iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073501

Ensembl Protein ID

ENSOANP00000010037.1

UniProt Accession

F6VPM6; F6VPM6_ORNAN

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006277.1	ENSOANT00000010039.1	ENSOANP00000010037.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.67	0.00e+00	769.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

GPGADGGRVL DTLSPASSPS SINYPAVPGS SDESCSGMLN IECRICGDKA SGYHYGVHAC 60
EGCKGFFRRT IRLKLAYDKC DRTCKIQKKN RNKCQYCRFQ KCLSVGMSHN AIRFGRMPRS 120

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Nucleotide Sequence
(Fasta)

GGACCCGGAG CGGACGGGGG TCGGGTAATA ATAATGTTGG TATTTGTTAA GCGCTTACTA 60
TGTGCCGAGC ACTGTTCTAA GCGCTGGGGT AGACATAGGG GAACCAGGTT GTCCCACGTG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	89.29	0.00e+00	757.00
IUUC-Apl-003330	Anas platyrhynchos	89.35	0.00e+00	752.00
IUUC-Aca-004598	Anolis carolinensis	88.02	0.00e+00	722.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.40e-01	28.90
IUUC-Ame-011508	Astyanax mexicanus	79.90	0.00e+00	639.00
IUUC-Bta-012621	Bos taurus	92.42	0.00e+00	734.00
IUUC-Cja-019688	Callithrix jacchus	90.71	0.00e+00	726.00
IUUC-Cfa-020859	Canis familiaris	90.22	0.00e+00	757.00
IUUC-Cpo-021607	Cavia porcellus	84.60	0.00e+00	676.00
IUUC-Csa-023313	Chlorocebus sabaeus	90.93	0.00e+00	723.00
IUUC-Cho-024741	Choloepus hoffmanni	92.17	0.00e+00	644.00
IUUC-Dre-027446	Danio rerio	76.40	0.00e+00	625.00
IUUC-Dno-029173	Dasypus novemcinctus	89.24	0.00e+00	748.00
IUUC-Dor-030581	Dipodomys ordii	88.26	0.00e+00	709.00
IUUC-Dme-031794	Drosophila melanogaster	32.90	7.00e-50	192.00
IUUC-Ete-032330	Echinops telfairi	88.26	0.00e+00	738.00
IUUC-Eca-033712	Equus caballus	91.44	0.00e+00	722.00
IUUC-Fca-036555	Felis catus	90.02	0.00e+00	758.00
IUUC-Fal-036677	Ficedula albicollis	90.71	0.00e+00	754.00
IUUC-Gmo-039240	Gadus morhua	81.23	8.00e-177	612.00
IUUC-Gga-040473	Gallus gallus	91.20	0.00e+00	758.00
IUUC-Gac-041872	Gasterosteus aculeatus	76.34	0.00e+00	639.00
IUUC-Ggo-045226	Gorilla gorilla	91.67	0.00e+00	731.00
IUUC-Hsa-046893	Homo sapiens	91.67	0.00e+00	731.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	89.24	0.00e+00	711.00
IUUC-Lch-050116	Latimeria chalumnae	81.66	0.00e+00	692.00
IUUC-Loc-052131	Lepisosteus oculatus	82.25	0.00e+00	657.00
IUUC-Laf-054323	Loxodonta africana	91.20	0.00e+00	729.00
IUUC-Mcc-054841	Macaca mulatta	91.42	0.00e+00	726.00
IUUC-Meu-056833	Macropus eugenii	93.62	0.00e+00	658.00
IUUC-Mga-059995	Meleagris gallopavo	79.42	0.00e+00	656.00
IUUC-Mmr-060576	Microcebus murinus	64.12	2.00e-139	488.00
IUUC-Mdo-061954	Monodelphis domestica	90.44	0.00e+00	719.00
IUUC-Mmu-064295	Mus musculus	87.01	0.00e+00	704.00
IUUC-Mpu-066216	Mustela putorius furo	90.95	0.00e+00	763.00
IUUC-Mlu-067978	Myotis lucifugus	63.85	8.00e-144	503.00
IUUC-Nle-069970	Nomascus leucogenys	91.67	0.00e+00	731.00
IUUC-Opr-070630	Ochotona princeps	63.69	8.00e-118	416.00
IUUC-Ont-071594	Oreochromis niloticus	77.07	0.00e+00	630.00
IUUC-Ocu-074634	Oryctolagus cuniculus	80.54	0.00e+00	680.00
IUUC-Oni-082926	Oryza nivara	30.19	1.70e-02	29.60
IUUC-Ola-086585	Oryzias latipes	79.37	2.00e-176	610.00
IUUC-Oga-088738	Otolemur garnettii	91.20	0.00e+00	721.00
IUUC-Oar-090453	Ovis aries	92.18	0.00e+00	733.00
IUUC-Ptr-091518	Pan troglodytes	91.42	0.00e+00	724.00
IUUC-Pan-092006	Papio anubis	91.42	0.00e+00	725.00
IUUC-Psi-093352	Pelodiscus sinensis	89.10	0.00e+00	754.00
IUUC-Pfo-096060	Poecilia formosa	76.10	0.00e+00	628.00
IUUC-Pab-098602	Pongo abelii	85.02	0.00e+00	634.00
IUUC-Pca-100861	Procavia capensis	64.38	4.00e-138	484.00
IUUC-Pva-102175	Pteropus vampyrus	85.33	0.00e+00	704.00
IUUC-Rno-105283	Rattus norvegicus	88.24	0.00e+00	708.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	2.80e-02	29.60
IUUC-Sha-106560	Sarcophilus harrisii	91.44	0.00e+00	768.00
IUUC-Smo-109075	Selaginella moellendorffii	28.57	5.00e-01	26.90
IUUC-Sar-112996	Sorex araneus	52.76	4.00e-104	371.00
IUUC-Ssc-115266	Sus scrofa	90.22	0.00e+00	759.00
IUUC-Tgu-116778	Taeniopygia guttata	90.46	0.00e+00	754.00
IUUC-Tru-118436	Takifugu rubripes	76.34	0.00e+00	636.00
IUUC-Tsy-119642	Tarsius syrichta	76.53	3.00e-167	580.00
IUUC-Tni-119859	Tetraodon nigroviridis	76.83	0.00e+00	634.00
IUUC-Tvi-122624	Trichoderma virens	30.00	7.40e-01	25.80
IUUC-Tbe-127464	Tupaia belangeri	89.73	0.00e+00	747.00
IUUC-Ttr-129307	Tursiops truncatus	87.56	0.00e+00	678.00
IUUC-Vpa-130378	Vicugna pacos	64.16	2.00e-113	401.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence