iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089360

Ensembl Protein ID

ENSOARP00000022245.1

UniProt Accession

W5QHP5; W5QHP5_SHEEP

Genbank Protein ID

ENSOARP00000022245

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01009499

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020697.1	ENSOART00000022550.1	ENSOARP00000022245.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.90e-39	130.4	224	258
UBD/Beta-Prp	7.40e-52	176.5	47	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 224  GHLSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 258
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++     
   Q: 47   TRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRv 135
           56899*****************************************************************************9877766 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + ++ +v++s D+t+ lWd++t++  +t+tg h ++v sls++++++ +vsg++d + klwd++ g c +++
   Q: 136  srELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTTFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSF 222
           779*************99.67789***********************9.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           +gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++ 
   Q: 223  TGHLSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD 267
           *************************************99888874 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCAAGCTG AGGCCTGCGC GGTGGCAGGA AGGAAACTGG CCACATCACT TGGGCGCTCC 60
TCAGAAGTGT GCTTCGGAGT CCAGGCGCCT CACCAAGAAA ACGAAACTGC CCGGGGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

KEGG

oas:101108976

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	99.38	0.00e+00	665.00
IUUC-Apl-003923	Anas platyrhynchos	94.44	2.00e-175	607.00
IUUC-Aca-004754	Anolis carolinensis	94.43	5.00e-176	609.00
IUUC-Ago-007831	Ashbya gossypii	37.73	5.00e-65	241.00
IUUC-Acl-008154	Aspergillus clavatus	66.47	7.00e-137	480.00
IUUC-Afl-008568	Aspergillus flavus	66.47	2.00e-138	485.00
IUUC-Afu-008789	Aspergillus fumigatus	66.47	7.00e-137	480.00
IUUC-Ani-009213	Aspergillus nidulans	65.88	2.00e-136	478.00
IUUC-Aor-010165	Aspergillus oryzae	66.47	2.00e-138	485.00
IUUC-Ate-010520	Aspergillus terreus	61.76	5.00e-110	390.00
IUUC-Ame-011092	Astyanax mexicanus	90.88	0.00e+00	650.00
IUUC-Bta-013200	Bos taurus	99.38	0.00e+00	663.00
IUUC-Cel-018704	Caenorhabditis elegans	84.71	1.00e-178	618.00
IUUC-Cja-019845	Callithrix jacchus	99.38	0.00e+00	664.00
IUUC-Cfa-020395	Canis familiaris	99.38	0.00e+00	665.00
IUUC-Cpo-021376	Cavia porcellus	98.76	0.00e+00	664.00
IUUC-Csa-023295	Chlorocebus sabaeus	99.69	0.00e+00	666.00
IUUC-Cho-024766	Choloepus hoffmanni	99.08	0.00e+00	667.00
IUUC-Cin-025309	Ciona intestinalis	78.70	7.00e-169	586.00
IUUC-Csv-026258	Ciona savignyi	78.40	6.00e-168	583.00
IUUC-Dre-027412	Danio rerio	91.18	0.00e+00	650.00
IUUC-Dno-029802	Dasypus novemcinctus	99.01	0.00e+00	626.00
IUUC-Dor-030322	Dipodomys ordii	80.19	7.00e-154	536.00
IUUC-Dse-031388	Dothistroma septosporum	66.76	3.00e-137	481.00
IUUC-Dme-031748	Drosophila melanogaster	81.47	8.00e-173	599.00
IUUC-Ete-032710	Echinops telfairi	96.43	2.00e-179	621.00
IUUC-Eca-033628	Equus caballus	99.07	0.00e+00	663.00
IUUC-Eeu-034978	Erinaceus europaeus	97.07	3.00e-157	547.00
IUUC-Fal-037616	Ficedula albicollis	94.74	1.00e-176	612.00
IUUC-Gmo-039556	Gadus morhua	92.26	2.00e-180	624.00
IUUC-Gga-040249	Gallus gallus	94.74	1.00e-176	612.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.33	2.00e-180	624.00
IUUC-Ggo-044954	Gorilla gorilla	99.38	0.00e+00	664.00
IUUC-Hsa-046105	Homo sapiens	99.69	0.00e+00	666.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	99.69	0.00e+00	663.00
IUUC-Kpa-049192	Komagataella pastoris	38.89	1.00e-62	233.00
IUUC-Lch-049422	Latimeria chalumnae	91.76	0.00e+00	626.00
IUUC-Loc-052939	Lepisosteus oculatus	91.47	0.00e+00	652.00
IUUC-Mcc-055787	Macaca mulatta	99.69	0.00e+00	666.00
IUUC-Meu-056902	Macropus eugenii	89.47	1.00e-176	612.00
IUUC-Mla-059086	Melampsora laricipopulina	70.33	3.00e-147	514.00
IUUC-Mga-060050	Meleagris gallopavo	94.44	2.00e-175	607.00
IUUC-Mvi-060482	Microbotryum violaceum	68.55	3.00e-145	507.00
IUUC-Mmr-060931	Microcebus murinus	99.69	0.00e+00	666.00
IUUC-Mdo-063055	Monodelphis domestica	94.12	8.00e-176	609.00
IUUC-Mmu-064368	Mus musculus	96.59	0.00e+00	650.00
IUUC-Mpu-066358	Mustela putorius furo	99.38	0.00e+00	665.00
IUUC-Mlu-067328	Myotis lucifugus	98.45	0.00e+00	659.00
IUUC-Nfi-068332	Neosartorya fischeri	66.47	2.00e-136	478.00
IUUC-Nle-069612	Nomascus leucogenys	99.69	0.00e+00	666.00
IUUC-Ont-071287	Oreochromis niloticus	92.26	2.00e-180	624.00
IUUC-Oan-072913	Ornithorhynchus anatinus	95.05	1.00e-177	615.00
IUUC-Ocu-074126	Oryctolagus cuniculus	99.07	0.00e+00	668.00
IUUC-Ola-087297	Oryzias latipes	92.00	0.00e+00	627.00
IUUC-Ptr-091437	Pan troglodytes	99.69	0.00e+00	666.00
IUUC-Pan-092195	Papio anubis	99.38	0.00e+00	664.00
IUUC-Psi-093718	Pelodiscus sinensis	94.74	1.00e-176	612.00
IUUC-Pma-094748	Petromyzon marinus	88.49	2.00e-136	478.00
IUUC-Pfo-096251	Poecilia formosa	91.95	7.00e-180	622.00
IUUC-Pgr-103321	Puccinia graminis	70.62	2.00e-148	518.00
IUUC-Ptt-103728	Puccinia triticina	70.62	2.00e-148	518.00
IUUC-Sce-106298	Saccharomyces cerevisiae	37.40	2.00e-68	252.00
IUUC-Sha-106534	Sarcophilus harrisii	94.12	3.00e-176	610.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.48	9.00e-60	223.00
IUUC-Spo-108352	Schizosaccharomyces pombe	41.69	1.00e-69	256.00
IUUC-Smo-108835	Selaginella moellendorffii	43.58	3.00e-74	271.00
IUUC-Sar-113642	Sorex araneus	98.90	8.00e-161	559.00
IUUC-Tgu-117198	Taeniopygia guttata	94.74	1.00e-176	612.00
IUUC-Tru-118399	Takifugu rubripes	91.64	3.00e-180	624.00
IUUC-Tsy-119354	Tarsius syrichta	96.28	0.00e+00	647.00
IUUC-Tni-120495	Tetraodon nigroviridis	90.88	0.00e+00	643.00
IUUC-Tme-126886	Tuber melanosporum	67.96	2.00e-134	471.00
IUUC-Tbe-128132	Tupaia belangeri	89.45	9.00e-137	478.00
IUUC-Ttr-129243	Tursiops truncatus	99.69	0.00e+00	666.00
IUUC-Vda-129855	Verticillium dahliae	71.04	3.00e-128	451.00
IUUC-Xtr-131924	Xenopus tropicalis	94.74	2.00e-176	611.00
IUUC-Xma-133743	Xiphophorus maculatus	92.06	0.00e+00	655.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence