iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-066966

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02052313

Gene Name

OTUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012235.2	ENSMLUT00000012239.2	ENSMLUP00000011150.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	2.60e-51	173.7	111	301

Active Site

Position(s)	Description	Evidence
118	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
121	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
295		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+kt++DGnC++rA+++s                                                          ll++f+d+s+sd
   Q: 111  YIRKTRPDGNCFYRAFGFShleallddskelqrfkavsakskedlvsqgfteftiedfhntfmdlieqvekqtsvadLLASFNDQSTSD 199
           89*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           +lv++Lr+lts ylq+es+ff++fie+++++kefcq++vep++k +++ihi+aLaq+L+++i+v+++d++e   gg+++p++fpe + +
   Q: 200  YLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKeSDHIHIIALAQALNVSIQVEYMDRGE---GGTTNPHIFPEGS-E 284
           **********************************************************************9...9************.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlYr+gHYd+L++
   Q: 285  PKVYLLYRPGHYDILYK 301
           ***************96 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

CQGGVTRRGS LPGGGQLVTR KRSAVRRCLK MAAEEPQQQK QEPLGSDAEG VNCLAYDEAI 60
MAQQDRIQQE IAVQNPLVSE RLELSVLYKE YAEDDNIYQQ KIKDLHKKYS YIRKTRPDGN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCAGGGAG GGGTCACGAG GAGGGGCTCG CTTCCGGGCG GAGGACAACT GGTAACCCGG 60
AAGCGGTCAG CAGTGCGGCG CTGTTTAAAG ATGGCGGCGG AGGAACCTCA GCAGCAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030298--OTUB1
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001871	Ailuropoda melanoleuca	96.68	1.00e-170	591.00
IUUC-Apl-003233	Anas platyrhynchos	58.46	9.00e-19	84.30
IUUC-Aca-004648	Anolis carolinensis	85.77	9.00e-138	482.00
IUUC-Aly-005710	Arabidopsis lyrata	42.12	6.00e-52	197.00
IUUC-Ath-007112	Arabidopsis thaliana	41.97	6.00e-51	194.00
IUUC-Afl-008439	Aspergillus flavus	34.18	3.00e-08	52.00
IUUC-Ame-010662	Astyanax mexicanus	83.27	1.00e-130	458.00
IUUC-Bta-013533	Bos taurus	98.15	6.00e-152	529.00
IUUC-Bol-016100	Brassica oleracea	39.66	2.00e-50	192.00
IUUC-Bra-017705	Brassica rapa	37.13	2.00e-45	176.00
IUUC-Cel-018295	Caenorhabditis elegans	34.78	5.00e-42	164.00
IUUC-Cja-019190	Callithrix jacchus	98.34	9.00e-171	592.00
IUUC-Cfa-020430	Canis familiaris	99.60	4.00e-149	520.00
IUUC-Cpo-022355	Cavia porcellus	98.89	3.00e-153	534.00
IUUC-Cre-022997	Chlamydomonas reinhardtii	38.46	4.00e-46	178.00
IUUC-Csa-023286	Chlorocebus sabaeus	96.07	8.00e-151	525.00
IUUC-Cin-025507	Ciona intestinalis	43.33	3.00e-44	171.00
IUUC-Csv-026273	Ciona savignyi	49.80	7.00e-69	253.00
IUUC-Dre-027843	Danio rerio	79.70	7.00e-127	446.00
IUUC-Dno-029165	Dasypus novemcinctus	98.50	2.00e-117	414.00
IUUC-Dor-030943	Dipodomys ordii	98.89	3.00e-153	534.00
IUUC-Dme-031922	Drosophila melanogaster	56.40	2.00e-78	285.00
IUUC-Ete-032296	Echinops telfairi	95.60	4.00e-89	321.00
IUUC-Eca-033695	Equus caballus	98.41	9.00e-148	515.00
IUUC-Fca-036441	Felis catus	92.81	2.00e-149	521.00
IUUC-Gmo-038908	Gadus morhua	79.12	6.00e-127	446.00
IUUC-Ggr-040020	Gaeumannomyces graminis	31.41	4.00e-33	136.00
IUUC-Gga-040460	Gallus gallus	81.92	1.00e-133	468.00
IUUC-Gac-042417	Gasterosteus aculeatus	81.20	1.00e-122	432.00
IUUC-Gma-043712	Glycine max	41.13	7.00e-52	197.00
IUUC-Ggo-044552	Gorilla gorilla	99.37	4.00e-92	330.00
IUUC-Hsa-046766	Homo sapiens	99.26	1.00e-153	535.00
IUUC-Itr-048312	Ictidomys tridecemlineatus	98.89	3.00e-153	534.00
IUUC-Lch-050602	Latimeria chalumnae	81.75	1.00e-119	422.00
IUUC-Laf-053705	Loxodonta africana	98.89	3.00e-153	534.00
IUUC-Mcc-055745	Macaca mulatta	93.08	9.00e-150	522.00
IUUC-Meu-056569	Macropus eugenii	85.61	2.00e-135	474.00
IUUC-Mtr-057712	Medicago truncatula	43.49	1.00e-46	179.00
IUUC-Mvi-060358	Microbotryum violaceum	33.94	2.00e-15	75.90
IUUC-Mmr-061123	Microcebus murinus	99.57	3.00e-128	451.00
IUUC-Mdo-062613	Monodelphis domestica	86.40	8.00e-124	436.00
IUUC-Mmu-063658	Mus musculus	98.89	3.00e-153	534.00
IUUC-Mac-065274	Musa acuminata	37.60	3.00e-39	155.00
IUUC-Mpu-066172	Mustela putorius furo	99.26	1.00e-153	535.00
IUUC-Nle-069519	Nomascus leucogenys	87.63	6.00e-93	333.00
IUUC-Ont-071901	Oreochromis niloticus	82.47	4.00e-125	440.00
IUUC-Ola-087331	Oryzias latipes	81.46	1.00e-86	311.00
IUUC-Oga-088064	Otolemur garnettii	99.26	1.00e-153	535.00
IUUC-Oar-089251	Ovis aries	97.64	4.00e-147	513.00
IUUC-Ptr-091430	Pan troglodytes	98.01	1.00e-169	588.00
IUUC-Psi-093823	Pelodiscus sinensis	88.12	1.00e-134	471.00
IUUC-Pma-094366	Petromyzon marinus	72.01	1.00e-103	368.00
IUUC-Pfo-096734	Poecilia formosa	81.27	1.00e-114	405.00
IUUC-Pab-097919	Pongo abelii	99.14	2.00e-126	444.00
IUUC-Pop-099401	Populus trichocarpa	41.24	2.00e-48	186.00
IUUC-Ppe-101977	Prunus persica	42.38	1.00e-51	197.00
IUUC-Pva-102499	Pteropus vampyrus	99.60	7.00e-149	519.00
IUUC-Rno-105233	Rattus norvegicus	98.89	3.00e-153	534.00
IUUC-Sha-107081	Sarcophilus harrisii	92.98	3.00e-156	544.00
IUUC-Sly-111640	Solanum lycopersicum	42.01	3.00e-49	188.00
IUUC-Ssc-116202	Sus scrofa	99.26	1.00e-153	535.00
IUUC-Tru-117664	Takifugu rubripes	76.90	2.00e-123	434.00
IUUC-Tca-121467	Theobroma cacao	41.54	2.00e-50	192.00
IUUC-Tbe-128116	Tupaia belangeri	98.14	5.00e-93	333.00
IUUC-Ttr-128622	Tursiops truncatus	98.52	9.00e-151	525.00
IUUC-Vvi-131389	Vitis vinifera	43.75	5.00e-53	201.00
IUUC-Xma-134191	Xiphophorus maculatus	81.67	2.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence