iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054653

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03016018

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008756.3	ENSMMUT00000012228.3	ENSMMUP00000011469.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.90e-09	36.8	14	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++C+e f        ++l+CgHvf++dCl k+     ++ +   ++   CP+Cr
   Q: 14   CPVCYEKFrdleG-ASRTLSCGHVFCHDCLVKYllstrVDGQ--VQRILVCPICR 65
           ********55532.3899************999554332222..444445****8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSEGESKDSS GSECPVCYEK FRDLEGASRT LSCGHVFCHD CLVKYLLSTR VDGQVQRILV 60
CPICRYVTFL SKKSSRWPSM LDKSSQTLTV PVALPSVPPL DSLGHTNPLA ASSSAWRPPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGAAG GGGAGAGCAA GGACAGCTCG GGCAGCGAGT GCCCCGTGTG CTACGAGAAG 60
TTCCGGGACC TGGAGGGCGC CAGCCGGACG CTGAGCTGTG GCCATGTGTT CTGCCATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

mcc:717408

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	88.17	3.00e-46	177.00
IUUC-Atr-002488	Amborella trichopoda	31.75	2.00e-06	46.60
IUUC-Apl-003509	Anas platyrhynchos	46.43	6.00e-36	144.00
IUUC-Aca-004916	Anolis carolinensis	40.24	2.00e-22	98.60
IUUC-Bta-013443	Bos taurus	76.54	1.00e-64	238.00
IUUC-Cja-019637	Callithrix jacchus	96.62	5.00e-80	290.00
IUUC-Cfa-020737	Canis familiaris	76.54	6.00e-62	229.00
IUUC-Cpo-022224	Cavia porcellus	81.40	1.00e-63	236.00
IUUC-Csa-024175	Chlorocebus sabaeus	97.77	7.00e-92	329.00
IUUC-Dre-028060	Danio rerio	34.56	2.00e-21	95.50
IUUC-Dno-030024	Dasypus novemcinctus	83.83	7.00e-70	256.00
IUUC-Dor-030936	Dipodomys ordii	77.09	9.00e-69	252.00
IUUC-Eca-033759	Equus caballus	83.33	2.00e-76	278.00
IUUC-Fal-037142	Ficedula albicollis	43.00	2.00e-29	122.00
IUUC-Gmo-039196	Gadus morhua	34.62	8.00e-20	90.10
IUUC-Gga-041189	Gallus gallus	46.39	5.00e-33	133.00
IUUC-Gac-041497	Gasterosteus aculeatus	38.18	1.00e-21	96.30
IUUC-Ggo-045020	Gorilla gorilla	95.15	3.00e-82	297.00
IUUC-Hsa-046317	Homo sapiens	96.36	2.00e-70	258.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	81.01	2.00e-74	271.00
IUUC-Lch-049885	Latimeria chalumnae	38.10	2.00e-22	99.00
IUUC-Laf-053457	Loxodonta africana	78.21	1.00e-71	262.00
IUUC-Mga-059753	Meleagris gallopavo	46.03	4.00e-35	141.00
IUUC-Mdo-062993	Monodelphis domestica	71.49	5.00e-70	256.00
IUUC-Mmu-063225	Mus musculus	79.89	8.00e-66	243.00
IUUC-Mpu-066299	Mustela putorius furo	78.77	1.00e-63	235.00
IUUC-Mlu-066988	Myotis lucifugus	77.90	4.00e-65	240.00
IUUC-Nle-069011	Nomascus leucogenys	96.20	2.00e-79	288.00
IUUC-Opr-070258	Ochotona princeps	84.92	4.00e-71	260.00
IUUC-Ont-071886	Oreochromis niloticus	38.86	3.00e-23	101.00
IUUC-Ocu-074282	Oryctolagus cuniculus	84.36	2.00e-68	251.00
IUUC-Oga-088403	Otolemur garnettii	79.89	1.00e-73	268.00
IUUC-Oar-089665	Ovis aries	81.63	1.00e-19	87.40
IUUC-Ptr-090580	Pan troglodytes	96.97	9.00e-73	266.00
IUUC-Pan-092447	Papio anubis	99.37	6.00e-89	320.00
IUUC-Psi-093673	Pelodiscus sinensis	45.13	3.00e-39	154.00
IUUC-Ppa-095340	Physcomitrella patens	35.14	9.00e-08	50.40
IUUC-Pfo-096933	Poecilia formosa	35.50	1.00e-20	92.80
IUUC-Pab-097867	Pongo abelii	96.84	4.00e-69	253.00
IUUC-Pva-102146	Pteropus vampyrus	83.24	4.00e-73	267.00
IUUC-Rno-105897	Rattus norvegicus	81.01	2.00e-66	244.00
IUUC-Sha-107282	Sarcophilus harrisii	63.64	7.00e-53	199.00
IUUC-Sar-113260	Sorex araneus	82.12	2.00e-76	278.00
IUUC-Ssc-115449	Sus scrofa	77.65	9.00e-52	196.00
IUUC-Tgu-117349	Taeniopygia guttata	41.10	1.00e-27	115.00
IUUC-Xtr-132180	Xenopus tropicalis	38.62	1.00e-23	102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence