iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-092963

Ensembl Protein ID

ENSPSIP00000018157.1

UniProt Accession

K7GCZ6; K7GCZ6_PELSI

Genbank Protein ID

ENSPSIP00000018157

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01048609

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000016059.1	ENSPSIT00000018242.1	ENSPSIP00000018157.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.00e-103	345.0	459	797

Active Site

Position(s)	Description	Evidence
765	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G l+g+a++++  ld+
   Q: 459  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSYKC-----DNYSEFRLVGALMGLAVYNSITLDI 542
           589**************************************************976655.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++ledl +++pel++ l e++++ e+++ee ++  tf+v +e++g +k+++LkpgG++ipV
   Q: 543  RFPPCCYKKLLSPpivpcdqntpvgnsNVTLEDLCQIMPELAHGLSELLSY-EDNVEE-DFYSTFQVFQEEFGVIKSYNLKPGGDKIPV 629
           **********999666666666666666**********************9.556666.6***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l+v+++l+++i +q+++f+ Gf++v++   l l+++ee+e+l+cG++e+d+ +l+++t+y+g y +++ +i++Fw+v+ 
   Q: 630  TNQNRKEYVQLYVDFILNKSIYKQFAEFYYGFHSVCDSYALMLLRPEEVEILVCGSPELDMYALQRNTQYDG-YLKTDLTIRYFWDVVL 717
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y++k++lk+kL++ i++++gF+l+
   Q: 718  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKsETSTNWLPVAHTCFNQLCLPPYKNKKELKQKLIIGISNAEGFGLE 797
           *****************************...9999967777**************************************985 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MSLQIPQAAT TGSDLPAVTE KGSLLGYKMS EDSCVPSSVE EEEEDGEKEK EREKLPPILT 60
SSNTAAGGFE RGDKSQFSTF SSFISTINQK KEASESSNSP TQLVIPNIKN VRDLPPLCLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCACTGC AGATCCCGCA GGCTGCCACA ACCGGCTCAG ATCTCCCCGC TGTTACCGAG 60
AAAGGGTCCT TGCTGGGTTA CAAAATGAGC GAGGACAGTT GTGTTCCCTC GTCAGTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

pss:102445555

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	87.19	0.00e+00	1347.00
IUUC-Apl-003589	Anas platyrhynchos	89.47	0.00e+00	1348.00
IUUC-Aca-004350	Anolis carolinensis	83.79	0.00e+00	1261.00
IUUC-Ago-007908	Ashbya gossypii	34.00	2.00e-78	287.00
IUUC-Acl-008288	Aspergillus clavatus	34.87	9.00e-96	345.00
IUUC-Afl-008402	Aspergillus flavus	33.50	4.00e-89	322.00
IUUC-Afu-008762	Aspergillus fumigatus	34.48	2.00e-94	340.00
IUUC-Ani-009176	Aspergillus nidulans	34.39	2.00e-90	327.00
IUUC-Ang-009791	Aspergillus niger	34.58	4.00e-90	326.00
IUUC-Aor-009921	Aspergillus oryzae	33.33	1.00e-88	320.00
IUUC-Ate-010295	Aspergillus terreus	34.83	8.00e-98	352.00
IUUC-Ame-010660	Astyanax mexicanus	82.27	7.00e-152	529.00
IUUC-Bgr-011981	Blumeria graminis	32.90	3.00e-89	323.00
IUUC-Bta-012945	Bos taurus	86.35	0.00e+00	1323.00
IUUC-Bci-013697	Botrytis cinerea	38.56	3.00e-80	293.00
IUUC-Cja-019263	Callithrix jacchus	84.81	0.00e+00	1298.00
IUUC-Cfa-020486	Canis familiaris	90.08	0.00e+00	1230.00
IUUC-Cpo-021755	Cavia porcellus	84.91	0.00e+00	1320.00
IUUC-Csa-023814	Chlorocebus sabaeus	84.88	0.00e+00	1233.00
IUUC-Cho-024980	Choloepus hoffmanni	70.27	0.00e+00	1033.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.61	8.00e-96	345.00
IUUC-Dre-028551	Danio rerio	76.21	0.00e+00	1168.00
IUUC-Dno-029497	Dasypus novemcinctus	85.51	0.00e+00	1196.00
IUUC-Dor-030867	Dipodomys ordii	74.90	0.00e+00	1094.00
IUUC-Dse-031239	Dothistroma septosporum	31.21	3.00e-85	310.00
IUUC-Ete-032902	Echinops telfairi	71.76	0.00e+00	1086.00
IUUC-Eca-033678	Equus caballus	86.44	0.00e+00	1316.00
IUUC-Eeu-035262	Erinaceus europaeus	72.59	0.00e+00	997.00
IUUC-Fca-035590	Felis catus	87.53	0.00e+00	1349.00
IUUC-Fal-037123	Ficedula albicollis	85.70	0.00e+00	1300.00
IUUC-Fox-037941	Fusarium oxysporum	38.45	4.00e-101	363.00
IUUC-Fso-038388	Fusarium solani	41.27	7.00e-103	369.00
IUUC-Gmo-039553	Gadus morhua	65.52	0.00e+00	847.00
IUUC-Ggr-040110	Gaeumannomyces graminis	39.68	2.00e-96	347.00
IUUC-Gga-040406	Gallus gallus	89.54	0.00e+00	1390.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.80	0.00e+00	1116.00
IUUC-Ggo-045504	Gorilla gorilla	84.47	0.00e+00	1304.00
IUUC-Hsa-045786	Homo sapiens	84.93	0.00e+00	1310.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	82.70	0.00e+00	1159.00
IUUC-Kpa-049152	Komagataella pastoris	32.80	2.00e-78	287.00
IUUC-Lch-049824	Latimeria chalumnae	82.49	0.00e+00	1133.00
IUUC-Loc-052173	Lepisosteus oculatus	80.24	0.00e+00	1219.00
IUUC-Laf-054017	Loxodonta africana	87.92	0.00e+00	1263.00
IUUC-Mcc-055713	Macaca mulatta	84.95	0.00e+00	1283.00
IUUC-Meu-056212	Macropus eugenii	68.83	3.00e-113	402.00
IUUC-Mor-057045	Magnaporthe oryzae	38.19	1.00e-90	328.00
IUUC-Mla-059187	Melampsora laricipopulina	43.19	1.00e-87	316.00
IUUC-Mga-059884	Meleagris gallopavo	81.47	0.00e+00	1211.00
IUUC-Mmr-061344	Microcebus murinus	86.15	0.00e+00	1303.00
IUUC-Mdo-062653	Monodelphis domestica	86.25	0.00e+00	1313.00
IUUC-Mmu-063775	Mus musculus	84.33	0.00e+00	1225.00
IUUC-Mpu-066069	Mustela putorius furo	88.82	0.00e+00	1241.00
IUUC-Mlu-067925	Myotis lucifugus	86.16	0.00e+00	1295.00
IUUC-Nfi-068439	Neosartorya fischeri	33.83	7.00e-93	335.00
IUUC-Ncr-068903	Neurospora crassa	37.07	2.00e-91	331.00
IUUC-Nle-070046	Nomascus leucogenys	84.87	0.00e+00	1314.00
IUUC-Opr-071085	Ochotona princeps	73.83	5.00e-127	448.00
IUUC-Ont-072126	Oreochromis niloticus	73.49	0.00e+00	1172.00
IUUC-Oan-072933	Ornithorhynchus anatinus	87.19	0.00e+00	1166.00
IUUC-Ocu-073800	Oryctolagus cuniculus	88.67	0.00e+00	1224.00
IUUC-Ola-086988	Oryzias latipes	76.27	0.00e+00	1126.00
IUUC-Oga-088117	Otolemur garnettii	89.14	0.00e+00	1075.00
IUUC-Oar-089371	Ovis aries	87.26	0.00e+00	1299.00
IUUC-Ptr-090551	Pan troglodytes	83.80	0.00e+00	1266.00
IUUC-Pan-092067	Papio anubis	85.41	0.00e+00	1288.00
IUUC-Pfo-096562	Poecilia formosa	70.45	0.00e+00	1122.00
IUUC-Pab-098680	Pongo abelii	85.06	0.00e+00	1310.00
IUUC-Pca-100986	Procavia capensis	71.17	0.00e+00	855.00
IUUC-Pva-102219	Pteropus vampyrus	72.14	0.00e+00	990.00
IUUC-Pgr-103315	Puccinia graminis	35.70	3.00e-94	339.00
IUUC-Ptt-103736	Puccinia triticina	41.06	6.00e-94	338.00
IUUC-Rno-105270	Rattus norvegicus	83.88	0.00e+00	1230.00
IUUC-Sce-106306	Saccharomyces cerevisiae	35.04	8.00e-73	268.00
IUUC-Sha-106819	Sarcophilus harrisii	87.11	0.00e+00	1337.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.27	4.00e-83	302.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	38.56	2.00e-82	300.00
IUUC-Sar-113134	Sorex araneus	77.95	0.00e+00	1147.00
IUUC-Ssc-115441	Sus scrofa	86.37	0.00e+00	1309.00
IUUC-Tgu-117166	Taeniopygia guttata	87.21	0.00e+00	1306.00
IUUC-Tsy-118898	Tarsius syrichta	74.35	0.00e+00	1039.00
IUUC-Tre-122108	Trichoderma reesei	37.60	6.00e-89	322.00
IUUC-Tvi-122644	Trichoderma virens	37.88	1.00e-93	338.00
IUUC-Tme-127004	Tuber melanosporum	34.10	8.00e-101	362.00
IUUC-Tbe-127292	Tupaia belangeri	71.37	0.00e+00	995.00
IUUC-Ttr-128352	Tursiops truncatus	83.56	0.00e+00	1253.00
IUUC-Vda-129969	Verticillium dahliae	40.26	7.00e-92	332.00
IUUC-Vpa-130218	Vicugna pacos	84.60	0.00e+00	939.00
IUUC-Xtr-132594	Xenopus tropicalis	79.54	0.00e+00	1197.00
IUUC-Xma-134157	Xiphophorus maculatus	73.77	0.00e+00	1035.00
IUUC-Yli-134470	Yarrowia lipolytica	34.68	1.00e-78	287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence