iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132180

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

MGC97595 protein; Ring finger protein 222

Genbank Nucleotide ID

AAMC01064946

Gene Name

rnf222; MGC97595

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000025234.2	ENSXETT00000017753.3	ENSXETP00000017753.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.90e-09	35.9	16	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw...pglknssskefrCPlCr 46
           C++C+e +        + l+CgH f++dCl k+     +  s +k+++CPlCr
   Q: 16   CPVCYEQLqtntA--ERRLNCGHSFCHDCLVKYllsAKQEGSVRKNIICPLCR 66
           ********65431..33589**********99999977777899********8 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSNDEGGKET PPGSECPVCY EQLQTNTAER RLNCGHSFCH DCLVKYLLSA KQEGSVRKNI 60
ICPLCRYVTF LSKGGLILPP KSGERRQTLE VPISPSCQRH CESARSPNTV EIPISDTETT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAGATCCT TCCAGGAACA ACTCCACTCA TTTGGGCAGA ACCAGAACCT GCAGGACTGA 60
AGGTAACTTA CTGGGGCAGA ATGGGTGCAA CTCAGCATTA CTGGGTCTGA ATGTAAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

xtr:595023

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	56.41	3.00e-21	93.60
IUUC-Apl-003509	Anas platyrhynchos	39.65	9.00e-27	113.00
IUUC-Aca-004916	Anolis carolinensis	40.00	2.00e-18	85.10
IUUC-Bta-013443	Bos taurus	54.43	2.00e-21	95.50
IUUC-Cja-019637	Callithrix jacchus	40.74	5.00e-23	100.00
IUUC-Cfa-020737	Canis familiaris	38.75	2.00e-21	95.10
IUUC-Cpo-022224	Cavia porcellus	40.00	8.00e-21	93.20
IUUC-Csa-024175	Chlorocebus sabaeus	41.36	3.00e-23	101.00
IUUC-Dre-028060	Danio rerio	33.18	1.00e-19	89.40
IUUC-Dno-030024	Dasypus novemcinctus	36.36	6.00e-22	97.10
IUUC-Dor-030936	Dipodomys ordii	41.98	9.00e-24	103.00
IUUC-Eca-033759	Equus caballus	40.35	3.00e-24	104.00
IUUC-Fal-037142	Ficedula albicollis	39.69	5.00e-25	107.00
IUUC-Gmo-039196	Gadus morhua	34.45	2.00e-19	88.60
IUUC-Gga-041189	Gallus gallus	40.66	5.00e-27	113.00
IUUC-Gac-041497	Gasterosteus aculeatus	36.14	2.00e-19	88.20
IUUC-Ggo-045020	Gorilla gorilla	54.43	3.00e-21	95.10
IUUC-Hsa-046317	Homo sapiens	54.43	3.00e-21	95.10
IUUC-Itr-048656	Ictidomys tridecemlineatus	40.96	4.00e-23	100.00
IUUC-Lch-049885	Latimeria chalumnae	40.25	3.00e-26	111.00
IUUC-Laf-053457	Loxodonta africana	40.99	6.00e-25	107.00
IUUC-Mcc-054653	Macaca mulatta	40.74	1.00e-22	99.40
IUUC-Mga-059753	Meleagris gallopavo	42.50	6.00e-26	110.00
IUUC-Mdo-062993	Monodelphis domestica	37.22	6.00e-24	103.00
IUUC-Mmu-063225	Mus musculus	42.24	1.00e-22	99.40
IUUC-Mpu-066299	Mustela putorius furo	38.12	3.00e-22	97.80
IUUC-Mlu-066988	Myotis lucifugus	56.41	4.00e-21	94.40
IUUC-Nle-069011	Nomascus leucogenys	40.12	7.00e-22	97.10
IUUC-Opr-070258	Ochotona princeps	40.74	4.00e-24	104.00
IUUC-Ont-071886	Oreochromis niloticus	37.43	1.00e-21	95.90
IUUC-Ocu-074282	Oryctolagus cuniculus	40.74	1.00e-23	102.00
IUUC-Oga-088403	Otolemur garnettii	44.38	7.00e-27	113.00
IUUC-Oar-089665	Ovis aries	55.10	3.00e-11	59.30
IUUC-Ptr-090580	Pan troglodytes	54.43	2.00e-21	95.50
IUUC-Pan-092447	Papio anubis	40.74	5.00e-23	100.00
IUUC-Psi-093673	Pelodiscus sinensis	41.15	4.00e-28	117.00
IUUC-Pfo-096933	Poecilia formosa	34.27	2.00e-18	85.50
IUUC-Pab-097867	Pongo abelii	54.43	3.00e-21	95.10
IUUC-Pva-102146	Pteropus vampyrus	55.70	2.00e-21	95.10
IUUC-Rno-105897	Rattus norvegicus	40.85	1.00e-22	99.40
IUUC-Sha-107282	Sarcophilus harrisii	37.86	1.00e-20	92.80
IUUC-Sar-113260	Sorex araneus	40.74	3.00e-23	101.00
IUUC-Ssc-115449	Sus scrofa	61.19	2.00e-19	88.60
IUUC-Tgu-117349	Taeniopygia guttata	44.59	1.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence