iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088007

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03039444

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000010047.2	ENSOGAT00000010054.2	ENSOGAP00000008979.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-65	221.8	179	453

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 52   slqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknk 139
           ++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy+qqDaqEfl+ l+++l+ e+++    +  ++     +      +++     +
   Q: 179  AFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINR----RGRRAPPILANGPAPAPPRRGGALLE 263
           6789999999878889*****************************************66....44555555555666777888889999 PP
   S: 140  slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklP 227
           ++  dlF gqlks +kc++c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P
   Q: 264  EPELDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFP 352
           9*************************************887541456****************************************** PP
   S: 228  evLilh.LkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskV 314
           ++L+lh L+Rf  s +++s +k +  v+fpl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V
   Q: 353  RILVLHnLNRF--SASRGSIKKSSVGVDFPLQrLSLGDFASDKAG----SPVYQLYALCNHSGSVHYGHYTALCRC-QSGWHVYNDSRV 434
           *****989***..56668999**********99*******99543....78*************************.777********* PP
   S: 315  tevkeeevleetgstaYvlfYk 336
           ++v+e++v +   s++YvlfY+
   Q: 435  SPVSENQVAS---SEGYVLFYQ 453
           **********...********8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MPQASEHRLS RTREPPVNVQ PRVGSKLPFA PRARSKERRX RADHGVPLPG SPPPAVALPL 60
PSRSNLARSK SVSSGDLRPM GIALGGHRGT GELGAALSRL ALRPEPPTLR RSTSLRRLGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCAGG CTTCTGAGCA CCGCCTGAGC CGGACCCGAG AGCCACCTGT TAATGTCCAG 60
CCCCGAGTGG GATCAAAACT ACCATTTGCT CCAAGGGCCC GCAGCAAGGA ACGCCGCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	78.62	0.00e+00	803.00
IUUC-Aca-004612	Anolis carolinensis	56.51	7.00e-134	470.00
IUUC-Bta-012626	Bos taurus	78.27	0.00e+00	775.00
IUUC-Cja-018853	Callithrix jacchus	78.62	0.00e+00	806.00
IUUC-Cfa-021167	Canis familiaris	79.15	0.00e+00	786.00
IUUC-Cpo-021305	Cavia porcellus	78.13	0.00e+00	743.00
IUUC-Csa-023454	Chlorocebus sabaeus	79.15	0.00e+00	813.00
IUUC-Cho-024836	Choloepus hoffmanni	95.36	1.00e-106	379.00
IUUC-Dre-028454	Danio rerio	46.36	4.00e-82	298.00
IUUC-Dno-029955	Dasypus novemcinctus	71.35	5.00e-118	418.00
IUUC-Dor-031053	Dipodomys ordii	78.80	0.00e+00	809.00
IUUC-Ete-032416	Echinops telfairi	87.31	2.00e-125	442.00
IUUC-Eca-033817	Equus caballus	77.56	0.00e+00	801.00
IUUC-Fca-036400	Felis catus	76.58	0.00e+00	775.00
IUUC-Ggo-045174	Gorilla gorilla	79.15	0.00e+00	813.00
IUUC-Hsa-046443	Homo sapiens	79.15	0.00e+00	813.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	78.38	0.00e+00	806.00
IUUC-Lch-050539	Latimeria chalumnae	56.52	2.00e-90	326.00
IUUC-Laf-053730	Loxodonta africana	76.76	0.00e+00	783.00
IUUC-Mcc-055541	Macaca mulatta	79.15	0.00e+00	813.00
IUUC-Meu-056279	Macropus eugenii	72.84	0.00e+00	732.00
IUUC-Mmr-060913	Microcebus murinus	79.86	0.00e+00	769.00
IUUC-Mdo-061807	Monodelphis domestica	73.90	0.00e+00	728.00
IUUC-Mmu-063599	Mus musculus	78.07	0.00e+00	777.00
IUUC-Mpu-066329	Mustela putorius furo	79.15	0.00e+00	788.00
IUUC-Mlu-067359	Myotis lucifugus	76.00	0.00e+00	672.00
IUUC-Nle-070084	Nomascus leucogenys	76.33	0.00e+00	756.00
IUUC-Opr-071096	Ochotona princeps	75.93	0.00e+00	756.00
IUUC-Ocu-074228	Oryctolagus cuniculus	78.38	0.00e+00	780.00
IUUC-Oar-090226	Ovis aries	72.75	1.00e-163	569.00
IUUC-Ptr-091522	Pan troglodytes	79.15	0.00e+00	813.00
IUUC-Pan-091954	Papio anubis	78.80	0.00e+00	806.00
IUUC-Psi-093216	Pelodiscus sinensis	50.08	3.00e-145	509.00
IUUC-Pab-098691	Pongo abelii	78.98	0.00e+00	811.00
IUUC-Pca-101133	Procavia capensis	77.56	0.00e+00	795.00
IUUC-Pva-102681	Pteropus vampyrus	73.50	0.00e+00	731.00
IUUC-Rno-105132	Rattus norvegicus	78.45	0.00e+00	778.00
IUUC-Sha-107145	Sarcophilus harrisii	71.93	0.00e+00	679.00
IUUC-Ssc-115586	Sus scrofa	79.33	0.00e+00	768.00
IUUC-Tgu-117491	Taeniopygia guttata	74.36	1.00e-79	288.00
IUUC-Tbe-127465	Tupaia belangeri	97.45	7.00e-112	397.00
IUUC-Ttr-128274	Tursiops truncatus	78.33	0.00e+00	785.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence