACT AAAGTGCATT GAAAAGTCAA 60
AGAAATATGC CAGTTTGTAA ATATTAAAAA CACTATTTCA TCTTAATGGG GAAATAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0003779--F:actin binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0051726--P:regulation of cell cycle

KEGG

dme:Dmel_CG9426

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001672	Ailuropoda melanoleuca	37.50	9.00e-109	386.00
IUUC-Apl-003849	Anas platyrhynchos	38.03	3.00e-109	388.00
IUUC-Aca-004563	Anolis carolinensis	37.08	7.00e-103	367.00
IUUC-Bta-013512	Bos taurus	37.68	1.00e-108	386.00
IUUC-Cja-018771	Callithrix jacchus	37.85	2.00e-109	389.00
IUUC-Cfa-020097	Canis familiaris	38.12	6.00e-102	363.00
IUUC-Cpo-022161	Cavia porcellus	37.32	2.00e-107	382.00
IUUC-Csa-024249	Chlorocebus sabaeus	37.50	1.00e-108	385.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	25.99	1.00e-18	86.30
IUUC-Dno-029046	Dasypus novemcinctus	37.07	2.00e-108	385.00
IUUC-Ete-032968	Echinops telfairi	33.28	5.00e-95	340.00
IUUC-Fca-036451	Felis catus	37.85	7.00e-110	390.00
IUUC-Fal-036931	Ficedula albicollis	39.44	2.00e-113	401.00
IUUC-Gga-040552	Gallus gallus	38.20	6.00e-110	390.00
IUUC-Hsa-045757	Homo sapiens	37.50	2.00e-108	385.00
IUUC-Itr-048686	Ictidomys tridecemlineatus	36.97	9.00e-108	383.00
IUUC-Laf-053779	Loxodonta africana	35.21	4.00e-99	354.00
IUUC-Mcc-054862	Macaca mulatta	37.74	1.00e-101	362.00
IUUC-Mor-057181	Magnaporthe oryzae	22.15	5.00e-08	51.20
IUUC-Mga-060083	Meleagris gallopavo	38.20	2.00e-110	392.00
IUUC-Mmr-061303	Microcebus murinus	35.82	2.00e-91	328.00
IUUC-Mdo-062064	Monodelphis domestica	38.73	3.00e-111	394.00
IUUC-Mmu-063410	Mus musculus	36.16	3.00e-107	381.00
IUUC-Mpu-066841	Mustela putorius furo	38.12	5.00e-102	364.00
IUUC-Mlu-067053	Myotis lucifugus	37.28	3.00e-104	371.00
IUUC-Oan-073110	Ornithorhynchus anatinus	37.35	9.00e-107	380.00
IUUC-Oga-088373	Otolemur garnettii	37.85	2.00e-110	392.00
IUUC-Oar-089314	Ovis aries	37.85	2.00e-109	389.00
IUUC-Ptr-090515	Pan troglodytes	37.93	2.00e-101	362.00
IUUC-Pan-092367	Papio anubis	37.50	1.00e-108	385.00
IUUC-Psi-093109	Pelodiscus sinensis	37.01	2.00e-108	385.00
IUUC-Pma-094467	Petromyzon marinus	35.23	2.00e-73	269.00
IUUC-Pab-098529	Pongo abelii	36.31	1.00e-83	302.00
IUUC-Rno-105294	Rattus norvegicus	36.97	1.00e-107	382.00
IUUC-Sha-106587	Sarcophilus harrisii	37.23	3.00e-112	398.00
IUUC-Sar-113688	Sorex araneus	37.68	9.00e-108	383.00
IUUC-Tgu-117449	Taeniopygia guttata	39.08	5.00e-113	400.00
IUUC-Vpa-130752	Vicugna pacos	37.39	2.00e-105	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence