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Tag Content
iUUCD ID IUUC-Tgu-116585
Ensembl Protein ID ENSTGUP00000004946.1
UniProt Accession H0Z304; H0Z304_TAEGU
Genbank Protein ID ENSTGUP00000004946
Protein Name Phosphoinositide phospholipase C
Genbank Nucleotide ID ABQF01028635
Gene Name PLCG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTGUG00000004737.1 ENSTGUT00000004995.1 ENSTGUP00000004946.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.60e-12 46.4 778 836
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekle 63
           +k  v++l+dy+aq +deLt++k  +++ +  e+q++gW++g  +  gk+ l fP+n+ve++ 
   Q: 778  FKCAVKALFDYKAQREDELTFTKNAIIQNV--EKQEGGWWRG--DYGGKKQLwFPSNYVEEIT 836
           56789************************9..9*********..676666655*******985 PP
   
Organism Taeniopygia guttata
Protein Sequence
(Fasta)
GPGAPSEAEA AQLCRSLEVG TVMTLFYSKK SQRPERKTFQ VKLETRQVTW SRGSEKVEGA 60
VDIREIKEIR PGRNSRDFDR YQEDPCFRPD HSHCFVVLYG TEFRLKTLSL QATSEDEVNM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tgu-116585|UBD,SH3|Taeniopygia guttata
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCCCGGGG CGCCCAGCGA GGCGGAGGCG GCGCAGCTCT GCCGCAGCTT GGAGGTGGGC 60
ACCGTCATGA CCCTCTTCTA CTCCAAAAAG TCGCAGCGAC CCGAGCGGAA AACTTTCCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tgu-116585|UBD,SH3|Taeniopygia guttata
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0019722--P:calcium-mediated signaling
GO:0016477--P:cell migration
GO:0071364--P:cellular response to epidermal growth factor stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0009395--P:phospholipid catabolic process
GO:0045766--P:positive regulation of angiogenesis
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0051281--P:positive regulation of release of sequestered calcium ion into cytosol
GO:0050852--P:T cell receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 85.83 0.00e+00 2252.00
IUUC-Aca-005291 Anolis carolinensis 86.25 0.00e+00 2216.00
IUUC-Ame-011004 Astyanax mexicanus 66.44 0.00e+00 1703.00
IUUC-Bta-012660 Bos taurus 85.73 0.00e+00 2138.00
IUUC-Cja-019206 Callithrix jacchus 85.47 0.00e+00 2234.00
IUUC-Cfa-020257 Canis familiaris 85.89 0.00e+00 2144.00
IUUC-Cpo-022391 Cavia porcellus 80.69 0.00e+00 2081.00
IUUC-Csa-024170 Chlorocebus sabaeus 86.27 0.00e+00 1645.00
IUUC-Cin-025520 Ciona intestinalis 48.11 0.00e+00 1098.00
IUUC-Dre-027944 Danio rerio 69.90 0.00e+00 1792.00
IUUC-Dno-029440 Dasypus novemcinctus 84.82 0.00e+00 2039.00
IUUC-Dor-031001 Dipodomys ordii 84.92 0.00e+00 2229.00
IUUC-Eca-033809 Equus caballus 85.89 0.00e+00 2147.00
IUUC-Fca-036510 Felis catus 85.97 0.00e+00 2150.00
IUUC-Fal-037541 Ficedula albicollis 95.52 0.00e+00 2240.00
IUUC-Gmo-038630 Gadus morhua 65.64 0.00e+00 1415.00
IUUC-Gga-040142 Gallus gallus 94.16 0.00e+00 2391.00
IUUC-Ggo-045063 Gorilla gorilla 85.93 0.00e+00 2258.00
IUUC-Hsa-046428 Homo sapiens 85.85 0.00e+00 2255.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 85.36 0.00e+00 2201.00
IUUC-Lch-049766 Latimeria chalumnae 79.34 0.00e+00 1913.00
IUUC-Loc-052285 Lepisosteus oculatus 75.35 0.00e+00 1955.00
IUUC-Laf-053365 Loxodonta africana 84.93 0.00e+00 2118.00
IUUC-Mcc-054871 Macaca mulatta 85.46 0.00e+00 2236.00
IUUC-Meu-056724 Macropus eugenii 81.56 0.00e+00 1984.00
IUUC-Mga-059329 Meleagris gallopavo 92.82 0.00e+00 2255.00
IUUC-Mmr-061110 Microcebus murinus 85.30 0.00e+00 2229.00
IUUC-Mdo-062448 Monodelphis domestica 86.32 0.00e+00 2261.00
IUUC-Mmu-063565 Mus musculus 85.74 0.00e+00 2242.00
IUUC-Mpu-066683 Mustela putorius furo 85.69 0.00e+00 2251.00
IUUC-Mlu-067779 Myotis lucifugus 85.32 0.00e+00 2129.00
IUUC-Nle-069219 Nomascus leucogenys 86.74 0.00e+00 1891.00
IUUC-Opr-070766 Ochotona princeps 83.95 0.00e+00 1298.00
IUUC-Ont-072524 Oreochromis niloticus 72.45 0.00e+00 1886.00
IUUC-Oan-073214 Ornithorhynchus anatinus 91.30 4.00e-46 176.00
IUUC-Ocu-074361 Oryctolagus cuniculus 84.14 0.00e+00 2190.00
IUUC-Ola-086820 Oryzias latipes 70.79 0.00e+00 1882.00
IUUC-Oga-088172 Otolemur garnettii 85.93 0.00e+00 2251.00
IUUC-Oar-090306 Ovis aries 83.03 0.00e+00 2061.00
IUUC-Ptr-090682 Pan troglodytes 85.85 0.00e+00 2258.00
IUUC-Pan-092835 Papio anubis 88.33 0.00e+00 1654.00
IUUC-Psi-093344 Pelodiscus sinensis 87.88 0.00e+00 2280.00
IUUC-Pfo-096984 Poecilia formosa 70.84 0.00e+00 1834.00
IUUC-Pab-097871 Pongo abelii 85.76 0.00e+00 2218.00
IUUC-Pop-099175 Populus trichocarpa 25.00 2.40e-02 32.70
IUUC-Pca-100772 Procavia capensis 79.20 0.00e+00 2043.00
IUUC-Pva-102790 Pteropus vampyrus 85.91 0.00e+00 2205.00
IUUC-Rno-105974 Rattus norvegicus 85.77 0.00e+00 2251.00
IUUC-Sar-112995 Sorex araneus 83.95 0.00e+00 2167.00
IUUC-Ssc-115360 Sus scrofa 85.30 0.00e+00 2237.00
IUUC-Tru-117742 Takifugu rubripes 71.97 0.00e+00 1904.00
IUUC-Tsy-119259 Tarsius syrichta 90.24 0.00e+00 798.00
IUUC-Tni-120833 Tetraodon nigroviridis 65.60 0.00e+00 1640.00
IUUC-Tbe-127504 Tupaia belangeri 75.06 0.00e+00 1242.00
IUUC-Ttr-128650 Tursiops truncatus 84.10 0.00e+00 1109.00
IUUC-Xtr-132862 Xenopus tropicalis 76.27 0.00e+00 1915.00
Created Date 25-Jun-2017

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