iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074025

Ensembl Protein ID

ENSOCUP00000002471.3

UniProt Accession

G1SIG2; G1SIG2_RABIT

Genbank Protein ID

ENSOCUP00000002471

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02049767

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002844.3	ENSOCUT00000002846.3	ENSOCUP00000002471.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-13	50.1	134	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 134  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 189
           689*************************..6999******9.5**************98 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVTLLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY 60
IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCACCTCT TCTGGGAAGC CCTCTTGGAT TCCCTCATAG TCTGGCTAAG GAGACTGCTC 60
TGGGTCTTTG TCATTTTCCT CACACCTGTG TCAGGGGCCG TCTCCTGGTT CCTCCTACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	98.48	8.00e-96	343.00
IUUC-Bta-012320	Bos taurus	99.01	4.00e-99	354.00
IUUC-Cja-019935	Callithrix jacchus	93.60	2.00e-103	368.00
IUUC-Cfa-021221	Canis familiaris	98.52	4.00e-99	354.00
IUUC-Cpo-021592	Cavia porcellus	78.97	7.00e-75	273.00
IUUC-Csa-024128	Chlorocebus sabaeus	99.02	5.00e-100	356.00
IUUC-Dno-029847	Dasypus novemcinctus	99.01	4.00e-99	354.00
IUUC-Dor-030360	Dipodomys ordii	84.24	4.00e-94	337.00
IUUC-Eca-033233	Equus caballus	96.55	2.00e-98	351.00
IUUC-Ggo-045475	Gorilla gorilla	99.01	4.00e-99	354.00
IUUC-Hsa-046008	Homo sapiens	99.01	4.00e-99	354.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	98.53	5.00e-98	350.00
IUUC-Loc-052229	Lepisosteus oculatus	68.75	1.00e-82	299.00
IUUC-Laf-053896	Loxodonta africana	91.75	1.00e-102	365.00
IUUC-Mcc-055280	Macaca mulatta	99.01	4.00e-99	354.00
IUUC-Mmu-063691	Mus musculus	98.52	8.00e-99	353.00
IUUC-Mpu-065737	Mustela putorius furo	98.52	4.00e-99	354.00
IUUC-Opr-071114	Ochotona princeps	97.04	6.00e-103	367.00
IUUC-Oan-072967	Ornithorhynchus anatinus	91.63	7.00e-98	350.00
IUUC-Oga-088266	Otolemur garnettii	97.04	3.00e-98	350.00
IUUC-Oar-089221	Ovis aries	96.57	1.00e-94	339.00
IUUC-Ptr-091463	Pan troglodytes	92.12	2.00e-87	315.00
IUUC-Pan-092242	Papio anubis	98.52	4.00e-99	354.00
IUUC-Pab-097823	Pongo abelii	99.02	5.00e-100	356.00
IUUC-Pca-101068	Procavia capensis	99.01	4.00e-99	354.00
IUUC-Rno-105288	Rattus norvegicus	99.01	4.00e-99	354.00
IUUC-Sar-113453	Sorex araneus	76.35	3.00e-83	301.00
IUUC-Tbe-127436	Tupaia belangeri	97.98	3.00e-94	338.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence